ABE1944MI
MilliporeSigma™ anti-Aprataxin, Polyclonal
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABE1944MI-Each-of-1 | In Stock | ₹ 38,734.72 |
ABE1944MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
Aprataxin
Classification
Polyclonal
Formulation
Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols
APTX, AOA, AOA1, AXA1, EAOH, EOAHA
Immunogen
Recombinant full-length human aprataxin.
Quantity
100 μL
Research Discipline
Epigenetics, Nuclear Function
Gene ID (Entrez)
NP_001182177
Target Species
Human
Form
Serum
Applications
Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Gene Accession No.
Q7Z2E3
Host Species
Rabbit
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Expected to react with all 13 human aprataxin spliced isoforms reported by UniProt (Q7Z2E3-1 through Q7Z2E3-13).
Content And Storage
−20°C for one year
Related Products
Description
- Specifically detects Aprataxin Clone: in Human samples, and it is validated for Immunoprecipitation, Western Blotting Aprataxin (UniProt Q7Z2E3; also known as FHA-HIT, Forkhead-associated domain histidine triad-like protein) is encoded by the APTX (also known as AOA, AOA1, AXA1, EAOH, EOAHA) gene (Gene ID 54840) in human
- Aprataxin contains an N-terminal forkhead-associated (FHA; a.a
- 38-87) domain akin to that found in the DNA end damage repair factor polynucleotide kinase phosphatase (PNKP), followed by a histidine triad (HIT; a.a
- 182-287) domain found in nucleoside hydrolases and transferases, and a C-terminal C2H2 type Zinc finger domain
- Aprataxin exhibits both DNA- and RNA-binding activity and plays a role in reversing toxic 5'-adenylated (5'-AMP) DNA lesions generated by DNA ligases when encountering nicked DNA structures with abnormal DNA termini
- Aprataxin functions as a DNA ligase proofreader to directly reverse damaged 5'-adenylated termini of DNA strand breaks that have been subjected to DNA damage-induced abortive processing by DNA ligases
- Ataxia with oculomotor apraxia type 1 (AOA1) is an autosomal recessive neurological syndrome caused by an impairment in DNA repair as a result of APTX gene mutations
- The related type 2 disorder AOA2 is caused by a Senataxin-deficiency due to SETX gene mutations.
Compare Similar Items
Show Difference
Antigen: Aprataxin
Classification: Polyclonal
Formulation: Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols: APTX, AOA, AOA1, AXA1, EAOH, EOAHA
Immunogen: Recombinant full-length human aprataxin.
Quantity: 100 μL
Research Discipline: Epigenetics, Nuclear Function
Gene ID (Entrez): NP_001182177
Target Species: Human
Form: Serum
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene Accession No.: Q7Z2E3
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with all 13 human aprataxin spliced isoforms reported by UniProt (Q7Z2E3-1 through Q7Z2E3-13).
Content And Storage: −20°C for one year
Antigen:
Aprataxin
Classification:
Polyclonal
Formulation:
Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols:
APTX, AOA, AOA1, AXA1, EAOH, EOAHA
Immunogen:
Recombinant full-length human aprataxin.
Quantity:
100 μL
Research Discipline:
Epigenetics, Nuclear Function
Gene ID (Entrez):
NP_001182177
Target Species:
Human
Form:
Serum
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
Q7Z2E3
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with all 13 human aprataxin spliced isoforms reported by UniProt (Q7Z2E3-1 through Q7Z2E3-13).
Content And Storage:
−20°C for one year
Antigen: __
Classification: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Applications: __
Conjugate: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Antigen:
__
Classification:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__
Applications:
__
Conjugate:
__
Gene Accession No.:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Antigen: PRDM9
Classification: Polyclonal
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: PRDM9;PFM6
Immunogen: GST-tagged recombinant fragment corresponding to 191 amino acids from the N-terminal half of human Histone-lysine N-methyltransferase PRDM9.
Quantity: 25 μg
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): __
Target Species: Mouse, Human
Form: Purified
Applications: Western Blot
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects Histone-lysine N-methyltransferase PRDM9 in human and mouse cells. It targets an epitope within 191 amino acids from the N-terminal half.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Antigen:
PRDM9
Classification:
Polyclonal
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
PRDM9;PFM6
Immunogen:
GST-tagged recombinant fragment corresponding to 191 amino acids from the N-terminal half of human Histone-lysine N-methyltransferase PRDM9.
Quantity:
25 μg
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
__
Target Species:
Mouse, Human
Form:
Purified
Applications:
Western Blot
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects Histone-lysine N-methyltransferase PRDM9 in human and mouse cells. It targets an epitope within 191 amino acids from the N-terminal half.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Antigen: RLIM/Rnf12
Classification: Polyclonal
Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols: Rlim; Rnf12
Immunogen: Recombinant protein corresponding to mouse RLIM/Rnf12.
Quantity: 100 μL
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_035406
Target Species: Hamster, Human, Mouse
Form: Serum
Applications: ChIP Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate: __
Gene Accession No.: Q9WTV7
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen:
RLIM/Rnf12
Classification:
Polyclonal
Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Symbols:
Rlim; Rnf12
Immunogen:
Recombinant protein corresponding to mouse RLIM/Rnf12.
Quantity:
100 μL
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_035406
Target Species:
Hamster, Human, Mouse
Form:
Serum
Applications:
ChIP Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate:
__
Gene Accession No.:
Q9WTV7
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.