ABN1383MI

MilliporeSigma™ Rabbit anti-phospho-TrkA (Tyr794), Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN1383MI-Each-of-1 In Stock ₹ 39,063.27

ABN1383MI - Each of 1

₹ 39,063.27

In Stock

Quantity

1

Base Price: ₹ 39,063.27

GST (18%): ₹ 7,031.389

Total Price: ₹ 46,094.659

Antigen

phospho-TrkA (Tyr794)

Classification

Polyclonal

Gene Accession No.

P35739

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Rat

Applications

Immunocytochemistry, Western Blot

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

Ntrk1; Trk; Trka

Immunogen

Linear peptide corresponding to rat TrkA sequence near the C-terminus with phosphorylated Tyr794.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_067600

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

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Description

  • Specifically detects phospho-TrkA (Tyr794) in Human, Rat samples, and it is validated for Immunocytochemistry, Western Blotting High affinity nerve growth factor receptor (EC 2.7.10.1; UniProt P35739; also known as Neurotrophic tyrosine kinase receptor type 1, p140-TrkA, Slow nerve growth factor receptor, Trk-A, TrkA neurotrophin receptor, TrkA proto-oncogene receptor, Tropomyosin-related kinase A) is encoded by the Ntrk1 gene (also known as Trk, Trka) in rat (Gene ID 59109)
  • Neurotrophins mediate a wide range of neuronal functions, including survival, differentiation, growth, and death, via two classes of transmembrane receptors, the Trk receptor tyrosine kinase and the p75 neurotrophin receptor
  • While nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and NT-4 all bind the p75 receptor, TrkA is selective for NGF, TrkB is selective for BDNF and NT-4, and TrkC is selective for NT-3
  • TrkA and TrkB receptors can also be activated by ligands of the G-protein-coupled receptor (GPCRs), including the nucleoside adenosine or adenosine agonists, such as CGS 21680 and the pituitary adenylate cyclase-activating polypeptide (PACAP)
  • In addition to transactivation via GPCRs, Glucocorticoids (GCs) are also reported to promote TrkA/B/C activation due to signaling cross-talk between Trk and GC receptor (GR).

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ABN1383MI

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Antigen:
phospho-TrkA (Tyr794)

Classification:
Polyclonal

Gene Accession No.:
P35739

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Rat

Applications:
Immunocytochemistry, Western Blot

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Ntrk1; Trk; Trka

Immunogen:
Linear peptide corresponding to rat TrkA sequence near the C-terminus with phosphorylated Tyr794.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_067600

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

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ABN1387MI

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Antigen:
Beta-glucocerebrosidase (GBA)

Classification:
Polyclonal

Gene Accession No.:
P04062

Host Species:
Mouse

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Applications:
Immunohistochemistry (Paraffin), Western Blot

Formulation:
Mouse polyclonal antibody serum with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
His-tagged recombinant full-length human mature Beta-glucocerebrosidase (GBA).

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_000148

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

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Antigen:
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Classification:
__

Gene Accession No.:
__

Host Species:
__

Purification Method:
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Regulatory Status:
__

Primary or Secondary:
__

Target Species:
__

Applications:
__

Formulation:
__

Gene Symbols:
__

Immunogen:
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Quantity:
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Research Discipline:
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Gene ID (Entrez):
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Content And Storage:
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Antigen:
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Classification:
Polyclonal

Gene Accession No.:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Formulation:
__

Gene Symbols:
MUL1,C1orf166,GIDE,MAPL,MULAN,RNF218

Immunogen:
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Quantity:
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Research Discipline:
Neuroscience

Gene ID (Entrez):
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Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.