ABN1455

MilliporeSigma™ NKX6.2, Rabbit, Unlabeled, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN1455-Each-of-1 In Stock ₹ 39,063.27

ABN1455 - Each of 1

₹ 39,063.27

In Stock

Quantity

1

Base Price: ₹ 39,063.27

GST (18%): ₹ 7,031.389

Total Price: ₹ 46,094.659

Antigen

NKX6.2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NKX6-2, GTX, NKX6B

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This rabbit polyclonal antibody detected the exogenously expressed human NKX6.2 in transfected HEK293T cells, while no immunoreactive bands were detected in lysates from untransfected cells. The immunogen sequence lies within the region C-terminal to the Homeobox and is 100% conserved among human, mouse, and rat species.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Applications

Western Blot

Concentration

Please refer to lot specific datasheet.

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

Q9C056

Immunogen

KLH-conjugated linear peptide corresponding to a C-terminal region sequence of human/mouse/rat NKX6.2.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_796374

Target Species

Human

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Description

  • Homeobox protein Nkx-6.2 (UniProt Q9C056; also known as Homeobox protein NK-6 homolog B) is encoded by the NKX6-2 (also known as GTX, NKX6B) gene (Gene ID 84504) in human
  • Mammalian NKX gene products and their orthologs in other species are known to regulators of neuronal cell fate
  • Both the ventral nervous system defective (vnd) gene product in Drosophila and murine NKX proteins in spinal cord direct progenitors to adopt specific ventral neural identities
  • In mice, NKX6.2 is expressed in a small subset of ventral neural progenitors in a restricted spatial pattern at the border between the medial and caudal ganglionic eminence (MGE and CGE)
  • NKX6,2 is required for specification of V1 interneurons in the spinal cord and progenitors are found to adopt a more dorsal V0 identity in the absence of NKX6,2
  • In addition, NKX6.2-positive brain region is shown to give rise to both parvalbumin (PV) and somatostatin (SST) cortical interneurons and in particular be enriched in a subpopulation of SST cortical interneurons that coexpress calretinin (CR).

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MilliporeSigma™

ABN1455

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Antigen:
NKX6.2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NKX6-2, GTX, NKX6B

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This rabbit polyclonal antibody detected the exogenously expressed human NKX6.2 in transfected HEK293T cells, while no immunoreactive bands were detected in lysates from untransfected cells. The immunogen sequence lies within the region C-terminal to the Homeobox and is 100% conserved among human, mouse, and rat species.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q9C056

Immunogen:
KLH-conjugated linear peptide corresponding to a C-terminal region sequence of human/mouse/rat NKX6.2.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_796374

Target Species:
Human

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Antigen:
GRP-78

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antibody detects GRP-78 protein in multiple mammalian species. It targets an epitope within 17 amino acids from the C-terminal region.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
KLH-conjugated linear peptide corresponding to 17 amino acids from the C-terminal region of human GRP-78.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_005338

Target Species:
Human

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Fischer Scientific

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Antigen:
TREM-2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antibody antibody detects Triggering receptor expressed on myeloid cells 2 in several regions of human brain. It targets an epitope within 13 amino acids from the C-terminal region.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
KLH-conjugated linear peptide corresponding to 13 amino acids from the C-terminal region of human TREM-2.

Quantity:
25 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
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Target Species:
Human

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Antigen:
TREM-2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antibody antibody detects Triggering receptor expressed on myeloid cells 2 in several regions of human brain. It targets an epitope within 13 amino acids from the C-terminal region.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
KLH-conjugated linear peptide corresponding to 13 amino acids from the C-terminal region of human TREM-2.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_061838

Target Species:
Human