ABS1008MI
MilliporeSigma™ phospho Glucocorticoid Receptor (Ser134), Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS1008MI-Each-of-1 | In Stock | ₹ 39,063.27 |
ABS1008MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,063.27
GST (18%): ₹ 7,031.389
Total Price: ₹ 46,094.659
Antigen
phospho Glucocorticoid Receptor (Ser134)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NR3C1, GCCR, GCR, GCRST, GRL
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
The target phosphorylation site recognized by this polyclonal antibody is present in all 9 human GR spliced isoforms (Ser108 of isoforms Alpha-B and Beta-B; Ser134 of all the other isoforms) and in both rat GR spliced isoforms (Ser155 of isoform A and Ser128 of isoform B) reported by UniProt (P04150 and P06536, respectively).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in Tris-buffered saline (pH 8.0) with 0.05% Sodium Azide.
Gene Accession No.
P04150
Immunogen
Linear peptide corresponding to a human glucocorticoid receptor sequence containing phosphorylated Ser134.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_000167
Target Species
Human
Related Products
Description
- Glucocorticoid receptor (UniProt P04150; also known as GR, Nuclear receptor subfamily 3 group C member 1) is encoded by the NR3C1 (also known as GCCR, GCR, GCRST, GRL) gene (Gene ID 2908) in human
- Glucocorticoid receptor is widely expressed in almost all cell types and regulates genes that control development, metabolism, and immune response upon binding glucocorticoids
- Hormone-bound GR translocates from the cytoplasm to the nucleus where it regulates gene transcriptions by binding to glucocorticoid response elements (GREs) or by interacting with various transcription factors
- Alternatively, hormone-bound GR can represses gene transcriptions by blocking the nuclear translocation of transcription factors
- BDNF-stimulated TrkB activation is shown to induce GR phosphorylation at Ser155 and Ser287 in primary rat cortical neurons (equivalent to human GR Ser134 and Ser267), resulting in enhanced GR transcription activity
- GR is composed of an N-terminal modulating domain (a.a
- 1-420), a DNA-binding domain (a.a
- 421-486), and a C-terminal ligand-binding domain (a.a
- 528-777).
Compare Similar Items
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Antigen: phospho Glucocorticoid Receptor (Ser134)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NR3C1, GCCR, GCR, GCRST, GRL
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The target phosphorylation site recognized by this polyclonal antibody is present in all 9 human GR spliced isoforms (Ser108 of isoforms Alpha-B and Beta-B; Ser134 of all the other isoforms) and in both rat GR spliced isoforms (Ser155 of isoform A and Ser128 of isoform B) reported by UniProt (P04150 and P06536, respectively).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in Tris-buffered saline (pH 8.0) with 0.05% Sodium Azide.
Gene Accession No.: P04150
Immunogen: Linear peptide corresponding to a human glucocorticoid receptor sequence containing phosphorylated Ser134.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_000167
Target Species: Human
Antigen:
phospho Glucocorticoid Receptor (Ser134)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NR3C1, GCCR, GCR, GCRST, GRL
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
The target phosphorylation site recognized by this polyclonal antibody is present in all 9 human GR spliced isoforms (Ser108 of isoforms Alpha-B and Beta-B; Ser134 of all the other isoforms) and in both rat GR spliced isoforms (Ser155 of isoform A and Ser128 of isoform B) reported by UniProt (P04150 and P06536, respectively).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in Tris-buffered saline (pH 8.0) with 0.05% Sodium Azide.
Gene Accession No.:
P04150
Immunogen:
Linear peptide corresponding to a human glucocorticoid receptor sequence containing phosphorylated Ser134.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000167
Target Species:
Human
Antigen: HSD17B7
Classification: Polyclonal
Conjugate: __
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: __
Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
Gene Accession No.: Q62904
Immunogen: Purified protein corresponding to rat HSD17B7.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_058931
Target Species: Bovine, Hamster, Human, Mouse, Rat
Antigen:
HSD17B7
Classification:
Polyclonal
Conjugate:
__
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
__
Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Accession No.:
Q62904
Immunogen:
Purified protein corresponding to rat HSD17B7.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_058931
Target Species:
Bovine, Hamster, Human, Mouse, Rat
Antigen: MTHFR
Classification: Polyclonal
Conjugate: __
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications: Western Blot
Concentration: __
Formulation: Rabbit polyclonal serum with 0.05% sodium azide.
Gene Accession No.: P42898
Immunogen: Recombinant protein corresponding to human MTHFR.
Quantity: 200 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_005948
Target Species: Human, Mouse, Porcine
Antigen:
MTHFR
Classification:
Polyclonal
Conjugate:
__
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Applications:
Western Blot
Concentration:
__
Formulation:
Rabbit polyclonal serum with 0.05% sodium azide.
Gene Accession No.:
P42898
Immunogen:
Recombinant protein corresponding to human MTHFR.
Quantity:
200 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_005948
Target Species:
Human, Mouse, Porcine
Antigen: PHLPP2
Classification: Polyclonal
Conjugate: __
Gene: __
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Applications: Immunocytochemistry, Western Blot
Concentration: __
Formulation: Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: Q6ZVD8
Immunogen: KLH-conjugated linear peptide corresponding within the PP2C-like domain of human PHLPP2.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_055835
Target Species: Human
Antigen:
PHLPP2
Classification:
Polyclonal
Conjugate:
__
Gene:
__
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Applications:
Immunocytochemistry, Western Blot
Concentration:
__
Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
Q6ZVD8
Immunogen:
KLH-conjugated linear peptide corresponding within the PP2C-like domain of human PHLPP2.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_055835
Target Species:
Human