ABN897

MilliporeSigma™ AXL (UFO), Rabbit, Unlabeled, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN897-Each-of-1 In Stock ₹ 43,707.47

ABN897 - Each of 1

₹ 43,707.47

In Stock

Quantity

1

Base Price: ₹ 43,707.47

GST (18%): ₹ 7,867.345

Total Price: ₹ 51,574.815

Antigen

AXL (UFO)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AXL, UFO

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This rabbit polyclonal antibody targets cytoplasmic C-terminal end region present in both spliced isoforms of human AXL (UFO) reported by UniProt (P30530). This antibody will not detect internalized portion, but not the extracellular portion of the receptor following its cleavage by ADAM10.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Applications

Western Blot

Concentration

Please refer to lot specific datasheet.

Formulation

Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

P30530

Immunogen

GST-tagged human AXL (UFO) C-terminal end fragment lacking most of the kinase domain sequence.

Quantity

100 μL

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_068713

Target Species

Human

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Description

  • Sterol regulatory element-binding protein cleavage-activating protein (UniProt P97260; also known as SCAP, SREBP cleavage-activating protein) is encoded by the SCAP gene (Gene ID 100689048) in hamster species
  • SCAP mediates the activation of membrane-bound transcription factors SREBPs (sterol-regulatory element binding proteins) for transcribing genes encoding cholesterol biosynthetic enzymes
  • In sterol-deprived cells, SCAP escorts SREBPs from ER to Golgi, where active fragments of SREBPs are released from membrane by proteolysis
  • Sterol accumulation inuduces a negative regulatory mechanism, where SCAP becomes bound by Insigs and trapped in the ER, preventing further delivery of SREBPs to the Golgi for proteolytic release
  • SCAP spans the ER membrane eight times (a.a
  • 19-39, 280-300, 313-333, 345-365, 402-422, 424-444, 519-539, 709-729) with

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MilliporeSigma™

ABN897

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Antigen:
AXL (UFO)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AXL, UFO

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This rabbit polyclonal antibody targets cytoplasmic C-terminal end region present in both spliced isoforms of human AXL (UFO) reported by UniProt (P30530). This antibody will not detect internalized portion, but not the extracellular portion of the receptor following its cleavage by ADAM10.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P30530

Immunogen:
GST-tagged human AXL (UFO) C-terminal end fragment lacking most of the kinase domain sequence.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_068713

Target Species:
Human

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ABN898MI

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Antigen:
BMP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BMP2, BMP2A

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This rabbit polyclonal antibody targets a region present in Prepro-, pro-, and mature human BMP2.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P12643

Immunogen:
GST-tagged recombinant protein composed of the propeptide C-terminal region and the mature human BMP2 N-terminal region.

Quantity:
200 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_001191

Target Species:
Human

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Antigen:
__

Classification:
__

Conjugate:
__

Gene:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Test Specificity:
__

Content And Storage:
__

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
__

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Antigen:
Huntingtin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This rabbit polyclonal antibody detects Huntington disease protein in human and mouse brain. It targets an epitope within 180 amino acids from the N-terminal region.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
__

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Accession No.:
__

Immunogen:
GST/His-tagged recombinant fragment corresponding to 180 amino acids from the N-terminal region of human Huntington disease protein .

Quantity:
25 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
__

Target Species:
Mouse, Human