BDB558217
Histone H3 (pS28) Rat, Alexa Fluor 647, Clone: HTA28, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB558217-Each-of-1 | In Stock | ₹ 26,309.70 |
BDB558217 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 26,309.70
GST (18%): ₹ 4,735.746
Total Price: ₹ 31,045.446
Antigen
Histone H3 (pS28)
Classification
Monoclonal
Conjugate
Alexa Fluor 647
Host Species
Rat
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications
Flow Cytometry
Clone
HTA28
Formulation
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen
Phosphorylated Human Histone H3 Peptide
Quantity
50 Tests
Research Discipline
Cell Biology
Target Species
Bovine, Fly, Hamster, Human, Mouse, Rat
Isotype
IgG2a κ
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Description
- Histones are highly basic proteins that complex with DNA to form chromatin
- Histone H3 is a ∽15kDa protein that is phosphorylated at serine 28 (S28), S10, and/or threonine 11 during mammalian cell mitosis and meiosis
- The phosphorylation sites are located in the N-terminal tail, a region that is outside of the chromatin fiber and is thus accessible for interactions with agents that may regulate chromatin or specific gene activities
- The phosphorylation states of the two serine sites during the cell cycle are highly regulated by Aurora B kinase and a PP1 phosphatase: S10 is in the phosphorylated state from late G2 phase to anaphase, while S28 is phosphorylated from prophase to anaphase
- Furthermore, phosphorylation of histone H3 S28 may be mediated by other kinases in response to external stimuli
- Evidence suggests that histone phosphorylation is involved in the regulation of chromosome condensation, cell division, and gene transcription
- The HTA28 monoclonal antibody reacts with histone H3 phosphorylated at S28 in its N-terminal tail
- It does not recognize the unphosphorylated protein
- Host Species: Rat Clone: HTA28 Isotype: IgG2a, κ Cross Reactivity: Human, Mouse Flow Cytometry, Intracellular Staining
Compare Similar Items
Show Difference
Antigen: Histone H3 (pS28)
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: HTA28
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Human Histone H3 Peptide
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Bovine, Fly, Hamster, Human, Mouse, Rat
Isotype: IgG2a κ
Antigen:
Histone H3 (pS28)
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
HTA28
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Human Histone H3 Peptide
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Bovine, Fly, Hamster, Human, Mouse, Rat
Isotype:
IgG2a κ
Antigen: DCIR
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: I3-612
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: __
Quantity: 100 Tests
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1 κ
Antigen:
DCIR
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
I3-612
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
__
Quantity:
100 Tests
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Stat6 (pY641)
Classification: Monoclonal
Conjugate: Alexa Fluor 647
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications: Flow Cytometry
Clone: J71-773.58.11
Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen: Phosphorylated Mouse STAT6 (Y641) Peptide
Quantity: 50 Tests
Research Discipline: Cell Biology
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
Stat6 (pY641)
Classification:
Monoclonal
Conjugate:
Alexa Fluor 647
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Applications:
Flow Cytometry
Clone:
J71-773.58.11
Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Immunogen:
Phosphorylated Mouse STAT6 (Y641) Peptide
Quantity:
50 Tests
Research Discipline:
Cell Biology
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: α-Synuclein (pY125)
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C
Applications: Western Blot
Clone: I57-628
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen: Phosphorylated peptide corresponding to the region including the Tyrosine 125 residue of α-Synuclein
Quantity: 0.1 mg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG2b κ
Antigen:
α-Synuclein (pY125)
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C
Applications:
Western Blot
Clone:
I57-628
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Immunogen:
Phosphorylated peptide corresponding to the region including the Tyrosine 125 residue of α-Synuclein
Quantity:
0.1 mg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG2b κ