BDB558217

Histone H3 (pS28) Rat, Alexa Fluor 647, Clone: HTA28, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB558217-Each-of-1 In Stock ₹ 27,367.50

BDB558217 - Each of 1

₹ 27,367.50

In Stock

Quantity

1

Base Price: ₹ 27,367.50

GST (18%): ₹ 4,926.15

Total Price: ₹ 32,293.65

Antigen

Histone H3 (pS28)

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Host Species

Rat

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

HTA28

Formulation

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen

Phosphorylated Human Histone H3 Peptide

Quantity

50 Tests

Research Discipline

Cell Biology

Target Species

Bovine, Fly, Hamster, Human, Mouse, Rat

Isotype

IgG2a κ

Related Products

Img

BD Biosciences

BDB558428

--

Img

BD Biosciences

BDB558630

--

Img

BD Biosciences

BDB558438

--

Img

BD Biosciences

BDB558507

--

Img

BD Biosciences

BDB558435

--

Img

BD Biosciences

BDB558560

--

Img

BD Biosciences

BDB558557

--

Img

BD Biosciences

BDB558129

--

Description

  • Histones are highly basic proteins that complex with DNA to form chromatin
  • Histone H3 is a ∽15kDa protein that is phosphorylated at serine 28 (S28), S10, and/or threonine 11 during mammalian cell mitosis and meiosis
  • The phosphorylation sites are located in the N-terminal tail, a region that is outside of the chromatin fiber and is thus accessible for interactions with agents that may regulate chromatin or specific gene activities
  • The phosphorylation states of the two serine sites during the cell cycle are highly regulated by Aurora B kinase and a PP1 phosphatase: S10 is in the phosphorylated state from late G2 phase to anaphase, while S28 is phosphorylated from prophase to anaphase
  • Furthermore, phosphorylation of histone H3 S28 may be mediated by other kinases in response to external stimuli
  • Evidence suggests that histone phosphorylation is involved in the regulation of chromosome condensation, cell division, and gene transcription
  • The HTA28 monoclonal antibody reacts with histone H3 phosphorylated at S28 in its N-terminal tail
  • It does not recognize the unphosphorylated protein
  • Host Species: Rat Clone: HTA28 Isotype: IgG2a, κ Cross Reactivity: Human, Mouse Flow Cytometry, Intracellular Staining

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB558217

--


Antigen:
Histone H3 (pS28)

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Host Species:
Rat

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
HTA28

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated Human Histone H3 Peptide

Quantity:
50 Tests

Research Discipline:
Cell Biology

Target Species:
Bovine, Fly, Hamster, Human, Mouse, Rat

Isotype:
IgG2a κ

Img

BD Biosciences

BDB558220

--


Antigen:
DCIR

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
I3-612

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
__

Quantity:
100 Tests

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB558242

--


Antigen:
Stat6 (pY641)

Classification:
Monoclonal

Conjugate:
Alexa Fluor 647

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
J71-773.58.11

Formulation:
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Immunogen:
Phosphorylated Mouse STAT6 (Y641) Peptide

Quantity:
50 Tests

Research Discipline:
Cell Biology

Target Species:
Mouse

Isotype:
IgG1 κ

Img

BD Biosciences

BDB558246

--


Antigen:
α-Synuclein (pY125)

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C

Applications:
Western Blot

Clone:
I57-628

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Immunogen:
Phosphorylated peptide corresponding to the region including the Tyrosine 125 residue of α-Synuclein

Quantity:
0.1 mg

Research Discipline:
Cell Biology

Target Species:
Human

Isotype:
IgG2b κ