BDB610697

DHFR Mouse, Unlabeled, Clone: 49, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB610697-Each-of-1 In Stock ₹ 45,004.56

BDB610697 - Each of 1

₹ 45,004.56

In Stock

Quantity

1

Base Price: ₹ 45,004.56

GST (18%): ₹ 8,100.821

Total Price: ₹ 53,105.381

Antigen

DHFR

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Quantity

150 μg

Research Discipline

Cell Biology

Target Species

Canine, Human, Mouse, Rat

Isotype

IgG1

Applications

Western Blot

Clone

49

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Dihydrofolate reductase (DHFR) regenerates tetrahydrofolate from dihydrofolate in the presence of NADPH
  • Tetrahydrofolate is the coenzyme for thymidilate synthetase in the biosynthesis of thymidine and is also critical for the synthesis of amino acids and purines
  • DHFR is a protein of 186 amino acids that is highly conserved among different organisms
  • DHFR levels change during the cell cycle, with the highest content during the G1/S transition
  • Expression of DHFR tightly correlates with the turnover rate of its mRNA
  • Because dividing cells require a continuous supply of thymidine, DHFR has been a target for anticancer drugs
  • The folic acid antagonists aminopterin and amethopterin (methotrexate), widely used in cancer treatments, inhibit DHFR
  • However, over long treatments, treated cells often amplify the DHFR gene, producing drug-resistant cells.

Compare Similar Items

Show Difference

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BD Biosciences

BDB610697

--


Antigen:
DHFR

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
49

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

BDB610700

--


Antigen:
BM28

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
46

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

BDB610701

--


Antigen:
BM28

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
46

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

BD Biosciences

BDB610702

--


Antigen:
NFAT-1

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Human

Isotype:
IgG1

Applications:
Western Blot

Clone:
1

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.