BDB611415
gp91[phox] Mouse, Unlabeled, Clone: 53, BD
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB611415-Each-of-1 | In Stock | ₹ 50,908.00 |
BDB611415 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,908.00
GST (18%): ₹ 9,163.44
Total Price: ₹ 60,071.44
Antigen
gp91[phox]
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Mouse gp91[phox] aa. 450-556
Quantity
150 μg
Research Discipline
Cell Biology
Target Species
Mouse, Rat
Isotype
IgG1
Applications
Western Blot
Clone
53
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
Related Products
Description
- Although dormant in resting granulocytes, macrophages, and B lymphocytes, the neutrophil respiratory burst oxidase (NADPH-oxidase) generates superoxide and secondary oxygen-derived toxic products in response to bacteria or a variety of soluble stimuli
- It is an integral membrane cytochrome, b558, which consists of two subunits, gp91[phox] and p21[phox]
- Upon stimulation, cytochrome b558 forms a complex with cytosolic proteins, p67[phox], p47[phox], p40[phox], and rac2 and produces superoxide anions in a NADPH-dependent manner
- In chronic granulomatous disease (CGD), severe recurrent bacterial and fungal infections result from defective NADPH-oxidase activity
- The majority of CGD cases are caused by a defective gp91[phox] gene
- gp91[phox], implicated as a docking site for p47[phox], is membrane glycoprotein with multiple N-terminal hydrophobic domains and a hydrophilic C-terminus
- The expression of gp91[phox] is restricted to terminally differentiated phagocytes and B lymphocytes
- This cell type- and developmental stage-specific expression may be controlled by transcriptional activators, such as PU.1 and YY1, and transcriptional repressors, such as CCAAT displacement protein (CDP)
- Endogenous mouse gp91phox shows 58kDa band, instead of 91kDa observed in human
- Both mouse and human deglycosylated gp91 are 54kDa
- This difference may be due to less glycosylation sites in the mouse sequence
- Host Species: Mouse Clone: 53 Isotype: IgG1 Species Reactivity: Mouse Immunogen: Mouse gp91[phox] aa
- 450-556 Formula Weight [Chemical]: 58kDa Immunofluorescence, Western Blotting
Compare Similar Items
Show Difference
Antigen: gp91[phox]
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Mouse gp91[phox] aa. 450-556
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 53
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
gp91[phox]
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Mouse gp91[phox] aa. 450-556
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
53
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: UBE3A
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Mouse UBE3A aa. 501-712
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG1
Applications: Western Blot
Clone: 13
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
UBE3A
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Mouse UBE3A aa. 501-712
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG1
Applications:
Western Blot
Clone:
13
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: __
Classification: __
Concentration: __
Formulation: __
Immunogen: __
Quantity: 1 Kit
Research Discipline: __
Target Species: __
Isotype: __
Applications: __
Clone: __
Conjugate: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Content And Storage: __
Antigen:
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Classification:
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Concentration:
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Formulation:
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Immunogen:
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Quantity:
1 Kit
Research Discipline:
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Target Species:
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Isotype:
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Applications:
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Clone:
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Conjugate:
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Host Species:
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Purification Method:
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Regulatory Status:
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Primary or Secondary:
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Content And Storage:
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Antigen: __
Classification: __
Concentration: 1 mg/mL
Formulation: __
Immunogen: __
Quantity: 500 μg
Research Discipline: __
Target Species: __
Isotype: __
Applications: __
Clone: __
Conjugate: __
Host Species: Human
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Content And Storage: -20°C
Antigen:
__
Classification:
__
Concentration:
1 mg/mL
Formulation:
__
Immunogen:
__
Quantity:
500 μg
Research Discipline:
__
Target Species:
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Isotype:
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Applications:
__
Clone:
__
Conjugate:
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Host Species:
Human
Purification Method:
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Regulatory Status:
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Primary or Secondary:
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Content And Storage:
-20°C