BDB742997
Siglec-1 (CD169) Mouse anti-Human, BUV395, Clone: 7-239, BD Optibuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB742997-Each-of-1 | In Stock | ₹ 47,400.24 |
BDB742997 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,400.24
GST (18%): ₹ 8,532.043
Total Price: ₹ 55,932.283
Antigen
Siglec-1 (CD169)
Clone
7-239
Conjugate
Brilliant Ultraviolet 395
Gene Alias
Sialoadhesin, SN, SIGLEC1, Siglec-1, Sialic acid-binding Ig-like lectin 1
Immunogen
Human Rhinovirus-infected Dendritic Cells
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The 7-239 monoclonal antibody specifically binds to Sialic acid-binding Ig-like lectin 1 (Siglec-1), which is also known as Sialoadhesin (SN), or CD169
- Siglec-1 is a type I transmembrane glycoprotein that belongs to the Siglec family within the Ig superfamily
- This adhesion molecule especiallybinds to glycolipids and glycoproteins with terminal α-2 sialyl residues.Siglec-1 is expressed by macrophages and dendritic cells and serves as a cellular interaction molecule
- Its expression can be upregulated by cells in response to type II collagen, or to cytokines including interferons, and tumor necrosis factor
- Siglec-1 plays roles in endocytosis, hematopoiesis, and leucocyte migration
- It mediates macrophage binding to various cell types including developing and mature leucocytes
- Siglec-1 that is expressed by dendritic cells can also bind HIV-1 and may mediate viral transfer to bystander CD4+ T cells
- Several Siglec-1 counter-receptors have been described including CD43, CD206, and CD227 which are expressed by T cells, macrophages, or breast cancer cells, respectively
- The 7-239 antibody reportedly blocks Siglec-1 functions in some cellular assay systems
- The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes
- This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry
- With an Ex Max at 348 nm and an Em Max at 395 nm, BD Horizon BUV395 can be excited with a 355 nm laser and detected with a 379/28 filter
- BUV395 is a UV-excitable dye that has been developed exclusively by BD Biosciences
- With an excitation max of 348 nm and emission max of 395 nm, BUV395 can be excited by the 355nm laser and detected in a 379/28 filter
- This dye is optimal for multicolor flow cytometry because it has little to no spillover into other detectors.
Compare Similar Items
Show Difference
Antigen: Siglec-1 (CD169)
Clone: 7-239
Conjugate: Brilliant Ultraviolet 395
Gene Alias: Sialoadhesin, SN, SIGLEC1, Siglec-1, Sialic acid-binding Ig-like lectin 1
Immunogen: Human Rhinovirus-infected Dendritic Cells
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
Siglec-1 (CD169)
Clone:
7-239
Conjugate:
Brilliant Ultraviolet 395
Gene Alias:
Sialoadhesin, SN, SIGLEC1, Siglec-1, Sialic acid-binding Ig-like lectin 1
Immunogen:
Human Rhinovirus-infected Dendritic Cells
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Vβ 5.1, 5.2 T-Cell Receptor
Clone: MR9-4
Conjugate: Brilliant Violet 421
Gene Alias: TCR Vβ5.1/5.2, Vβ5 T-cell receptor, T cell receptor beta 5
Immunogen: Mouse T-Cell Hybridoma 2HB51.8
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
Vβ 5.1, 5.2 T-Cell Receptor
Clone:
MR9-4
Conjugate:
Brilliant Violet 421
Gene Alias:
TCR Vβ5.1/5.2, Vβ5 T-cell receptor, T cell receptor beta 5
Immunogen:
Mouse T-Cell Hybridoma 2HB51.8
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: Vβ 5.1, 5.2 T-Cell Receptor
Clone: MR9-4
Conjugate: Brilliant Violet 510
Gene Alias: TCR Vβ5.1/5.2, Vβ5 T-cell receptor, T cell receptor beta 5
Immunogen: Mouse T-Cell Hybridoma 2HB51.8
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
Vβ 5.1, 5.2 T-Cell Receptor
Clone:
MR9-4
Conjugate:
Brilliant Violet 510
Gene Alias:
TCR Vβ5.1/5.2, Vβ5 T-cell receptor, T cell receptor beta 5
Immunogen:
Mouse T-Cell Hybridoma 2HB51.8
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ
Antigen: Vβ 5.1, 5.2 T-Cell Receptor
Clone: MR9-4
Conjugate: Brilliant Violet 605
Gene Alias: TCR Vβ5.1/5.2, Vβ5 T-cell receptor, T cell receptor beta 5
Immunogen: Mouse T-Cell Hybridoma 2HB51.8
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Mouse
Isotype: IgG1 κ
Antigen:
Vβ 5.1, 5.2 T-Cell Receptor
Clone:
MR9-4
Conjugate:
Brilliant Violet 605
Gene Alias:
TCR Vβ5.1/5.2, Vβ5 T-cell receptor, T cell receptor beta 5
Immunogen:
Mouse T-Cell Hybridoma 2HB51.8
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Mouse
Isotype:
IgG1 κ