FEMA550103

CD3z Recombinant Rabbit Monoclonal Antibody (21H6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550103-Each-of-1 In Stock ₹ 35,764.08

FEMA550103 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

CD3z

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P20963

Gene Symbols

CD247

Immunogen

A synthesized peptide derived from Human CD247

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry

Clone

21H6

Conjugate

Unconjugated

Gene

CD247

Gene Alias

4930549J05Rik, A430104F18Rik, antigen CD3Z, zeta polypeptide, AW552088, Cd247, CD247 antigen, CD247 antigen, zeta subunit, Cd247 molecule, Cd3, CD3 antigen, zeta polypeptide, CD3 zeta, CD3 zeta chain, CD3e antigen, CD3-epsilon, Cd3-eta, CD3H, CD3Q, Cd3z, CD3Z antigen, zeta polypeptide (TiT3 complex), Cd3zeta, Cd3-zeta, CD3zeta chain, CD3-zeta/eta, FLJ18683, IMD25, T3E, T3z, T-cell antigen receptor complex, zeta subunit of CD3, T-cell receptor CD3 subunit zeta, T-cell receptor CD3, subunit zeta, T-cell receptor T3 eta chain, T-cell receptor T3 zeta chain, T-cell receptor zeta chain, T-cell surface glycoprotein CD3 zeta chain, TCR zeta chain, TCRE, Tcrk, TCRZ, TCRzeta

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

919

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • CD3z complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex
  • T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta
  • These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11
  • The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules, and this association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits
  • CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation
  • The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum
  • It is never expressed on B or NK cells
  • Decreased percentages of T lymphocytes may be observed in some autoimmune diseases
  • Diseases associated with CD3z include Immunodeficiency 25 and T-B+ Severe Combined Immunodeficiency Due To Cd3delta/Cd3epsilon/Cd3zeta.

Compare Similar Items

Show Difference

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Thermo Scientific

FEMA550103

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Antigen:
CD3z

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P20963

Gene Symbols:
CD247

Immunogen:
A synthesized peptide derived from Human CD247

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry

Clone:
21H6

Conjugate:
Unconjugated

Gene:
CD247

Gene Alias:
4930549J05Rik, A430104F18Rik, antigen CD3Z, zeta polypeptide, AW552088, Cd247, CD247 antigen, CD247 antigen, zeta subunit, Cd247 molecule, Cd3, CD3 antigen, zeta polypeptide, CD3 zeta, CD3 zeta chain, CD3e antigen, CD3-epsilon, Cd3-eta, CD3H, CD3Q, Cd3z, CD3Z antigen, zeta polypeptide (TiT3 complex), Cd3zeta, Cd3-zeta, CD3zeta chain, CD3-zeta/eta, FLJ18683, IMD25, T3E, T3z, T-cell antigen receptor complex, zeta subunit of CD3, T-cell receptor CD3 subunit zeta, T-cell receptor CD3, subunit zeta, T-cell receptor T3 eta chain, T-cell receptor T3 zeta chain, T-cell receptor zeta chain, T-cell surface glycoprotein CD3 zeta chain, TCR zeta chain, TCRE, Tcrk, TCRZ, TCRzeta

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
919

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

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FEMA550104

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Antigen:
Phospho-Tau (Ser199)

Classification:
Recombinant Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P10636

Gene Symbols:
MAPT

Immunogen:
A synthesized peptide derived from Human MAPT

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)

Clone:
23E8

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4137

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

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FEMA550105

--


Antigen:
Phospho-Tau (Ser404)

Classification:
Recombinant Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P10636

Gene Symbols:
MAPT

Immunogen:
A synthesized peptide derived from Human MAPT

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
11H10

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4137

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

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FEMA550109

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Antigen:
tPA

Classification:
Recombinant Monoclonal

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P00750

Gene Symbols:
PLAT

Immunogen:
A synthesized peptide derived from Human PLAT

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry

Clone:
32B1

Conjugate:
Unconjugated

Gene:
PLAT

Gene Alias:
3.4.21.68, Alteplase, AU020998, AW212668, D8Ertd2e, PATISS, plasminogen activator, tissue, plasminogen activator, tissue type, plasminogen/activator kringle, PLAT, Reteplase, serine protease, t plasminogen activator, tissue plasminogen activator, tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, TPA, t-PA, t-plasminogen activator

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5327

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG