MABC983MI
MilliporeSigma™ Mouse anti-CD1d, Clone: D5,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABC983MI-Each-of-1 | In Stock | ₹ 41,307.51 |
MABC983MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,307.51
GST (18%): ₹ 7,435.352
Total Price: ₹ 48,742.862
Antigen
CD1d
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
CD1D
Immunogen
Pooled CD1d-GST fusion proteins containing α1 domain alone, α1-α2 domains, or α1–α3 domains.
Quantity
200 μg
Research Discipline
Apoptosis, Cancer
Gene ID (Entrez)
NP_001757
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2b κ
Applications
Immunoprecipitation, Western Blot
Clone
D5
Gene Accession No.
P15813
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects CD1d clone: D5 in Human samples, and it is validated for Immunoprecipitation, Western Blotting Antigen-presenting glycoprotein CD1d (UniProt P15813; also known as CD1d, R3G1) is encoded by the CD1D gene (Gene ID 912) in human
- CD1d is an MHC-like glycoprotein expressed on epithelial cells and can signal innate immune responses by presenting lipid antigen to natural killer (NK) and NK T (NKT) cells
- Similar to MHC class I heavy chain (HC), CD1d HC is glycosylated and assembled with β2m in ER
- Unlike MHC class I HC, misfoled CD1d and CD1d not properly assembled with β2m are not destroyed by ER quality control mechanisms
- CD1d plays a role in both innate and adaptive immunity to various bacteria, viruses, fungi, and parasites
- Activation of CD1d-restricted invariant NKT cells enhances host resistance to these microbes via direct killing of CD1d-expressing (infected) cells or by promoting interferon gamma release from conventional NK cells and by modulating adaptive immune cells via alteration of Th1/Th2 polarization
- Chlamydia trachomatis is shown to prevent CD1d-mediated innate immune destruction of the infected urethral epithelial cells by targeting CD1d for proteolytic degradation
- Specifically, the chlamydial proteasome-like activity factor (CPAF) interacts with the CD1d HC, and CPAF-associated CD1d HC is then ubiquitinated for eventual degradation.
Compare Similar Items
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Antigen: CD1d
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CD1D
Immunogen: Pooled CD1d-GST fusion proteins containing α1 domain alone, α1-α2 domains, or α1–α3 domains.
Quantity: 200 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_001757
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2b κ
Applications: Immunoprecipitation, Western Blot
Clone: D5
Gene Accession No.: P15813
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
CD1d
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CD1D
Immunogen:
Pooled CD1d-GST fusion proteins containing α1 domain alone, α1-α2 domains, or α1–α3 domains.
Quantity:
200 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_001757
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Immunoprecipitation, Western Blot
Clone:
D5
Gene Accession No.:
P15813
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: TRAF4
Classification: Monoclonal
Formulation: Mouse monoclonal IgG1 ascites without preservatives.
Gene Symbols: TRAF4, CART1, MLN62, RNF83
Immunogen: Linear peptide corresponding to Human TRAF4.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: −20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 5MLN-2H1
Gene Accession No.: NP_004286
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Ascites
Antigen:
TRAF4
Classification:
Monoclonal
Formulation:
Mouse monoclonal IgG1 ascites without preservatives.
Gene Symbols:
TRAF4, CART1, MLN62, RNF83
Immunogen:
Linear peptide corresponding to Human TRAF4.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
5MLN-2H1
Gene Accession No.:
NP_004286
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Ascites
Antigen: Semaphorin 4D/CD100
Classification: Monoclonal
Formulation: Purified rat monoclonal IgG2a in buffer containing PBS without preservatives.
Gene Symbols: Sema4d; Semacl2; Semaj
Immunogen: Recombinant protein corresponding to mouse Semaphorin 4D/CD100.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_001268809
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG2a
Applications: Functional Assay, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: BMA-12
Gene Accession No.: O09126
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Purified
Antigen:
Semaphorin 4D/CD100
Classification:
Monoclonal
Formulation:
Purified rat monoclonal IgG2a in buffer containing PBS without preservatives.
Gene Symbols:
Sema4d; Semacl2; Semaj
Immunogen:
Recombinant protein corresponding to mouse Semaphorin 4D/CD100.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_001268809
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG2a
Applications:
Functional Assay, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
BMA-12
Gene Accession No.:
O09126
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Purified
Antigen: TRADD
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: TRADD
Immunogen: GST-tagged recombinant protein corresponding to human TRADD.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_003780
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 1G6.1
Gene Accession No.: Q15628
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Rat
Form: Purified
Antigen:
TRADD
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
TRADD
Immunogen:
GST-tagged recombinant protein corresponding to human TRADD.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_003780
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
1G6.1
Gene Accession No.:
Q15628
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Rat
Form:
Purified