MABE1006MI

MilliporeSigma™ Mouse anti-N6-methyladenosine (m6A), Clone: 17-3-4-1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABE1006MI-Each-of-1 In Stock ₹ 41,999.69

MABE1006MI - Each of 1

₹ 41,999.69

In Stock

Quantity

1

Base Price: ₹ 41,999.69

GST (18%): ₹ 7,559.944

Total Price: ₹ 49,559.634

Antigen

N6-methyladenosine (m6A)

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG1λ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Immunogen

Hapten N6-methyladenosine-5'-mono-phosphate conjugated to BSA of all N6-methyladenosine (m6A).

Quantity

100 μg

Research Discipline

Epigenetics and Nuclear Function

Target Species

All species

Form

Purified

Applications

Dot Blot, Immunoprecipitation

Clone

17-3-4-1

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG1 λ

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Description

  • Specifically detects N6-methyladenosine (m6A) clone: 17-3-4-1 in All samples, and it is validated for Dot Blot, Immunoprecipitation N6-Methyladenosine (m6A ) is an abundant modification found in mRNA, tRNA, snRNA, as well as long non-coding RNA, in all species
  • RNA adenosine methylation is catalyzed by a multicomponent complex composed of METTL3/MT-A70, METTL14, and WTAP in mammals
  • METTL3 & METTL14 are responsible for the methyltransferase activity of the complex, and WTAP mediates substrate recruitment
  • Fat mass and obesity-associated (FTO) and ALKBH5 are two identified demethylases that catalyze oxidative demthylation of m6A
  • Several functions of m6A modification have been proposed, including mRNA decay, splicing regulation, RNA nuclear export and maturation
  • (PMID 25171402)
  • Anti-N6-methyladenosine (m6A), clone 17-3-4-1, is a mouse monoclonal that specifically detects RNA molecules with m6A modication.

Compare Similar Items

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Img

MilliporeSigma™

MABE1006MI

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Antigen:
N6-methyladenosine (m6A)

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1λ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Immunogen:
Hapten N6-methyladenosine-5'-mono-phosphate conjugated to BSA of all N6-methyladenosine (m6A).

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Target Species:
All species

Form:
Purified

Applications:
Dot Blot, Immunoprecipitation

Clone:
17-3-4-1

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 λ

Img

MilliporeSigma™

MABE1007MI

--


Antigen:
TEL-AML1 fusion

Classification:
Monoclonal

Formulation:
Purified rat monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Immunogen:
KLH-conjugated linear peptide corresponding to human TEL-AML1 fusion.

Quantity:
50 μL

Research Discipline:
Epigenetics and Nuclear Function

Target Species:
Human

Form:
Purified

Applications:
ChIP Assay, Flow Cytometry, Western Blot

Clone:
6F2

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2a κ

Img

MilliporeSigma™

MABE1016MI

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Antigen:
pan-ADP-ribose binding reagent

Classification:
Polyclonal

Formulation:
Purified fromE. coliby Ni-NTA agarose. Supplied in buffer containing 10mM Tris pH 7.5, 0.2M NaCl, 10% Glycerol, 10mM Imidazole, 1mM PMSF, 1mM β-Mercaptoethanol, 10% glycerol without preservatives.

Immunogen:
__

Quantity:
200 μL

Research Discipline:
Epigenetics and Nuclear Function

Target Species:
Human, Mouse

Form:
Purified

Applications:
Dot Blot

Clone:
__

Host Species:
E. coli

Purification Method:
Ni-NTA agarose

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at -80°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -80°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

Isotype:
__

Img

MilliporeSigma™

MABE1025MI

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Antigen:
Tankyrase-2

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Immunogen:
GST-tagged recombinant human Tankyrase-2 fragment from the region between ANK repeats 6 & 8.

Quantity:
100 μg

Research Discipline:
Epigenetics & Nuclear Function

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
2F5.1

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2b κ