MABF836MI
MilliporeSigma™ Mouse anti-EBI3 (Neutralizing), Clone: V1.4H6.25,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF836MI-Each-of-1 | In Stock | ₹ 42,677.33 |
MABF836MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,677.33
GST (18%): ₹ 7,681.919
Total Price: ₹ 50,359.249
Antigen
EBI3 (Neutralizing)
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG3κ in buffer containing PBS without preservatives.
Gene Symbols
Ebi3; Il27b
Immunogen
Recombinant protein corresponding to mouse EBI3/IL-35.
Quantity
100 μg
Research Discipline
Inflammation and Immunology
Gene ID (Entrez)
NP_056581
Content And Storage
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype
IgG3 κ
Applications
Neutralization, Western Blot
Clone
V1.4H6.25
Gene Accession No.
O35228
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Mouse
Form
Purified
Related Products
Description
- Specifically detects EBI3 (Neutralizing) clone: V1.4H6.25 in Mouse samples, and it is validated for Neutralization, Western Blotting EBI3/IL27B is the beta subunit of the functional cytokine IL-27
- The beta subunit is required for activity
- IL-27 is a critical cytokine of mammalian innate immune response
- IL-27 has both pro and anti-inflammatory activities
- IL-27 regulates T-helper cell development and differentiation into TH1, TH2 and TH17 effector cells
- IL-27 also is important in isotype switching for B-cells, and it drives rapid clonal expansion of native but not memory CD4 cells
- IL-27 is also important for its anti-tumor and anti-angiogenic activity on tumor and cancer cells
- The beta subunit EBI3/IL27B is also a component of IL-35 which is a heterodimer of IL-12alpha and IL-27B/EBI3
- IL-35 plays a role in immune suppression
- IL-27 is a secreted cytokine, thus IL-27beta subunit is expressed intracellularly associated with the endoplasmic reticulum and membrane vesicles and is detected extracellularly as part of the mature cytokine as well.
Compare Similar Items
Show Difference
Antigen: EBI3 (Neutralizing)
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG3κ in buffer containing PBS without preservatives.
Gene Symbols: Ebi3; Il27b
Immunogen: Recombinant protein corresponding to mouse EBI3/IL-35.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_056581
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG3 κ
Applications: Neutralization, Western Blot
Clone: V1.4H6.25
Gene Accession No.: O35228
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Purified
Antigen:
EBI3 (Neutralizing)
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG3κ in buffer containing PBS without preservatives.
Gene Symbols:
Ebi3; Il27b
Immunogen:
Recombinant protein corresponding to mouse EBI3/IL-35.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_056581
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG3 κ
Applications:
Neutralization, Western Blot
Clone:
V1.4H6.25
Gene Accession No.:
O35228
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Purified
Antigen: FcgRII/III Anibody
Classification: Monoclonal
Formulation: Purified rat monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl without preservatives.
Gene Symbols: Fcgr3; Fcgr2; Fcgr2b; Ly-17
Immunogen: Whole cells expressing mouse FcgRII/III.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): CD32: NP_034317
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG2a κ
Applications: Functional Assay, Flow Cytometry, Immunocytochemistry
Clone: Ab93
Gene Accession No.: P08508; P08101
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Purified
Antigen:
FcgRII/III Anibody
Classification:
Monoclonal
Formulation:
Purified rat monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl without preservatives.
Gene Symbols:
Fcgr3; Fcgr2; Fcgr2b; Ly-17
Immunogen:
Whole cells expressing mouse FcgRII/III.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
CD32: NP_034317
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG2a κ
Applications:
Functional Assay, Flow Cytometry, Immunocytochemistry
Clone:
Ab93
Gene Accession No.:
P08508; P08101
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Purified
Antigen: Ly-6G (Azide Free)
Classification: Monoclonal
Formulation: Purified rat monoclonal IgG2aκ in buffer containing PBS without preservatives.
Gene Symbols: Ly6g
Immunogen: Propeitary whole cells expressing to mouse Ly-6G.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG2a κ
Applications: Functional Assay
Clone: 1A8
Gene Accession No.: P35461
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Purified
Antigen:
Ly-6G (Azide Free)
Classification:
Monoclonal
Formulation:
Purified rat monoclonal IgG2aκ in buffer containing PBS without preservatives.
Gene Symbols:
Ly6g
Immunogen:
Propeitary whole cells expressing to mouse Ly-6G.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG2a κ
Applications:
Functional Assay
Clone:
1A8
Gene Accession No.:
P35461
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Purified
Antigen: CD122
Classification: Monoclonal
Formulation: Purified rat monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Il2rb
Immunogen: Whole cells corresponding to mouse CD122/IL-2R beta.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_032394
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: 5H4
Gene Accession No.: P16297
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Purified
Antigen:
CD122
Classification:
Monoclonal
Formulation:
Purified rat monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Il2rb
Immunogen:
Whole cells corresponding to mouse CD122/IL-2R beta.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_032394
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
5H4
Gene Accession No.:
P16297
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Purified