MABF848MI
MilliporeSigma™ Mouse anti-EBI3 (Neutralizing), Clone: V1.4C4.22,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF848MI-Each-of-1 | In Stock | ₹ 44,393.20 |
MABF848MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,393.20
GST (18%): ₹ 7,990.776
Total Price: ₹ 52,383.976
Antigen
EBI3 (Neutralizing)
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2bκ in buffer containing PBS without preservatives.
Gene Symbols
Ebi3; Il27b
Immunogen
Recombinant protein corresponding to mouse EBI3/IL-35.
Quantity
100 μg
Research Discipline
Inflammation and Immunology
Gene ID (Entrez)
NP_056581
Content And Storage
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype
IgG2b κ
Applications
Neutralization, Western Blot
Clone
V1.4C4.22
Gene Accession No.
O35228
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Mouse
Form
Purified
Related Products
Description
- Specifically detects EBI3 (Neutralizing) clone: V1.4C4.22 in Mouse samples, and it is validated for Neutralization, Western Blotting EBI3/IL27B is the beta subunit of the functional cytokine IL-27
- The beta subunit is required for activity
- IL-27 is a critical cytokine of mammalian innate immune response
- IL-27 has both pro and anti-inflammatory activities
- IL-27 regulates T-helper cell development and differentiation into TH1, TH2 and TH17 effector cells
- IL-27 also is important in isotype switching for B-cells, and it drives rapid clonal expansion of native but not memory CD4 cells
- IL-27 is also important for its anti-tumor and anti-angiogenic activity on tumor and cancer cells
- The beta subunit EBI3/IL27B is also a component of IL-35 which is a heterodimer of IL-12alpha and IL-27B/EBI3
- IL-35 plays a role in immune suppression
- IL-27 is a secreted cytokine, thus IL-27beta subunit is expressed intracellularly associated with the endoplasmic reticulum and membrane vesicles and is detected extracellularly as part of the mature cytokine as well.
Compare Similar Items
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Antigen: EBI3 (Neutralizing)
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2bκ in buffer containing PBS without preservatives.
Gene Symbols: Ebi3; Il27b
Immunogen: Recombinant protein corresponding to mouse EBI3/IL-35.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_056581
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG2b κ
Applications: Neutralization, Western Blot
Clone: V1.4C4.22
Gene Accession No.: O35228
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Purified
Antigen:
EBI3 (Neutralizing)
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2bκ in buffer containing PBS without preservatives.
Gene Symbols:
Ebi3; Il27b
Immunogen:
Recombinant protein corresponding to mouse EBI3/IL-35.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_056581
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG2b κ
Applications:
Neutralization, Western Blot
Clone:
V1.4C4.22
Gene Accession No.:
O35228
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Purified
Antigen: IDO-1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Ido1, Ido, Indo
Immunogen: KLH-conjugated linear peptide corresponding to the N-terminal region of mouse IDO-1.
Quantity: 100 μg
Research Discipline: Inflammation, Immunology
Gene ID (Entrez): NP_032350
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 4B7
Gene Accession No.: P28776
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Rat
Form: Purified
Antigen:
IDO-1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Ido1, Ido, Indo
Immunogen:
KLH-conjugated linear peptide corresponding to the N-terminal region of mouse IDO-1.
Quantity:
100 μg
Research Discipline:
Inflammation, Immunology
Gene ID (Entrez):
NP_032350
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
4B7
Gene Accession No.:
P28776
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Form:
Purified
Antigen: S100A9
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing PBS without preservatives.
Gene Symbols: S100A9; CAGB; CFAG; MRP14
Immunogen: Recombinant protein corresponding to human S100A9.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_002956
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG1 κ
Applications: ELISA, Western Blot
Clone: 6B4
Gene Accession No.: P06702
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
S100A9
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing PBS without preservatives.
Gene Symbols:
S100A9; CAGB; CFAG; MRP14
Immunogen:
Recombinant protein corresponding to human S100A9.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_002956
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG1 κ
Applications:
ELISA, Western Blot
Clone:
6B4
Gene Accession No.:
P06702
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: CAP-18/CAMP
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CAMP; CAP18; FALL39; HSD26; LL37
Immunogen: Human cytochrome b preparation containing co-purified hCAP-18.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_034051
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: H7
Gene Accession No.: P49913
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
CAP-18/CAMP
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CAMP; CAP18; FALL39; HSD26; LL37
Immunogen:
Human cytochrome b preparation containing co-purified hCAP-18.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_034051
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
H7
Gene Accession No.:
P49913
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified