MABF848MI

MilliporeSigma™ Mouse anti-EBI3 (Neutralizing), Clone: V1.4C4.22,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABF848MI-Each-of-1 In Stock ₹ 42,677.33

MABF848MI - Each of 1

₹ 42,677.33

In Stock

Quantity

1

Base Price: ₹ 42,677.33

GST (18%): ₹ 7,681.919

Total Price: ₹ 50,359.249

Antigen

EBI3 (Neutralizing)

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG2bκ in buffer containing PBS without preservatives.

Gene Symbols

Ebi3; Il27b

Immunogen

Recombinant protein corresponding to mouse EBI3/IL-35.

Quantity

100 μg

Research Discipline

Inflammation and Immunology

Gene ID (Entrez)

NP_056581

Content And Storage

Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

Isotype

IgG2b κ

Applications

Neutralization, Western Blot

Clone

V1.4C4.22

Gene Accession No.

O35228

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Mouse

Form

Purified

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Description

  • Specifically detects EBI3 (Neutralizing) clone: V1.4C4.22 in Mouse samples, and it is validated for Neutralization, Western Blotting EBI3/IL27B is the beta subunit of the functional cytokine IL-27
  • The beta subunit is required for activity
  • IL-27 is a critical cytokine of mammalian innate immune response
  • IL-27 has both pro and anti-inflammatory activities
  • IL-27 regulates T-helper cell development and differentiation into TH1, TH2 and TH17 effector cells
  • IL-27 also is important in isotype switching for B-cells, and it drives rapid clonal expansion of native but not memory CD4 cells
  • IL-27 is also important for its anti-tumor and anti-angiogenic activity on tumor and cancer cells
  • The beta subunit EBI3/IL27B is also a component of IL-35 which is a heterodimer of IL-12alpha and IL-27B/EBI3
  • IL-35 plays a role in immune suppression
  • IL-27 is a secreted cytokine, thus IL-27beta subunit is expressed intracellularly associated with the endoplasmic reticulum and membrane vesicles and is detected extracellularly as part of the mature cytokine as well.

Compare Similar Items

Show Difference

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MilliporeSigma™

MABF848MI

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Antigen:
EBI3 (Neutralizing)

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2bκ in buffer containing PBS without preservatives.

Gene Symbols:
Ebi3; Il27b

Immunogen:
Recombinant protein corresponding to mouse EBI3/IL-35.

Quantity:
100 μg

Research Discipline:
Inflammation and Immunology

Gene ID (Entrez):
NP_056581

Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

Isotype:
IgG2b κ

Applications:
Neutralization, Western Blot

Clone:
V1.4C4.22

Gene Accession No.:
O35228

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified

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MABF850MI

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Antigen:
IDO-1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Ido1, Ido, Indo

Immunogen:
KLH-conjugated linear peptide corresponding to the N-terminal region of mouse IDO-1.

Quantity:
100 μg

Research Discipline:
Inflammation, Immunology

Gene ID (Entrez):
NP_032350

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
4B7

Gene Accession No.:
P28776

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Form:
Purified

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MilliporeSigma™

MABF854MI

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Antigen:
S100A9

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing PBS without preservatives.

Gene Symbols:
S100A9; CAGB; CFAG; MRP14

Immunogen:
Recombinant protein corresponding to human S100A9.

Quantity:
100 μg

Research Discipline:
Inflammation and Immunology

Gene ID (Entrez):
NP_002956

Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.

Isotype:
IgG1 κ

Applications:
ELISA, Western Blot

Clone:
6B4

Gene Accession No.:
P06702

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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Antigen:
CAP-18/CAMP

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
CAMP; CAP18; FALL39; HSD26; LL37

Immunogen:
Human cytochrome b preparation containing co-purified hCAP-18.

Quantity:
100 μg

Research Discipline:
Inflammation and Immunology

Gene ID (Entrez):
NP_034051

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
H7

Gene Accession No.:
P49913

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified