MABS1329
MilliporeSigma™ Annexin A3, Mouse, Unlabeled, Clone: 9996-1-3M1/3L7-5,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1329-Each-of-1 | In Stock | ₹ 40,197.80 |
MABS1329 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,197.80
GST (18%): ₹ 7,235.604
Total Price: ₹ 47,433.404
Antigen
Annexin A3
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG1 in Tris-buffered saline (TBS) containing 50mM tris-HCl (pH7.5) and 150mM NaCl without preservatives.
Gene Accession No.
P12429
Immunogen
Recombinant human annexin A3.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_005130
Target Species
Human
Form
Purified
Applications
Neutralization, Western Blot
Clone
9996-1-3M1/3L7-5
Conjugate
Unconjugated
Gene
ANXA3, ANX3
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This monoclonal antibody detected a single ∽33 kDa target band among a panel of human hepatocellular carcinoma (HCC) cell lines. The epitope has been mapped to a 10-a.a. region within the third annexin domain (Tong, M., et al. (2015). Stem Cell Reports. 5(1):45-59).
Content And Storage
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype
IgG1 κ
Related Products
Description
- Annexin A3 (UniProt P12429; also known as 35-alpha calcimedin, Annexin III, Annexin-3, Inositol 1,2-cyclic phosphate 2-phosphohydrolase, Lipocortin III, PAP-III, Placental anticoagulant protein III) is encoded by the ANXA3 (also known as ANX3) gene (Gene ID 306) in human
- Annexin A3 is a Ca2+-dependent phospholipid-binding protein shown to promote angiogenesis and rat liver regeneration
- Upregulated annexin A3 expression is reported in ovarian, breast, colon, lung, gastric, gallbladder, testicular, and urothelial cancers, where it is involved in promoting tumorigenesis and resistance to chemotherapy
- ANXA3 is reported to represent the most significantly upregulated gene that encodes for a secretory protein in the CD133+ liver cancer stem cell (CSC) subset
- Both cellular and secretory annexin A3 play pivotal roles in promoting cancer and stem cell-like features in CD133+ liver CSCs through a dysregulated JNK pathway
- Annexin A3 serum levels in hepatocellular carcinoma (HCC) patients are closely associated with aggressive clinical features
- Annexin A3 neutralizing antibody is shown to cause a significant reduction in HCC tumor growth and self-renewal by effectively killing off CD133+ CSCs both in cultures in vitro and in animal xenograft in vivo.
Compare Similar Items
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Antigen: Annexin A3
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG1 in Tris-buffered saline (TBS) containing 50mM tris-HCl (pH7.5) and 150mM NaCl without preservatives.
Gene Accession No.: P12429
Immunogen: Recombinant human annexin A3.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_005130
Target Species: Human
Form: Purified
Applications: Neutralization, Western Blot
Clone: 9996-1-3M1/3L7-5
Conjugate: Unconjugated
Gene: ANXA3, ANX3
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody detected a single ∽33 kDa target band among a panel of human hepatocellular carcinoma (HCC) cell lines. The epitope has been mapped to a 10-a.a. region within the third annexin domain (Tong, M., et al. (2015). Stem Cell Reports. 5(1):45-59).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG1 κ
Antigen:
Annexin A3
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG1 in Tris-buffered saline (TBS) containing 50mM tris-HCl (pH7.5) and 150mM NaCl without preservatives.
Gene Accession No.:
P12429
Immunogen:
Recombinant human annexin A3.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_005130
Target Species:
Human
Form:
Purified
Applications:
Neutralization, Western Blot
Clone:
9996-1-3M1/3L7-5
Conjugate:
Unconjugated
Gene:
ANXA3, ANX3
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody detected a single ∽33 kDa target band among a panel of human hepatocellular carcinoma (HCC) cell lines. The epitope has been mapped to a 10-a.a. region within the third annexin domain (Tong, M., et al. (2015). Stem Cell Reports. 5(1):45-59).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG1 κ
Antigen: GLUT1 (CT)
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: NP_006507
Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of human GLUT1.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Rat
Form: Purified
Applications: Immunohistochemistry, Western Blot
Clone: 5B12.3
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Antigen:
GLUT1 (CT)
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
NP_006507
Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminus of human GLUT1.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Rat
Form:
Purified
Applications:
Immunohistochemistry, Western Blot
Clone:
5B12.3
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Antigen: DUX4
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q9UBX2
Immunogen: GST-tagged recombinant human DUX4 C-terminal fragment.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_001292997
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: P4H2
Conjugate: Unconjugated
Gene: DUX4, DUX10
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone P4H2 is specific to DUX4 (UniProt Q9UBX2) and does not recognize DUX4c (DUX4L9; UniProt Q6RFH8) or the spliced DUX4 short isoform DUX4-s (UniProt E2JJS1) that lacks the C-terminal epitope region targeted by clone P4H2 (Geng, L.N., et al. (2011). Hybridoma (Larchmt). 30(2):125-130; Snider, L., et al. (2010). PLoS Genet. 6(10):e1001181).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
DUX4
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q9UBX2
Immunogen:
GST-tagged recombinant human DUX4 C-terminal fragment.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001292997
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
P4H2
Conjugate:
Unconjugated
Gene:
DUX4, DUX10
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone P4H2 is specific to DUX4 (UniProt Q9UBX2) and does not recognize DUX4c (DUX4L9; UniProt Q6RFH8) or the spliced DUX4 short isoform DUX4-s (UniProt E2JJS1) that lacks the C-terminal epitope region targeted by clone P4H2 (Geng, L.N., et al. (2011). Hybridoma (Larchmt). 30(2):125-130; Snider, L., et al. (2010). PLoS Genet. 6(10):e1001181).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__