MABT533
MilliporeSigma™ PECAM-1, Mouse, Unlabeled, Clone: 4A8.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT533-Each-of-1 | In Stock | ₹ 42,677.33 |
MABT533 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,677.33
GST (18%): ₹ 7,681.919
Total Price: ₹ 50,359.249
Antigen
PECAM-1
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P16284
Immunogen
GST-tagged recombinant human PECAM-1 cytoplasmic domain.
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_000433
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
4A8.1
Conjugate
Unconjugated
Gene
PECAM1
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 4A8.1 was raised against the cytoplasmic domain of PECAM-1 (CD31) isoform Long. Reactivity toward spliced isoforms Delta12, Delta13, Delta14, Delta14-15, and Delta15 with various cytomplasmic domain deletions is possible, but has not not been confirmed.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- Platelet endothelial cell adhesion molecule (UniProt P16284; also known as CD31, EndoCAM, GPIIA′, PECA1, PECAM-1) is encoded by the PECAM1 gene (Gene ID 5175) in human
- PECAM-1 (CD31) is a 130kDa cell adhesion molecule that is expressed at the junctions of all continuous endothelia, as well as most bone marrow-derived hematopoietic cells, including platelets, monocytes, granulocytes and some lymphocytes
- The human PECAM1 and murine Pecam1 genes both produce multiple spliced isoforms with varying lengths in cytoplasmic domain, with the isoform Long being the major form expressed in human tissues and endothelial cells (ECs), and isoform delta 14-15 being the predominantly expressed murine form
- PECAM-1 plays an import role in maintaining vascular integrity and function by mediating ECs interactions with pericytes and smooth muscle cells (SMCs)
- PECAM-1 is initially produced with a signal peptide (human a.a
- 1-27, murine a.a
- 1-17) sequence, the removal of which yields the mature protein with a large extracellular region (human a.a
- 28-601, mouse a.a
- 18-590) composed of six C2-type Ig-like domains, followed by a transmembrane seqment (human a.a
- 602-620, mouse a.a
- 591-609) and a cytoplasmic tail (human a.a
- 621-738, mouse a.a
- 610-727) that plays an essential role in PECAM-1-mediated cellular signaling.
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Antigen: PECAM-1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P16284
Immunogen: GST-tagged recombinant human PECAM-1 cytoplasmic domain.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_000433
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 4A8.1
Conjugate: Unconjugated
Gene: PECAM1
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 4A8.1 was raised against the cytoplasmic domain of PECAM-1 (CD31) isoform Long. Reactivity toward spliced isoforms Delta12, Delta13, Delta14, Delta14-15, and Delta15 with various cytomplasmic domain deletions is possible, but has not not been confirmed.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
PECAM-1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P16284
Immunogen:
GST-tagged recombinant human PECAM-1 cytoplasmic domain.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_000433
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
4A8.1
Conjugate:
Unconjugated
Gene:
PECAM1
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 4A8.1 was raised against the cytoplasmic domain of PECAM-1 (CD31) isoform Long. Reactivity toward spliced isoforms Delta12, Delta13, Delta14, Delta14-15, and Delta15 with various cytomplasmic domain deletions is possible, but has not not been confirmed.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: Desmin
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: GST/His-taged recombinant fragment corresponding to 64 amino acids from the C-terminal region of human Desmin.
Quantity: 25 μg
Research Discipline: Cell Structure
Gene ID (Entrez): __
Target Species: Rat, Mouse, Human
Form: Purified
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 4C12.1
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 4C12.1 specifically detects Desmin in human, mouse, and rat muscles. It targets an epitope within 64 amino acids from the C-terminal end.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
Desmin
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
GST/His-taged recombinant fragment corresponding to 64 amino acids from the C-terminal region of human Desmin.
Quantity:
25 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
__
Target Species:
Rat, Mouse, Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
4C12.1
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 4C12.1 specifically detects Desmin in human, mouse, and rat muscles. It targets an epitope within 64 amino acids from the C-terminal end.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ
Antigen: Desmin
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: GST/His-taged recombinant fragment corresponding to 64 amino acids from the C-terminal region of human Desmin.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001918
Target Species: Human, Rat, Mouse
Form: Purified
Applications: Western Blot, Immunohistochemistry (Paraffin)
Clone: 4C12.1
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 4C12.1 specifically detects Desmin in human, mouse, and rat muscles. It targets an epitope within 64 amino acids from the C-terminal end.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
Desmin
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
GST/His-taged recombinant fragment corresponding to 64 amino acids from the C-terminal region of human Desmin.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001918
Target Species:
Human, Rat, Mouse
Form:
Purified
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Clone:
4C12.1
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 4C12.1 specifically detects Desmin in human, mouse, and rat muscles. It targets an epitope within 64 amino acids from the C-terminal end.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ
Antigen: Lamin A and C
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: GST/His-tagged recombinant fragment corresponding to 148 amino acids from the internal region of rat Lamin A/C.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001002016
Target Species: Human, Rat
Form: Purified
Applications: Western Blot, Immunohistochemistry (Paraffin)
Clone: 2F4.1
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 2F4.1 detects Lamin A/C in human and rat tissues. It targets an epitope within 148 amino acids from the internal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
Lamin A and C
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
GST/His-tagged recombinant fragment corresponding to 148 amino acids from the internal region of rat Lamin A/C.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001002016
Target Species:
Human, Rat
Form:
Purified
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Clone:
2F4.1
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 2F4.1 detects Lamin A/C in human and rat tissues. It targets an epitope within 148 amino acids from the internal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ