MABC1207
MilliporeSigma™ CIRP (CIRBP), Mouse, Unlabeled, Clone: 6C7.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABC1207-Each-of-1 | In Stock | ₹ 44,990.87 |
MABC1207 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,990.87
GST (18%): ₹ 8,098.357
Total Price: ₹ 53,089.227
Antigen
CIRP (CIRBP)
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q14011
Immunogen
GST-tagged recombinant human CIRP (CIRBP) internal fragment.
Quantity
100 μL
Research Discipline
Apoptosis & Cancer
Gene ID (Entrez)
NP_001271
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
6C7.1
Conjugate
Unconjugated
Gene
CIRBP, A18HNRNP, CIRP
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 6C7.1 is expected to recognize CIRP spliced isoforms 1 and 3 (UniProt Q14011). Cross-reactivity toward spliced isoform 2 is possible, but has not been confirmed.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- Cold-inducible RNA-binding protein (UniProt Q14011; also known as A18 hnRNP, Glycine-rich RNA-binding protein CIRP) is encoded by the CIRBP (also known as A18HNRNP, CIRP) gene (Gene ID 1153) in human
- CIRP is an 18kDa RNA-binding protein with an RNA recognition motif (RRM; a.a
- 6-84) and a glycine-rich domain (a.a
- 92-158)
- CIRP migrates from nucleus to cytoplasm, where it mediates posttranscriptional regulation of target mRNAs
- Originally characterized and named as a cold-induced protein, CIRP exerts antiapoptotic and cell-protective effects in response to cold stress, as well as other stimuli such as UV irradiation and hypoxia
- CIRP is expressed in a broad range of tissues (e.g
- testis, brain, lung, kidney, liver, stomach, bone marrow, and heart) and upregulated CIRP levels have been reported in several types of cancers
- CIRP knockdown is reported to increase p53 level and enhance cancer cells chemo-sensitivity to DNA damage inducing drugs
- Likewise, CIRP overexpression results in p53 downregulation.
Compare Similar Items
Show Difference
Antigen: CIRP (CIRBP)
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q14011
Immunogen: GST-tagged recombinant human CIRP (CIRBP) internal fragment.
Quantity: 100 μL
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_001271
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 6C7.1
Conjugate: Unconjugated
Gene: CIRBP, A18HNRNP, CIRP
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 6C7.1 is expected to recognize CIRP spliced isoforms 1 and 3 (UniProt Q14011). Cross-reactivity toward spliced isoform 2 is possible, but has not been confirmed.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
CIRP (CIRBP)
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q14011
Immunogen:
GST-tagged recombinant human CIRP (CIRBP) internal fragment.
Quantity:
100 μL
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_001271
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
6C7.1
Conjugate:
Unconjugated
Gene:
CIRBP, A18HNRNP, CIRP
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 6C7.1 is expected to recognize CIRP spliced isoforms 1 and 3 (UniProt Q14011). Cross-reactivity toward spliced isoform 2 is possible, but has not been confirmed.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: Sorting Nexin-17
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q15036
Immunogen: GST-tagged recombinant fragment from the FERM-like region of human Sorting Nexin-17.
Quantity: 100 μg
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_001253989
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 4B8.1
Conjugate: Unconjugated
Gene: SNX17, KIAA0064
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 4B8.1 recognizes an internal epitope within the FERM-like region present in both spliced isoforms of human sorting nexin-17 reported by UniProt (Q15036).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
Sorting Nexin-17
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q15036
Immunogen:
GST-tagged recombinant fragment from the FERM-like region of human Sorting Nexin-17.
Quantity:
100 μg
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_001253989
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
4B8.1
Conjugate:
Unconjugated
Gene:
SNX17, KIAA0064
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 4B8.1 recognizes an internal epitope within the FERM-like region present in both spliced isoforms of human sorting nexin-17 reported by UniProt (Q15036).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2b κ
Antigen: RGS2
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: GST/His-tagged recombinant fragment corresponding to 82 amino acids from the N-terminal region of human Regulator of G-protein signaling 2 (RGS2).
Quantity: 25 μg
Research Discipline: Apoptosis and Cancer
Gene ID (Entrez): __
Target Species: Human, Rat
Form: Purified
Applications: Western Blot, Immunohistochemistry (Paraffin)
Clone: __
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 9D9.1 specifically detects Regulator of G-protein signaling 2 (RGS2) in human and rat cells. It targets an epitope within 82 amino acids from the N-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2a
Antigen:
RGS2
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
GST/His-tagged recombinant fragment corresponding to 82 amino acids from the N-terminal region of human Regulator of G-protein signaling 2 (RGS2).
Quantity:
25 μg
Research Discipline:
Apoptosis and Cancer
Gene ID (Entrez):
__
Target Species:
Human, Rat
Form:
Purified
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Clone:
__
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 9D9.1 specifically detects Regulator of G-protein signaling 2 (RGS2) in human and rat cells. It targets an epitope within 82 amino acids from the N-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2a
Antigen: Ephrin-B2
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Gene Accession No.: NP_004084
Immunogen: KLH-conjugated linear peptide corresponding to human Ephrin-B2.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Immunohistochemistry, Western Blot
Clone: 10H1.1
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Purified by ion-exchange chromatography
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgM κ
Antigen:
Ephrin-B2
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Gene Accession No.:
NP_004084
Immunogen:
KLH-conjugated linear peptide corresponding to human Ephrin-B2.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Immunohistochemistry, Western Blot
Clone:
10H1.1
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Purified by ion-exchange chromatography
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgM κ