MABS1713MI
MilliporeSigma™ Synaptotagmin-like Protein 4 (SYTL4), Mouse, Unlabeled, Clone: 7D2.2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1713MI-Each-of-1 | In Stock | ₹ 37,453.03 |
MABS1713MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,453.03
GST (18%): ₹ 6,741.545
Total Price: ₹ 44,194.575
Antigen
Synaptotagmin-like Protein 4 (SYTL4)
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q96C24
Immunogen
GST-tagged recombinant human synaptotagmin-like protein 4 (SYTL4) internal fragment.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_001123368
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
7D2.2
Conjugate
Unconjugated
Gene
SYTL4, SLP4
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 7D2.2 epitope resides within an internal region mostly missing in human spliced isoform 2. Reactivity toward isoform 2 has not been confirmed.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG2a κ
Related Products
Description
- Synaptotagmin-like protein 4 (UniProt Q96C24; also known as Exophilin-2, Granuphilin) is encoded by the SYTL4 (also known as SLP4) gene (Gene ID 94121) in human
- SYLT4 belongs to the synaptotagmin-like protein family, which contains an N-terminal RabBD (Rab-binding) domain and two C-terminal C2 domains
- The characteristic feature of this family is the N-terminal domain, which is not found in other C-type tandem C2 proteins
- SYLT4 is detected close to the plasma membrane and on secretory granules
- Interacts with vesicles containing negatively charged phospholipids in a Ca2+-independent manner
- It can bind to both the GTP- and GDP-bound forms of Rab27A and inhibits a specific GTP/GDP exchange cycle required for dense-core vesicle exocytosis
- It is the first regulatory in the exocytosis pathway that functions by directly connecting Rab and SNARE
- It modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary
- It is not only essential for the docking of insulin granules, but also simultaneously imposes a fusion constraint on them through an interaction with syntaxin-1alpha fusion machinery.
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Antigen: Synaptotagmin-like Protein 4 (SYTL4)
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q96C24
Immunogen: GST-tagged recombinant human synaptotagmin-like protein 4 (SYTL4) internal fragment.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_001123368
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 7D2.2
Conjugate: Unconjugated
Gene: SYTL4, SLP4
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 7D2.2 epitope resides within an internal region mostly missing in human spliced isoform 2. Reactivity toward isoform 2 has not been confirmed.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
Synaptotagmin-like Protein 4 (SYTL4)
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q96C24
Immunogen:
GST-tagged recombinant human synaptotagmin-like protein 4 (SYTL4) internal fragment.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001123368
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
7D2.2
Conjugate:
Unconjugated
Gene:
SYTL4, SLP4
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 7D2.2 epitope resides within an internal region mostly missing in human spliced isoform 2. Reactivity toward isoform 2 has not been confirmed.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: TMEM64
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q6YI46
Immunogen: KLH-conjugated linear peptide corresponding to the C-terminal end sequence of human and rat TMEM64.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_001008495
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 7A2.1
Conjugate: Unconjugated
Gene: TMEM64
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: The immunogen sequence is 100% conserved between human and rat species and present in all four human spliced isoforms reported by UniProt (Q6YI46 & D3ZV19). Murine cross-reactivity is highly likely, but has not been confirmed.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
TMEM64
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q6YI46
Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminal end sequence of human and rat TMEM64.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001008495
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
7A2.1
Conjugate:
Unconjugated
Gene:
TMEM64
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
The immunogen sequence is 100% conserved between human and rat species and present in all four human spliced isoforms reported by UniProt (Q6YI46 & D3ZV19). Murine cross-reactivity is highly likely, but has not been confirmed.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: Potassium Channel Kir3.4
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P48544
Immunogen: GST-tagged human potassium channel Kir3.4 C-terminal end fragment.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_000881
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 8F4.1
Conjugate: Unconjugated
Gene: KCNJ5, GIRK4, LQT13
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 8F4.1 detects human potassium channel Kir3.4 by targeting an epitope within the C-terminal cytoplasmic domain.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
Potassium Channel Kir3.4
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P48544
Immunogen:
GST-tagged human potassium channel Kir3.4 C-terminal end fragment.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000881
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
8F4.1
Conjugate:
Unconjugated
Gene:
KCNJ5, GIRK4, LQT13
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 8F4.1 detects human potassium channel Kir3.4 by targeting an epitope within the C-terminal cytoplasmic domain.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
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