MABT886
MilliporeSigma™ Rabbit anti-VE-Cadherin, Clone: Vli37,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT886-Each-of-1 | In Stock | ₹ 38,734.72 |
MABT886 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
VE-Cadherin
Classification
Monoclonal
Formulation
Rabbit monoclonal IgG in supernatant with 0.05% sodium azide.
Gene Symbols
Cdh5
Immunogen
Linear peptide corresponding to the C-terminal cytoplasmic domain sequence of mouse VE-Cadherin.
Quantity
100 μL
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_033998.2
Content And Storage
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
Vli37
Gene Accession No.
P55284
Host Species
Rabbit
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Bovine, Mouse
Form
Supernatant
Related Products
Description
- Specifically detects VE-Cadherin clone: Vli37 in Bovine, Mouse samples, and it is validated for Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blotting Cadherin-5 (UniProt P55284; also known as Vascular endothelial cadherin, VE-Cad, VE-cadherin, VEcad, CD144) is encoded by the Cdh5 gene (Gene ID 12562) in murine species
- Cadherins (calcium-dependent adhesion) are type-1 transmembrane proteins that form adherens junctions in tissues and play important roles in mediating cell adhesion
- Cadherins are designated with a prefix that specifies their tissue association
- Vascular endothelial-cadherin (VE-cadherin) is the transmembrane component of the endothelial adherens junction between vascular endothelial cells (ECs) and plays a pivotal role in endothelium integrity and in the control of vascular permeability
- One characteristic of VEGF-induced vascular permeability is the phosphorylation of VE-cadherin, which leads to VE-cadherin internalization and the destabilization of adherens junctions
- Likewise, VE-cadherin overexpression is shown to decrease the permeability of endothelial monolayers in vitro
- VE-cadherin is initially produced with a signal peptide (a.a
- 1-24) and a propeptide (a.a
- 25-45) sequence, the removal of which yields tthe mature protein containing a large extracellular region (a.a
- 46-599) with five cadherine repeats (a.a
- 46-149, 150-256, 257-371, 372-476, 477-593), followed by a transmembrane segment (a.a
- 600-620) and a cytoplasmic domain (a.a
- 621-784).
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Antigen: VE-Cadherin
Classification: Monoclonal
Formulation: Rabbit monoclonal IgG in supernatant with 0.05% sodium azide.
Gene Symbols: Cdh5
Immunogen: Linear peptide corresponding to the C-terminal cytoplasmic domain sequence of mouse VE-Cadherin.
Quantity: 100 μL
Research Discipline: Cell Structure
Gene ID (Entrez): NP_033998.2
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: Vli37
Gene Accession No.: P55284
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Bovine, Mouse
Form: Supernatant
Antigen:
VE-Cadherin
Classification:
Monoclonal
Formulation:
Rabbit monoclonal IgG in supernatant with 0.05% sodium azide.
Gene Symbols:
Cdh5
Immunogen:
Linear peptide corresponding to the C-terminal cytoplasmic domain sequence of mouse VE-Cadherin.
Quantity:
100 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_033998.2
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
Vli37
Gene Accession No.:
P55284
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Bovine, Mouse
Form:
Supernatant
Antigen: PL Scramblase 1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Plscr1, Tra1b, Tras1
Immunogen: Recombinant protein corresponding to the cytoplasmic domain of mouse PL Scramblase 1.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_035766
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Western Blot
Clone: 9A7
Gene Accession No.: Q9JJ00
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Purified
Antigen:
PL Scramblase 1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Plscr1, Tra1b, Tras1
Immunogen:
Recombinant protein corresponding to the cytoplasmic domain of mouse PL Scramblase 1.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_035766
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
9A7
Gene Accession No.:
Q9JJ00
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Purified
Antigen: CTHRC1
Classification: Monoclonal
Formulation: Purified rabbit monoclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CTHRC1; UNQ762; PRO1550
Immunogen: Linear peptide corresponding to a C-terminal sequence of human CTHRC1.
Quantity: 200 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_612464.1
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: __
Applications: Immunohistochemistry, Western Blot
Clone: Vli-55
Gene Accession No.: Q96CG8
Host Species: Rabbit
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine, Rat
Form: Purified
Antigen:
CTHRC1
Classification:
Monoclonal
Formulation:
Purified rabbit monoclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CTHRC1; UNQ762; PRO1550
Immunogen:
Linear peptide corresponding to a C-terminal sequence of human CTHRC1.
Quantity:
200 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_612464.1
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
__
Applications:
Immunohistochemistry, Western Blot
Clone:
Vli-55
Gene Accession No.:
Q96CG8
Host Species:
Rabbit
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine, Rat
Form:
Purified
Antigen: Platelet
Classification: Monoclonal
Formulation: Purified mouse monoclonal antibody IgM in PBS with 0.05% sodium azide.
Gene Symbols: ITGA2B;GP2B;ITGAB
Immunogen: Platelets obtained from the blood of a patient with Glanzmann's thrombasthenia.
Quantity: 25 μL
Research Discipline: Cell Structure
Gene ID (Entrez): __
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgM
Applications: Dot Blot, ELISA, Flow Cytometry, Radioimmune Assays (RIA), Western Blot
Clone: PAC-1
Gene Accession No.: __
Host Species: Mouse
Purification Method: Purified by ion-exchange chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Platelet
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal antibody IgM in PBS with 0.05% sodium azide.
Gene Symbols:
ITGA2B;GP2B;ITGAB
Immunogen:
Platelets obtained from the blood of a patient with Glanzmann's thrombasthenia.
Quantity:
25 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
__
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgM
Applications:
Dot Blot, ELISA, Flow Cytometry, Radioimmune Assays (RIA), Western Blot
Clone:
PAC-1
Gene Accession No.:
__
Host Species:
Mouse
Purification Method:
Purified by ion-exchange chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified