MABT887MI
MilliporeSigma™ anti-PL Scramblase 1 Clone: 9A7,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT887MI-Each-of-1 | In Stock | ₹ 44,990.87 |
MABT887MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,990.87
GST (18%): ₹ 8,098.357
Total Price: ₹ 53,089.227
Antigen
PL Scramblase 1
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
Q9JJ00
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 9A7 reacts with murine PL Scramblase 1, and does not cross-reacts with murine PL Scramblase 2/3/4 or human PL Scramblase 1.
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG1 κ
Applications
Western Blot
Clone
9A7
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
Plscr1, Tra1b, Tras1
Immunogen
Recombinant protein corresponding to the cytoplasmic domain of mouse PL Scramblase 1.
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_035766
Target Species
Mouse
Form
Purified
Related Products
Description
- Specifically detects PL Scramblase 1 Clone: 9A7 in Mouse samples, and it is validated for Western Blotting Phospholipid scramblase 1 (UniProt Q9JJ00; also known as Ca(2+)-dependent phospholipid scramblase 1, Nor1, PL scramblase 1, Tra1, Transplantability-associated protein 1) is encoded by the Plscr1 (also known as Tra1b, Tras1) gene (Gene ID 22038) in murine species
- Plasma membrane phospholipids are distributed asymmetrically between the inner and outer leaflets
- Such asymmetrical distribution collapses in response to blood coagulation and apoptosis, resulting in phospholipid 'scrambling' between the two leaflets of the plasma membrane
- Flippases, floppases, and scramblases are three types enzymes known to mediate transbilayer lipid motion
- Flippases and floppases function via ATP-dependent mechanism, while scramblases mediate transbilayer movement in a non-selective and energy-independent manner
- Originally identified in 1996 as a 37kDa erythrocyte type II transmembrane protein that mediates calcium-dependent membrane phospholipids redistribution, PL Scramblase 1 is the protein product encoded by the founding member of the PLSCR family of genes (PLSCR1-5)
- All PLSCR family members, with the exception of PLSCR2, possess a proline-rich N-terminal region containing PxxP and PPxY domains, a cysteine-rich region, a conserved calcium-binding domain (EF-hand-like), and a putative transmembrane region enriched in hydrophobic amino acids
- In addition, PLSCR1 contains a nuclear localization signal (NLS) and a DNA-binding domain that are essential for its nuclear localization and associated nuclear function
- In addition to PLSCRs, TMEM16 and XKR family members have also been reported to mediate scramblase activity.
Compare Similar Items
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Antigen: PL Scramblase 1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q9JJ00
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 9A7 reacts with murine PL Scramblase 1, and does not cross-reacts with murine PL Scramblase 2/3/4 or human PL Scramblase 1.
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Western Blot
Clone: 9A7
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Plscr1, Tra1b, Tras1
Immunogen: Recombinant protein corresponding to the cytoplasmic domain of mouse PL Scramblase 1.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_035766
Target Species: Mouse
Form: Purified
Antigen:
PL Scramblase 1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q9JJ00
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 9A7 reacts with murine PL Scramblase 1, and does not cross-reacts with murine PL Scramblase 2/3/4 or human PL Scramblase 1.
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
9A7
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Plscr1, Tra1b, Tras1
Immunogen:
Recombinant protein corresponding to the cytoplasmic domain of mouse PL Scramblase 1.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_035766
Target Species:
Mouse
Form:
Purified
Antigen: CTHRC1
Classification: Monoclonal
Conjugate: __
Gene Accession No.: Q96CG8
Host Species: Rabbit
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: __
Applications: Immunohistochemistry, Western Blot
Clone: Vli-55
Formulation: Purified rabbit monoclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CTHRC1; UNQ762; PRO1550
Immunogen: Linear peptide corresponding to a C-terminal sequence of human CTHRC1.
Quantity: 200 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_612464.1
Target Species: Human, Mouse, Porcine, Rat
Form: Purified
Antigen:
CTHRC1
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
Q96CG8
Host Species:
Rabbit
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
__
Applications:
Immunohistochemistry, Western Blot
Clone:
Vli-55
Formulation:
Purified rabbit monoclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CTHRC1; UNQ762; PRO1550
Immunogen:
Linear peptide corresponding to a C-terminal sequence of human CTHRC1.
Quantity:
200 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_612464.1
Target Species:
Human, Mouse, Porcine, Rat
Form:
Purified
Antigen: Platelet
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Mouse
Purification Method: Purified by ion-exchange chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone PAC-1 is a pentameric IgM that binds to the activated platelets, but not to unstimulated platelets.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgM
Applications: Dot Blot, ELISA, Flow Cytometry, Radioimmune Assays (RIA), Western Blot
Clone: PAC-1
Formulation: Purified mouse monoclonal antibody IgM in PBS with 0.05% sodium azide.
Gene Symbols: ITGA2B;GP2B;ITGAB
Immunogen: Platelets obtained from the blood of a patient with Glanzmann's thrombasthenia.
Quantity: 25 μL
Research Discipline: Cell Structure
Gene ID (Entrez): __
Target Species: Human
Form: Purified
Antigen:
Platelet
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Mouse
Purification Method:
Purified by ion-exchange chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone PAC-1 is a pentameric IgM that binds to the activated platelets, but not to unstimulated platelets.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgM
Applications:
Dot Blot, ELISA, Flow Cytometry, Radioimmune Assays (RIA), Western Blot
Clone:
PAC-1
Formulation:
Purified mouse monoclonal antibody IgM in PBS with 0.05% sodium azide.
Gene Symbols:
ITGA2B;GP2B;ITGAB
Immunogen:
Platelets obtained from the blood of a patient with Glanzmann's thrombasthenia.
Quantity:
25 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
__
Target Species:
Human
Form:
Purified
Antigen: __
Classification: __
Conjugate: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Applications: __
Clone: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene Accession No.:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__
Applications:
__
Clone:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__