NA29100UG
MilliporeSigma™ anti-p16 Clone: DCS-50.1/H4,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NA29100UG-Each-of-1 | In Stock | ₹ 45,464.76 |
NA29100UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,464.76
GST (18%): ₹ 8,183.657
Total Price: ₹ 53,648.417
Antigen
p16
Classification
Monoclonal
Conjugate
Unconjugated
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Applications
Immunoblot
Clone
DCS-50.1/H4
Formulation
In 0.05M sodium phosphate buffer, 0.2% gelatin pH 7.5.
Immunogen
recombinant, human p16
Regulatory Status
RUO
Test Specificity
Recognizes the ∽16kDa p16 protein in Saos-2 cells and bladder tissue. Sold under license of U.S. Patent 6,482,929. Sold under license of U.S. Patent 5,843,756, 6,090,578, and corresponding patents.
Content And Storage
2°C to 8°C
Isotype
IgG1
Related Products
Description
- Specifically detects p16 Clone: DCS-50.1/H4 in Human samples, and it is validated for Immuno Blotting Various cyclin dependent kinases (CDKs) are critical for progression through the G1 phase of the cell cycle, and the enzymatic activity of CDKs is dependent upon specific association with G1 cyclins
- The active cyclin/CDK complex can be inhibited by a number of different inhibitor proteins including the p16 product of the Multiple Tumor Suppressor 1 gene (MTS1)
- p16 was initially identified as a component of cyclin/CDK complexes and shown to specifically inhibit CDK4, thus earning the name p16 INK4
- Independent studies have demonstrated that the gene encoding p16 is commonly deleted in many different tumor cell lines
- Recent evidence implicates the p16 protein in the Retinoblastoma pathway for control of cell growth and proliferation and demonstrates that p16 can function as a tumor suppressor protein to G1-arrest cells
- p16 is also known as p16 MTS1 , and p16 CDK4I
- The gene maps to human chromosome 9p21 and has been named MTS1 or CDKN2
- Although the role of the CDK inhibitor p16 as a cell cycle regulator is well established, other aspects of p16 function and the issue of alterations in p16 as a primary event in tumorigenesis are still under investigation.
Compare Similar Items
Show Difference
Antigen: p16
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunoblot
Clone: DCS-50.1/H4
Formulation: In 0.05M sodium phosphate buffer, 0.2% gelatin pH 7.5.
Immunogen: recombinant, human p16
Regulatory Status: RUO
Test Specificity: Recognizes the ∽16kDa p16 protein in Saos-2 cells and bladder tissue. Sold under license of U.S. Patent 6,482,929. Sold under license of U.S. Patent 5,843,756, 6,090,578, and corresponding patents.
Content And Storage: 2°C to 8°C
Isotype: IgG1
Antigen:
p16
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunoblot
Clone:
DCS-50.1/H4
Formulation:
In 0.05M sodium phosphate buffer, 0.2% gelatin pH 7.5.
Immunogen:
recombinant, human p16
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽16kDa p16 protein in Saos-2 cells and bladder tissue. Sold under license of U.S. Patent 6,482,929. Sold under license of U.S. Patent 5,843,756, 6,090,578, and corresponding patents.
Content And Storage:
2°C to 8°C
Isotype:
IgG1
Antigen: p300
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Form: Purified
Applications: Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: NM-11
Formulation: In 0.05M sodium phosphate buffer, 50% glycerol.
Immunogen: recombinant, human p300 protein
Regulatory Status: RUO
Test Specificity: Recognizes the p300 protein in A431, HeLa, and ML-1 cells.
Content And Storage: −20°C
Isotype: IgG1
Antigen:
p300
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Form:
Purified
Applications:
Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
NM-11
Formulation:
In 0.05M sodium phosphate buffer, 50% glycerol.
Immunogen:
recombinant, human p300 protein
Regulatory Status:
RUO
Test Specificity:
Recognizes the p300 protein in A431, HeLa, and ML-1 cells.
Content And Storage:
−20°C
Isotype:
IgG1
Antigen: BrdU
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Multi-species
Form: Purified
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone: Mobu-1
Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen: BrdU-labeled DNA
Regulatory Status: RUO
Test Specificity: Recognizes BrdU (bromodeoxyuridine). Use of this antibody first requires biosynthetic labeling of the target cells with bromodeoxyuridine. This is the preferred BrdU antibody for staining.
Content And Storage: 2°C to 8°C
Isotype: IgG1
Antigen:
BrdU
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Multi-species
Form:
Purified
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Clone:
Mobu-1
Formulation:
In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Immunogen:
BrdU-labeled DNA
Regulatory Status:
RUO
Test Specificity:
Recognizes BrdU (bromodeoxyuridine). Use of this antibody first requires biosynthetic labeling of the target cells with bromodeoxyuridine. This is the preferred BrdU antibody for staining.
Content And Storage:
2°C to 8°C
Isotype:
IgG1
Antigen: 5-Methylcytosine
Classification: Monoclonal
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Multi-species
Form: Purified
Applications: ELISA, Flow Cytometry, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Radioimmune Assays (RIA)
Clone: 162 33 D3
Formulation: In PBS, pH 7.4.
Immunogen: 5-methylcytosine conjugated to ovalbumin
Regulatory Status: RUO
Test Specificity: Recognizes 5-methylcytosine in methylated DNA or RNA in NIH3T3 cells. Affinity purified mouse monoclonal antibody. Detects methylated DNA from a broad range of species.
Content And Storage: −20°C
Isotype: IgG1
Antigen:
5-Methylcytosine
Classification:
Monoclonal
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Multi-species
Form:
Purified
Applications:
ELISA, Flow Cytometry, Immunoblot, Immunoblot, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Radioimmune Assays (RIA)
Clone:
162 33 D3
Formulation:
In PBS, pH 7.4.
Immunogen:
5-methylcytosine conjugated to ovalbumin
Regulatory Status:
RUO
Test Specificity:
Recognizes 5-methylcytosine in methylated DNA or RNA in NIH3T3 cells. Affinity purified mouse monoclonal antibody. Detects methylated DNA from a broad range of species.
Content And Storage:
−20°C
Isotype:
IgG1