NBP21518602

Cytokeratin 19 Antibody (A53-B/A2.26), Novus Biologicals™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP21518602-Each-of-1 In Stock ₹ 52,277.16

NBP21518602 - Each of 1

₹ 52,277.16

In Stock

Quantity

1

Base Price: ₹ 52,277.16

GST (18%): ₹ 9,409.889

Total Price: ₹ 61,687.049

Antigen

Cytokeratin 19

Classification

Monoclonal

Concentration

0.2mg/mL

Dilution

Western Blot 0.5-1ug/ml, Simple Western 10 ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.

P08727

Gene Symbols

KRT19

Immunogen

Human breast cancer MCF-7 cells were used as the immunogen for the Keratin-19 antibody.

Quantity

0.2 mg

Research Discipline

Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers, Neuroscience, Stem Cell Markers

Gene ID (Entrez)

3880

Target Species

Human

Form

Purified

Applications

Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation

Clone

A53-B/A2.26

Conjugate

Unconjugated

Formulation

PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias

CK19, CK-19, cytokeratin 19, Cytokeratin-19,40-kDa keratin intermediate filament, K19cytokeratin-19, K1CS, keratin 19, keratin, type I cytoskeletal 19, keratin, type I, 40-kd, keratin-19, MGC15366

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This MAb reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. Its epitope maps between amino acid 312-335. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

Content And Storage

Store at 4C.

Isotype

IgG2a κ

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Description

  • Cytokeratin 19 Monoclonal specifically detects Cytokeratin 19 in Human samples
  • It is validated for Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Compare Similar Items

Show Difference

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Fischer Scientific

NBP21518602

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Antigen:
Cytokeratin 19

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5-1ug/ml, Simple Western 10 ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.:
P08727

Gene Symbols:
KRT19

Immunogen:
Human breast cancer MCF-7 cells were used as the immunogen for the Keratin-19 antibody.

Quantity:
0.2 mg

Research Discipline:
Cancer, Cell Biology, Cellular Markers, Cytoskeleton Markers, Neuroscience, Stem Cell Markers

Gene ID (Entrez):
3880

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation

Clone:
A53-B/A2.26

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CK19, CK-19, cytokeratin 19, Cytokeratin-19,40-kDa keratin intermediate filament, K19cytokeratin-19, K1CS, keratin 19, keratin, type I cytoskeletal 19, keratin, type I, 40-kd, keratin-19, MGC15366

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This MAb reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. Its epitope maps between amino acid 312-335. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

Content And Storage:
Store at 4C.

Isotype:
IgG2a κ

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NBP21519001

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Antigen:
CD43/Sialophorin

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.:
P16150

Gene Symbols:
SPN

Immunogen:
Myeloblastic KG1 cells were used as the immunogen for this antibody.

Quantity:
0.1 mg

Research Discipline:
B Cell Development and Differentiation Markers, Immunology

Gene ID (Entrez):
6693

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
DF-T1

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CD43 antigen, CD43), Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, sialophorin (gpL115, leukosialin, CD43)

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

Fischer Scientific

NBP21519002

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Antigen:
CD43/Sialophorin

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.:
P16150

Gene Symbols:
SPN

Immunogen:
Myeloblastic KG1 cells were used as the immunogen for this antibody.

Quantity:
0.2 mg

Research Discipline:
B Cell Development and Differentiation Markers, Immunology

Gene ID (Entrez):
6693

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
DF-T1

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
CD43 antigen, CD43), Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, sialophorin (gpL115, leukosialin, CD43)

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

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NBP21519101

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Antigen:
Kappa Light Chain

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5-1ug/ml, Simple Western 10 ug/ml, Flow Cytometry 0.5-2ug/million cells, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, SDS-Page

Gene Accession No.:
P01601

Gene Symbols:
IGKC

Immunogen:
B lymphoma cells

Quantity:
0.1 mg

Research Discipline:
__

Gene ID (Entrez):
3514

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
L1C1

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ