NBP21519101

Kappa Light Chain Antibody (L1C1), Novus Biologicals™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP21519101-Each-of-1 In Stock ₹ 45,004.56

NBP21519101 - Each of 1

₹ 45,004.56

In Stock

Quantity

1

Base Price: ₹ 45,004.56

GST (18%): ₹ 8,100.821

Total Price: ₹ 53,105.381

Antigen

Kappa Light Chain

Classification

Monoclonal

Concentration

0.2mg/mL

Dilution

Western Blot 0.5-1ug/ml, Simple Western 10 ug/ml, Flow Cytometry 0.5-2ug/million cells, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, SDS-Page

Gene Accession No.

P01601

Gene Symbols

IGKC

Immunogen

B lymphoma cells

Purification Method

Protein G purified

Regulatory Status

RUO

Gene ID (Entrez)

3514

Target Species

Human

Form

Purified

Applications

Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

L1C1

Conjugate

Unconjugated

Formulation

PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias

HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809

Host Species

Mouse

Molecular Weight of Antigen

22.5 kDa

Quantity

0.1 mg

Primary or Secondary

Primary

Test Specificity

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage

Store at 4C.

Isotype

IgG1 κ

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Description

  • Description Kappa Light Chain Monoclonal specifically detects Kappa Light Chain in Human samples
  • It is validated for Western Blot, Simple Western, Immunohistochemistry, Immunohistochemistry-Paraffin.

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Fischer Scientific

NBP21519101

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Antigen:
Kappa Light Chain

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5-1ug/ml, Simple Western 10 ug/ml, Flow Cytometry 0.5-2ug/million cells, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, SDS-Page

Gene Accession No.:
P01601

Gene Symbols:
IGKC

Immunogen:
B lymphoma cells

Purification Method:
Protein G purified

Regulatory Status:
RUO

Gene ID (Entrez):
3514

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
L1C1

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809

Host Species:
Mouse

Molecular Weight of Antigen:
22.5 kDa

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

Fischer Scientific

NBP21519102

--


Antigen:
Kappa Light Chain

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5-1ug/ml, Simple Western 10 ug/ml, Flow Cytometry 0.5-2ug/million cells, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, SDS-Page

Gene Accession No.:
P01601

Gene Symbols:
IGKC

Immunogen:
B lymphoma cells

Purification Method:
Protein G purified

Regulatory Status:
RUO

Gene ID (Entrez):
3514

Target Species:
Human

Form:
Purified

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
L1C1

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809

Host Species:
Mouse

Molecular Weight of Antigen:
22.5 kDa

Quantity:
0.2 mg

Primary or Secondary:
Primary

Test Specificity:
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

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NBP21519301

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Antigen:
CD45RA

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Immunogen:
Stimulated human leukocytes were used as immunogen to generate the CD45RA antibody.

Purification Method:
Protein G purified

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Target Species:
Human, Primate

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
158-4D3

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 205kDa-220kDa, identified as CD45RA [Workshop V; Code CD45.38]. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).

Content And Storage:
Store at 4C.

Isotype:
IgG2a κ

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Novus Biologicals

NBP21519601

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Antigen:
Mucin 5AC

Classification:
Monoclonal

Concentration:
0.2mg/mL

Dilution:
Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5ug/ml, Flow (Intracellular)

Gene Accession No.:
P98088

Gene Symbols:
MUC5AC

Immunogen:
M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient

Purification Method:
Protein G purified

Regulatory Status:
RUO

Gene ID (Entrez):
4586

Target Species:
Human, Mouse, Rat, Porcine, Chicken, Feline, Primate, Rabbit, Bovine (Negative)

Form:
Purified

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
45M1

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin

Host Species:
Mouse

Molecular Weight of Antigen:
__

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ