NBP229478

TIMP-3 Antibody, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP229478-Each-of-1 In Stock ₹ 42,737.22

NBP229478 - Each of 1

₹ 42,737.22

In Stock

Quantity

1

Base Price: ₹ 42,737.22

GST (18%): ₹ 7,692.70

Total Price: ₹ 50,429.92

Antigen

TIMP-3

Classification

Polyclonal

Conjugate

Unconjugated

Formulation

PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias

HSMRK222, K222, K222TA2, metalloproteinase inhibitor 3, MIG-5 protein, Protein MIG-5, pseudoinflammatory), SFD, TIMP metallopeptidase inhibitor 3, TIMP-3, tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, Tissue inhibitor of metalloproteinases 3

Host Species

Rabbit

Molecular Weight of Antigen

30 kDa

Quantity

0.1 mg

Research Discipline

Angiogenesis, Apoptosis, Cancer, Hypoxia, Metastasis, Vision

Gene ID (Entrez)

7078

Target Species

Human, Bovine, Canine, Equine, Sheep

Form

Purified

Applications

Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration

0.2 mg/ml

Dilution

Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry 1-2ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/mlimmunohistochemistry 1-2ug/ml, Immunohistochemistry-Paraffin

Gene Accession No.

P35625

Gene Symbols

TIMP3

Immunogen

TIMP-3 (aa175-211) (Uniprot: P35625)

Purification Method

Protein A purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.

Content And Storage

Store at 4C.

Isotype

IgG

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Description

  • TIMP-3 Polyclonal specifically detects TIMP-3 in Human, Mouse, Rat, Bovine, Canine, Equine samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

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Novus Biologicals

NBP229478

--


Antigen:
TIMP-3

Classification:
Polyclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
HSMRK222, K222, K222TA2, metalloproteinase inhibitor 3, MIG-5 protein, Protein MIG-5, pseudoinflammatory), SFD, TIMP metallopeptidase inhibitor 3, TIMP-3, tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, Tissue inhibitor of metalloproteinases 3

Host Species:
Rabbit

Molecular Weight of Antigen:
30 kDa

Quantity:
0.1 mg

Research Discipline:
Angiogenesis, Apoptosis, Cancer, Hypoxia, Metastasis, Vision

Gene ID (Entrez):
7078

Target Species:
Human, Bovine, Canine, Equine, Sheep

Form:
Purified

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
0.2 mg/ml

Dilution:
Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry 1-2ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/mlimmunohistochemistry 1-2ug/ml, Immunohistochemistry-Paraffin

Gene Accession No.:
P35625

Gene Symbols:
TIMP3

Immunogen:
TIMP-3 (aa175-211) (Uniprot: P35625)

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.

Content And Storage:
Store at 4C.

Isotype:
IgG

Img

Novus Biologicals

NBP22947802

--


Antigen:
TIMP-3

Classification:
Polyclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
HSMRK222, K222, K222TA2, metalloproteinase inhibitor 3, MIG-5 protein, Protein MIG-5, pseudoinflammatory), SFD, TIMP metallopeptidase inhibitor 3, TIMP-3, tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, Tissue inhibitor of metalloproteinases 3

Host Species:
Rabbit

Molecular Weight of Antigen:
30 kDa

Quantity:
0.2 mg

Research Discipline:
Angiogenesis, Apoptosis, Cancer, Hypoxia, Metastasis, Vision

Gene ID (Entrez):
7078

Target Species:
Human, Bovine, Canine, Equine, Sheep

Form:
Purified

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
0.2mg/mL

Dilution:
Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry 1-2ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/mlimmunohistochemistry 1-2ug/ml, Immunohistochemistry-Paraffin

Gene Accession No.:
P35625

Gene Symbols:
TIMP3

Immunogen:
A portion of amino acids 175-211 of human TIMP3 was used as immunogen for this antibody.

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.

Content And Storage:
Store at 4C.

Isotype:
IgG

Img

Novus Biologicals

NBP229479

--


Antigen:
Helicobacter Pylori

Classification:
Polyclonal

Conjugate:
Unconjugated

Formulation:
PBS with 0.05% BSA. with 0.05% Sodium Azide

Gene Alias:
H. pylori

Host Species:
Rabbit

Molecular Weight of Antigen:
__

Quantity:
0.1 mg

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human, Mouse, Bovine, Chicken

Form:
Purified

Applications:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
0.2 mg/ml

Dilution:
Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry 1-2ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 1-2ug/ml

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Total Helicobacter pylori lysate was used as immunogen for this antibody.

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
The spiral shaped bacterium Helicobacter pyloriis strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy.H. pyloriis known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcinoma and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. This antibody stains the individual H. pylori bacterium when it presents on the surface of the epithelium or in the cytoplasm of the epithelial cells in biopsy tissue sections from the antrum and body of the stomach.

Content And Storage:
Store at 4C.

Isotype:
IgG

Img

Fischer Scientific

NBP22948005

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Antigen:
CXCL12/SDF-1 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Formulation:
PBS with no preservative

Gene Alias:
CXCL12 chemokine (C-X-C motif) ligand 12, IRH, PBSF, SCYB12, SDF1, SDF1A, SDF1B, TLSF, TPAR1

Host Species:
Rabbit

Molecular Weight of Antigen:
__

Quantity:
0.05 mg

Research Discipline:
__

Gene ID (Entrez):
6387

Target Species:
Human, Rat

Form:
__

Applications:
Western Blot, ELISA, Immunohistochemistry (Paraffin), Functional Assay

Concentration:
LYOPH

Dilution:
Western Blot 0.1-0.2μ/mL, ELISA 0.5-2.0μ/mL, Immunohistochemistry-Paraffin 0.5μ/mL, Functional 2.0-4.0μ/mL

Gene Accession No.:
__

Gene Symbols:
CXCL12

Immunogen:
Antisera to human SDF 1 alpha were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
NBP2-29480 recognises human SDF 1 alpha, otherwise known as CXCL12a, a 68 amino acid stromal cell derived CXC chemokine, which arises from alternative splicing of the SDF 1 gene. The two isoforms, SDF 1 alpha and SDF 1 beta, share an identical amino acid sequence, except for an additional four residues in the C terminal region of the beta isoform.

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Isotype:
IgG