PIPA5118560

Phospho-Ataxin 1 (Ser775) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5118560-Each-of-1 In Stock ₹ 41,539.38

PIPA5118560 - Each of 1

₹ 41,539.38

In Stock

Quantity

1

Base Price: ₹ 41,539.38

GST (18%): ₹ 7,477.088

Total Price: ₹ 49,016.468

Antigen

Phospho-Ataxin 1 (Ser775)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ATXN1

Gene Alias

2900016G23Rik; alternative ataxin1; ataxin 1; Ataxin1; ataxin-1; Atx1; Atx-1; Atx-1-PB; Atxn1; C85907; CG4547; CG4547-PB; D6S504E; dAtx-1; Dmel\CG4547; Dmel_CG4547; ENSMUSG00000074917; Gm10786; OTTHUMP00000016065; SCA1; spinocerebellar ataxia 1; spinocerebellar ataxia 1 homolog; spinocerebellar ataxia type 1 protein; Spinocerebellar ataxia type 1 protein homolog

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20238, 25049, 6310

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P54253, P54254, Q63540

Gene Symbols

ATXN1

Immunogen

A synthesized peptide derived from human ATXN1(Accession P54253), corresponding to amino acid residues around phosphorylated Ser775.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of Ataxin 1 only when phosphorylated at Serine 775
  • The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord
  • Clinically, ADCA has been divided into three groups: ADCA types I-III
  • ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes
  • ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders
  • Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions
  • ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein
  • The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations
  • The function of the ataxins is not known
  • This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1)
  • At least two transcript variants encoding the same protein have been found for this gene.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5118560

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Antigen:
Phospho-Ataxin 1 (Ser775)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATXN1

Gene Alias:
2900016G23Rik; alternative ataxin1; ataxin 1; Ataxin1; ataxin-1; Atx1; Atx-1; Atx-1-PB; Atxn1; C85907; CG4547; CG4547-PB; D6S504E; dAtx-1; Dmel\CG4547; Dmel_CG4547; ENSMUSG00000074917; Gm10786; OTTHUMP00000016065; SCA1; spinocerebellar ataxia 1; spinocerebellar ataxia 1 homolog; spinocerebellar ataxia type 1 protein; Spinocerebellar ataxia type 1 protein homolog

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20238, 25049, 6310

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P54253, P54254, Q63540

Gene Symbols:
ATXN1

Immunogen:
A synthesized peptide derived from human ATXN1(Accession P54253), corresponding to amino acid residues around phosphorylated Ser775.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5118565

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Antigen:
Phospho-RelB (Ser573)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RELB

Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene related B; IREL; I-REL; OTTHUMP00000221313; rel b; RELB; REL-B; RELB proto-oncogene, NF-kB subunit; shep; transcription factor RelB; v-rel avian reticuloendotheliosis viral oncogene homolog B; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3); v-rel reticuloen; v-rel reticuloendotheliosis viral oncogene homolog B; v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19698, 5971

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q01201, Q04863

Gene Symbols:
__

Immunogen:
A synthesized peptide derived from human RelB around the phosphorylation site of Ser573.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA5118572

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Antigen:
Phospho-IRF3 (Ser386)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRF3

Gene Alias:
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
292892, 3661

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q14653

Gene Symbols:
IRF3

Immunogen:
A synthesized peptide derived from human IRF3(Accession Q14653), corresponding to amino acid residues around phosphorylated Ser386.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5118586

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Antigen:
Phospho-FGFR1/FGFR2 (Tyr463, Tyr466)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FGFR2

Gene Alias:
AU043015; AW208770; AW556123; bacteria-expressed kinase; basic fibroblast growth factor receptor 1; BBDS; BEK; BEK fibroblast growth factor receptor; BFGFR; bFGF-R; bFGF-R-1; BFR-1; CD331; CD332; CEK; CEK3; CFD1; c-fgr; Eask; ECCL; ECT1; FGF Receptor 2; FGF receptor-1; FGFBR; fgfr 1; Fgfr1; Fgfr-1; FGFR1/PLAG1 fusion; FGFR2; Fgfr-2; Fgfr7; Fgfr-7; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 2; FLG; FLT2; FLT-2; Fms-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; JWS; KAL2; Keratinocyte growth factor receptor; KGFR; KGFRTr; KSAM; K-SAM; MFR; N-sam; OGD; protein tyrosine kinase, receptor like 14; proto-oncogene c-Fgr; Soluble KGFR; svs; TK14; TK25

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14182, 14183, 2260, 2263, 25022, 79114

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P11362, P16092, P21802, P21803, Q04589

Gene Symbols:
FGFR1, FGFR2

Immunogen:
A synthesized peptide derived from human FGFR1/2 around the phosphorylation site of Tyr463/466.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG