Home Products Antibodies Primary Antibodies PIPA583449
PIPA583449

KLRB1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA583449-Each-of-1 In Stock ₹ 47,015.22

PIPA583449 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

KLRB1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Klrb1

Gene Alias

4930431A04Rik, Antigen 3.2.3, CD161, CD161 antigen-like family member A, CD161 antigen-like family member B, CD161a, CD161b, CLEC5B, C-type lectin domain family 5 member B, EMBL:AAQ11375.1}, Gm4696, HNKR-P1a, Immunoreceptor NKR-P1E, immunoreceptor NKR-P1G, inhibitory receptor NKR-P1B, killer cell lectin like receptor B1, killer cell lectin-like receptor subfamily A member 1 complex, killer cell lectin-like receptor subfamily B member 1, killer cell lectin-like receptor subfamily B member 1 complex, killer cell lectin-like receptor subfamily B member 1A, killer cell lectin-like receptor subfamily B member 1B, killer cell lectin-like receptor subfamily B member 1B allele A, Killer cell lectin-like receptor subfamily B member 1B allele B, killer cell lectin-like receptor subfamily B member 1B allele C, killer cell lectin-like receptor subfamily B member 1D, killer cell lectin-like receptor subfamily B member 1F, killer cell lectin-like receptor subfamily B member 1G, killer cell lectin-like receptor subfamily B, member 1, killer cell lectin-like receptor subfamily B, member 1A, Klrb1, Klrb1a, Klrb1b, klrb1b {ECO:0000312, Klrb1d, Klrb1f, Klrb1g, Klrb6, lectin-like transmembrane protein Nkrp1g, Ly55, Ly-55, Ly55a, ly-55A, Ly55b, ly-55b, Ly55d, ly-55d, lymphocyte antigen 55, lymphocyte antigen 55 complex, locus A, lymphocyte antigen 55 complex, locus B, lymphocyte antigen 55 complex, locus D, lymphocyte antigen 55A, lymphocyte antigen 55b, lymphocyte antigen 55d, MGC138614, natural killer cell receptor, natural killer cell receptor protein NKR-P1A, natural killer cell receptor protein NKR-P1B, natural killer cell receptor-P1, natural killer cell surface protein NKR-P1B allele B6, Natural killer cell surface protein NKR-P1B allele RNK/SD/BN/F344, natural killer cell surface protein NKR-P1B allele SJL/BALB, natural killer cell surface protein NKR-P1B allele TO, natural killer cell surface protein NKR-P1G, Natural killer cell surface protein P1-2, natural killer cell surface protein P1-3.2.3, Natural killer cell surface protein P1A, natural killer lectin-like receptor 1E, natural killer lectin-like receptor protein 1 e, NKR, NKR-P1, NKR-P1 2, NKR-P1 3.2.3, NKR-P1 34, NKR-P1.7, NKRP12, NKRP1A, NKR-P1A, Nkrp1-a, Nkrp1b, Nkr-p1b, Nkrp1-b, Nkrp1d, NKR-P1D, Nkrp1e, Nkr-p1e, Nkrp-1e, Nkrp1g, NKR-P1G, RGD:2975}

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3820

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry

Concentration

0.2 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

Q12918

Gene Symbols

Klrb1

Immunogen

Recombinant protein corresponding to Human KLRB1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA583385

--

Img

Thermo Scientific

PIPA583657

--

Img

Thermo Scientific

PIPA583952

--

Img

Thermo Scientific

PIPA584227

--

Img

Thermo Scientific

PIPA582921

--

Img

Thermo Scientific

PIPA583717

--

Img

Thermo Scientific

PIPA583072

--

Img

Thermo Scientific

PIPA583458

--

Description

  • Immunogen sequence: KCSVDIQQSR NKTTERPGLL NCPIYWQQLR EKCLLFSHTV NPWNNSLADC STKESSLLLI RDKDELIH KLRB1 (Killer cell lectin like receptor subfamily B, member 1, CD-161) protein is classified as a type II membrane protein because it has an external C terminus
  • KLRB1 cell surface antigen is expressed by almost all NK cells and in a small subset of CD3+ve T cells
  • KLRB1 is a homodimeric cell surface protein, comprising two chains with molecular weights ranging from 40-44kDa
  • KLRB1 plays an inhibitory role on natural killer (NK) cells
  • Activation of KLRB1 leads to acid sphingomyelnase/SMPD1 stimulation and an increase in intracellular ceramide
  • Moreover, there is also an activation of AKT1/PKB and RPS6KA1/RSK1 kinase stimulation, and T cell proliferation by anti-CD3
  • KLRB1 acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope and to the N-acetyllactosamine epitope
  • KLRB1 also binds to CLEC2D/LLT1 as a ligand, and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells
  • The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA583449

--

Antigen:
KLRB1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Klrb1
Gene Alias:
4930431A04Rik, Antigen 3.2.3, CD161, CD161 antigen-like family member A, CD161 antigen-like family member B, CD161a, CD161b, CLEC5B, C-type lectin domain family 5 member B, EMBL:AAQ11375.1}, Gm4696, HNKR-P1a, Immunoreceptor NKR-P1E, immunoreceptor NKR-P1G, inhibitory receptor NKR-P1B, killer cell lectin like receptor B1, killer cell lectin-like receptor subfamily A member 1 complex, killer cell lectin-like receptor subfamily B member 1, killer cell lectin-like receptor subfamily B member 1 complex, killer cell lectin-like receptor subfamily B member 1A, killer cell lectin-like receptor subfamily B member 1B, killer cell lectin-like receptor subfamily B member 1B allele A, Killer cell lectin-like receptor subfamily B member 1B allele B, killer cell lectin-like receptor subfamily B member 1B allele C, killer cell lectin-like receptor subfamily B member 1D, killer cell lectin-like receptor subfamily B member 1F, killer cell lectin-like receptor subfamily B member 1G, killer cell lectin-like receptor subfamily B, member 1, killer cell lectin-like receptor subfamily B, member 1A, Klrb1, Klrb1a, Klrb1b, klrb1b {ECO:0000312, Klrb1d, Klrb1f, Klrb1g, Klrb6, lectin-like transmembrane protein Nkrp1g, Ly55, Ly-55, Ly55a, ly-55A, Ly55b, ly-55b, Ly55d, ly-55d, lymphocyte antigen 55, lymphocyte antigen 55 complex, locus A, lymphocyte antigen 55 complex, locus B, lymphocyte antigen 55 complex, locus D, lymphocyte antigen 55A, lymphocyte antigen 55b, lymphocyte antigen 55d, MGC138614, natural killer cell receptor, natural killer cell receptor protein NKR-P1A, natural killer cell receptor protein NKR-P1B, natural killer cell receptor-P1, natural killer cell surface protein NKR-P1B allele B6, Natural killer cell surface protein NKR-P1B allele RNK/SD/BN/F344, natural killer cell surface protein NKR-P1B allele SJL/BALB, natural killer cell surface protein NKR-P1B allele TO, natural killer cell surface protein NKR-P1G, Natural killer cell surface protein P1-2, natural killer cell surface protein P1-3.2.3, Natural killer cell surface protein P1A, natural killer lectin-like receptor 1E, natural killer lectin-like receptor protein 1 e, NKR, NKR-P1, NKR-P1 2, NKR-P1 3.2.3, NKR-P1 34, NKR-P1.7, NKRP12, NKRP1A, NKR-P1A, Nkrp1-a, Nkrp1b, Nkr-p1b, Nkrp1-b, Nkrp1d, NKR-P1D, Nkrp1e, Nkr-p1e, Nkrp-1e, Nkrp1g, NKR-P1G, RGD:2975}
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3820
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q12918
Gene Symbols:
Klrb1
Immunogen:
Recombinant protein corresponding to Human KLRB1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA583450

--

Antigen:
MARK4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mark4
Gene Alias:
2410090P21Rik, C79806, FLJ90097, KIAA1860, MAP/microtubule affinity regulating kinase 4, MAP/microtubule affinity-regulating kinase 4, MAP/microtubule affinity-regulating kinase 4L, MAP/microtubule affinity-regulating kinase like 1, MAP/microtubule affinity-regulating kinase-like 1, Mark4, MARK4 serine/threonine protein kinase, MARK4L, MARK4S, MARKL1, MARKL1L, microtubule affinity regulating kinase 4, Nbla00650, PAR-1D
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
57787
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Concentration:
0.4 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q96L34
Gene Symbols:
Mark4
Immunogen:
Recombinant protein corresponding to Human MARK4
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA583451

--

Antigen:
LATS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LATS2
Gene Alias:
4932411G09Rik, AV277261, AW228608, h-warts, Kinase phosphorylated during mitosis protein, KPM, large tumor suppressor 2, large tumor suppressor homolog 2, large tumor suppressor kinase 2, large tumor suppressor, homolog 2, LATS (large tumor suppressor, Drosophila) homolog 2, LATS, large tumor suppressor, homolog 2, LATS2, serine/threonine kinase KPM, serine/threonine-protein kinase kpm, Serine/threonine-protein kinase LATS2, si:ch211-173o4.2, Warts-like kinase
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26524
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.20 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q9NRM7
Gene Symbols:
LATS2
Immunogen:
Recombinant protein corresponding to Human LATS2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA583453

--

Antigen:
HEF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NEDD9
Gene Alias:
Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4739
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q14511
Gene Symbols:
NEDD9
Immunogen:
Recombinant protein corresponding to Human NEDD9
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG