Tocris Bioscience™ Olaparib

Name: Tocris Bioscience™ Olaparib | Fischer Scientific | Chemikart
Brand: Chemikart
Price: 1 inr
Availability: InStock

Potent PARP inhibitor

Manufacturer: Fischer Scientific

CAS Number: 763113-22-0

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4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2 H)-phthalazinone

Poly(ADP-ribose) Polymerase Inhibitors

0.98

763113-22-0

C24H23FN4O3

Other Options

Product Name	Manufacturer	Price Range
Tocris Bioscience™ Olaparib	--	₹ 9,282.70
Tocris Bioscience™ Olaparib	--	₹ 38,893.00
Biotang Inc Olaparib, > 99%, 250MG, CAS#763113-22-0, M.W.434.46, AZD-2281;KU-59436. RS315-250MG	--	₹ 83,417.92
Medchemexpress LLC HY-10162 1g , Olaparib CAS:763113-22-0 Purity:>98%	--	₹ 28,035.00
Medchemexpress LLC HY-10162 200mg , Olaparib CAS:763113-22-0 Purity:>98%	--	₹ 13,456.80
Apexbio Technology LLC Potent PARP inhibitor 763113-22-0. MFCD13185161	--	₹ 4,717.00
Cayman Chemical Olaparib, 763113-22-0, MFCD13185161, 10mg	--	₹ 6,959.80
Selleck Chemical LLC Olaparib (AZD2281) 10mM/1mL 763113-22-0 Ku-0059436	--	₹ 29,583.60
eMolecules Combi-Blocks 4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one 1g 482934753 QJ-2714 98.000 763113-22-0 MFCD13185161 434.471 C24H23FN4O3	--	₹ 3,333.94
Medchemexpress LLC HY-10162 50mg Medchemexpress, Olaparib CAS:763113-22-0 Purity:>98%	--	₹ 7,849.80

Potent BRAF and CRAF inhibitor...

Olaparib is a potent PARP2 and PARP1 inhibitor (IC50 values are 1 and 5 nM, respectively)
Olaparib abolishes PARP-1 activity at a concentration of 30-100 nM in SW620 cell lysates
BRCA1-deficient cell lines are hypersensitive to PARP inhibition by Olaparib in comparison with BRCA1- and BRCA2-proficient cells
Olaparib potentiates the antitumor activity of the methylating chemotherapeutic agent Temozolomide (Cat
No
2706) in xenograft mouse model
Olaparib is orally bioavailable in rats.