930806

7-Octynoic acid, 8-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-4-yl]

≥95.0%

Manufacturer: Sigma Aldrich

CAS Number: 2429878-72-6

Select a Size

Pack Size SKU Availability Price
50 MG 930806-50-MG In Stock ₹ 17,760.00

930806 - 50 MG

₹ 17,760.00

In Stock

Quantity

1

Base Price: ₹ 17,760.00

GST (18%): ₹ 3,196.80

Total Price: ₹ 20,956.80

Quality Level

100

Assay

≥95.0%

form

powder

functional group

carboxylic acid

storage temp.

2-8°C

SMILES string

O=C(O)CCCCCC#CC1=CC=CC=2C(=O)N(CC12)C3C(=O)NC(=O)CC3

Other Options

Image Product Name Manufacturer Price Range
50-247-4980
eMolecules​ Medchem Express / Lenalidomide-acetylene-C5-COOH / 25mg / 713704569 / HY-129608 / / 2429878-72-6 / [null] / 382.416 / C21H22N2O5
eMolecules​ ₹ 45,789.15
CS-0106899
Lenalidomide-acetylene-C5-COOH
ChemScene ₹ 23,785.68 - ₹ 2,03,205.00
BB75988
2429878-72-6 | LENALIDOMIDE-ACETYLENE-C5-COOH
A2B Chem ₹ 41,667.72 - ₹ 80,169.72

Related Products

Img

Sigma Aldrich

930571

≥95%...

Img

Sigma Aldrich

930555

≥95%...

Img

Sigma Aldrich

930792

≥95.0%...

Img

Sigma Aldrich

930547

≥95.0%...

Img

Sigma Aldrich

920592

--

Img

Sigma Aldrich

920614

--

Img

Sigma Aldrich

920630

--

Img

Sigma Aldrich

920711

--

Description

  • Application: 7-Octynoic acid, 8-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-4-yl] is a functionalized cereblon (CRBN) ligand used in the development of lenalidomide-based protein degrader building blocks. Contains a terminal carboxyl group for conjugation with amine linkers. A basic building block for development of a protein degrader library.Technology Spotlight: Degrader Building Blocks for Targeted Protein DegradationProtein Degrader Building Blocks
  • Other Notes: Targeted Protein Degradation by Small MoleculesDestruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERGSmall-Molecule PROTACS: New Approaches to Protein DegradationTargeted Protein Degradation: from Chemical Biology to Drug Discovery Impact of linker length on the activity of PROTACs

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Compare Similar Items

Show Difference

Img

Sigma Aldrich

930806

≥95.0%...


Quality Level:
100

Assay:
≥95.0%

form:
powder

functional group:
carboxylic acid

storage temp.:
2-8°C

SMILES string:
O=C(O)CCCCCC#CC1=CC=CC=2C(=O)N(CC12)C3C(=O)NC(=O)CC3

Img

Supelco

93081

analytical standard...


Quality Level:
100

Assay:
__

form:
__

functional group:
__

storage temp.:
2-30°C

SMILES string:
OS(O)(=O)=O.Nc1ccc(N)c(Cl)c1

Img

Sigma Aldrich

930814

≥95.0%...


Quality Level:
100

Assay:
≥95.0%

form:
powder

functional group:
carboxylic acid

storage temp.:
2-8°C

SMILES string:
__

Img

Sigma Aldrich

930822

≥95.0%...


Quality Level:
100

Assay:
≥95.0%

form:
powder

functional group:
hydroxyl

storage temp.:
2-8°C

SMILES string:
__