K1684
Thermo Scientific™ GeneBLAzer™ TRα-UAS-blaHEK 293T Assay Kit
Manufacturer: Thermo Scientific™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | K1684-Each-of-1 | In Stock | ₹ 8,98,380.00 |
K1684 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 8,98,380.00
GST (18%): ₹ 1,61,708.40
Total Price: ₹ 10,60,088.40
Alternate Agonists
9-cis-retinoic acid, TTNPB, CD437, AM 580
Assay Entry
Cell-based beta lactamase reporter gene
Content And Storage
TR alpha-UAS-bla HEK 293T cells (K1260)Shipping:Dry IceStorage:-80°C (liquid nitrogen)
Primary Agonist
All-trans-retinoic Acid
Quantity
1 Plate
Target Entry
THRA, TR alpha, NR1A1
Cell Line
HEK 293T
Druggable Target
Nuclear Receptors
Antagonists
AGN 193109
Cell State
Dividing Cells
Detection Method
Fluorescence
Product Line
GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Type
Detection Assay Kit
System Type
GeneBLAzer™
Related Products
Description
- TR alpha-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Thyroid hormone receptor alpha(TR alpha) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line
- GeneBLAzer™UAS-bla HEK 293T cells stably express a beta-lactamase reporter gene under the transcriptional control of an upstream activator sequence (UAS)
- When an agonist binds to the LBD of the GAL4 (DBD)-TR alpha (LBD) fusion protein, the protein binds to the UAS, resulting in expression of beta-lactamase
- TR alpha-UASbla HEK 293T 293 cells are functionally validated for Z' and EC 50 concentrations of T3 Thryoid hormone
- In addition, TR alpha-UAS-bla HEK 293T 293 cells have been tested for assay performance under variable conditions, including DMSO concentration, cell number, stimulation time, and substrate loading time (data available upon request)
- Additional testing data using alternate stimuli are also available.
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Alternate Agonists: 9-cis-retinoic acid, TTNPB, CD437, AM 580
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: TR alpha-UAS-bla HEK 293T cells (K1260)Shipping:Dry IceStorage:-80°C (liquid nitrogen)
Primary Agonist: All-trans-retinoic Acid
Quantity: 1 Plate
Target Entry: THRA, TR alpha, NR1A1
Cell Line: HEK 293T
Druggable Target: Nuclear Receptors
Antagonists: AGN 193109
Cell State: Dividing Cells
Detection Method: Fluorescence
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Type: Detection Assay Kit
System Type: GeneBLAzer™
Alternate Agonists:
9-cis-retinoic acid, TTNPB, CD437, AM 580
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
TR alpha-UAS-bla HEK 293T cells (K1260)Shipping:Dry IceStorage:-80°C (liquid nitrogen)
Primary Agonist:
All-trans-retinoic Acid
Quantity:
1 Plate
Target Entry:
THRA, TR alpha, NR1A1
Cell Line:
HEK 293T
Druggable Target:
Nuclear Receptors
Antagonists:
AGN 193109
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Type:
Detection Assay Kit
System Type:
GeneBLAzer™
Alternate Agonists: __
Assay Entry: __
Content And Storage: __
Primary Agonist: __
Quantity: 1
Target Entry: __
Cell Line: __
Druggable Target: __
Antagonists: __
Cell State: __
Detection Method: __
Product Line: __
Reporter Gene: __
Type: __
System Type: __
Alternate Agonists:
__
Assay Entry:
__
Content And Storage:
__
Primary Agonist:
__
Quantity:
1
Target Entry:
__
Cell Line:
__
Druggable Target:
__
Antagonists:
__
Cell State:
__
Detection Method:
__
Product Line:
__
Reporter Gene:
__
Type:
__
System Type:
__
Alternate Agonists: __
Assay Entry: Cell-based beta lactamase reporter gene
Content And Storage: LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ H1-NFAT-blaHEK293T cells• GeneBLAzer™ H1-NFAT-blaHEK293T Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ H1-NFAT-blaHEK293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Primary Agonist: __
Quantity: 2 x 106Cells
Target Entry: HRH1, H1
Cell Line: 293T (HEK)
Druggable Target: GPCR
Antagonists: __
Cell State: Dividing Cells
Detection Method: Fluorescence
Product Line: GeneBLAzer™
Reporter Gene: BLA (Beta-Lactamase)
Type: Cell Line
System Type: GeneBLAzer™
Alternate Agonists:
__
Assay Entry:
Cell-based beta lactamase reporter gene
Content And Storage:
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.Includes:• GeneBLAzer™ H1-NFAT-blaHEK293T cells• GeneBLAzer™ H1-NFAT-blaHEK293T Assay Protocol• Certificate of AnalysisThe GeneBLAzer™ H1-NFAT-blaHEK293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Primary Agonist:
__
Quantity:
2 x 106Cells
Target Entry:
HRH1, H1
Cell Line:
293T (HEK)
Druggable Target:
GPCR
Antagonists:
__
Cell State:
Dividing Cells
Detection Method:
Fluorescence
Product Line:
GeneBLAzer™
Reporter Gene:
BLA (Beta-Lactamase)
Type:
Cell Line
System Type:
GeneBLAzer™
Alternate Agonists: __
Assay Entry: __
Content And Storage: __
Primary Agonist: __
Quantity: __
Target Entry: __
Cell Line: __
Druggable Target: __
Antagonists: __
Cell State: __
Detection Method: __
Product Line: __
Reporter Gene: __
Type: Bore Buret
System Type: __
Alternate Agonists:
__
Assay Entry:
__
Content And Storage:
__
Primary Agonist:
__
Quantity:
__
Target Entry:
__
Cell Line:
__
Druggable Target:
__
Antagonists:
__
Cell State:
__
Detection Method:
__
Product Line:
__
Reporter Gene:
__
Type:
Bore Buret
System Type:
__