O3514

Bovine Osteopontin

from bovine milk, powder, suitable for cell culture

Manufacturer: Sigma Aldrich

Synonym(S): Bone Sialoprotein-1, Early T Lymphocyte Activation Protein-1 (ETA-1), OPN, Secreted Phosphoprotein 1 (Spp1)

Select a Size

Pack Size SKU Availability Price
50 μG O3514-50-μG In Stock ₹ 74,395.60

O3514 - 50 μG

₹ 74,395.60

In Stock

Quantity

1

Base Price: ₹ 74,395.60

GST (18%): ₹ 13,391.208

Total Price: ₹ 87,786.808

product name

Osteopontin from bovine milk, lyophilized powder

biological source

bovine milk

Quality Level

100

sterility

sterile

form

lyophilized powder

mol wt

~60 kDa

packaging

pkg of 50 μg

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

P31098P31096

shipped in

ambient

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Description

  • General description: Osteopontin (OPN) is a multifunctional protein. It is released by macrophages, T cells and epithelial cells.[1] It has 261 amino acid residues with a molecular mass of 29,283 Da.[2] Osteopontin is also called as uropontin.[3] Osteopontin from bovine milk is highly glycosylated and phosphorylated.[1] SPP1 gene (secreted phosphoprotein 1) codes for osteopontin. This gene is located on human chromosome 4 [3] and cow chromosome 6.[4] It has seven exons and six introns.[3]
  • Biochem/physiol Actions: A secreted, highly acidic, calcium binding, phosphorylated glycoprotein that is chemotactic for macrophages, smooth muscle cells, endothelial cells, and glial cells. In activated macrophages, OPN inhibits nitric oxide production and cytotoxicity. Human, mouse, rat, pig, and bovine OPN share 40% amino acid sequence identity.
  • Physical form: Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 2.5 mg bovine serum albumin.
  • Analysis Note: The biological activity is measured by its ability to mediate 293 cell adhesion.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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lyophilized powder

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