Description

• General description: Phosphatidylserine (PS) is a membrane phospholipid enriched in the cytosolic leaflet of plasma membrane. It comprises 2-10% of total phospholipids.[1] NBD PS is a flurosently labelled phospholipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the headgroup of PS.[2]
• Application: 16:0-06:0 NBD PS has been used as a labelled translocase to detect ATP-dependent translocation across late Golgi membranes.[3] It is also suitable for analysis of phospholipid scramblase 1 (PLSCR1) scrambling in proteoliposomes[4] and to determine enzyme specificity of lipoteichoic acid synthase enzyme (LtaS).[5]
• Biochem/physiol Actions: Phosphatidylserine (PS) is involved in the regulation of many enzymes and structural components.[10] It serves as an essential factor in the clearance of apoptotic cells.[10] It is associated with cognitive disability in Alzheimer′s disease.[11]
• Packaging: 5 mL Amber Glass Screw Cap Vial (810192P-1mg)