F9505

Furazolidone

Manufacturer: Sigma Aldrich

CAS Number: 67-45-8

Synonym(S): 3-(5-Nitrofurfurylideneamino)-2-oxazolidinone

Select a Size

Pack Size SKU Availability Price
10 G F9505-10-G In Stock ₹ 7,826.48

F9505 - 10 G

₹ 7,826.48

In Stock

Quantity

1

Base Price: ₹ 7,826.48

GST (18%): ₹ 1,408.766

Total Price: ₹ 9,235.246

biological source

synthetic

Quality Level

200

form

powder

color

yellow

mp

256-256 °C

solubility

formic acid: 50 mg/mL

antibiotic activity spectrum

Gram-positive bacteriaparasites

Mode of action

enzyme | inhibits

SMILES string

[O-][N+](=O)c1ccc(\C=N\N2CCOC2=O)o1

InChI

1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+

Other Options

Image Product Name Manufacturer Price Range
11-101-5132
VETRANAL™ Furazolidone, MilliporeSigma™ Supelco™
MilliporeSigma Supelco ₹ 7,614.84
PHR2598
Furazolidone
Supelco ₹ 20,394.30
1286800
Furazolidone
Sigma Aldrich ₹ 39,154.03
F9505
Furazolidone
Sigma Aldrich ₹ 7,826.48
CS-4897
Furazolidone
ChemScene ₹ 4,106.88 - ₹ 68,619.12

Related Products

Img

Sigma Aldrich

O0877

quinolone antibiotic...

Img

Sigma Aldrich

N3510

--

Img

Sigma Aldrich

E4632

--

Img

Sigma Aldrich

O8757

fluoroquinolone antibiotic...

Img

Sigma Aldrich

P0106

--

Img

Sigma Aldrich

M5250

powder, ≥98% (TLC)...

Img

Sigma Aldrich

L2906

--

Img

Sigma Aldrich

S0383

--

Description

  • Application: Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA, which leads to the gradual inhibition of monoamine oxidase. It is used to treat anorexia and antagonism of thiamin utilization in poultry[1]. Furazolidone increases thapsigargin-sensitive Ca2+-ATPase in chick cardiac myocytes[2].
  • Biochem/physiol Actions: Furazolidone and its generated free radicals, may bind to DNA and induce cross-links. Bacterial DNA is particularly susceptible to this drug, which results in high levels of mutations (transitions and transversions) in the bacterial chromosome. Its mechanism of action minimizes the development of resistant organisms. Furazolidone is a monoamine oxidase (MAO) inhibitor and is used as a DNA interstrand cross-linking agent.

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Warning

Hazard Statements

H361fd

Precautionary Statements

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 2

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Compare Similar Items

Show Difference

Img

Sigma Aldrich

F9505

--


biological source:
synthetic

Quality Level:
200

form:
powder

color:
yellow

mp:
256-256 °C

solubility:
formic acid: 50 mg/mL

antibiotic activity spectrum:
Gram-positive bacteriaparasites

Mode of action:
enzyme | inhibits

SMILES string:
[O-][N+](=O)c1ccc(\C=N\N2CCOC2=O)o1

InChI:
1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+

Img

Sigma Aldrich

F9507

--


biological source:
__

Quality Level:
200

form:
powder

color:
white to off-white

mp:
__

solubility:
acetic acid: 10 mg/mL

antibiotic activity spectrum:
__

Mode of action:
cell membrane | interferes

SMILES string:
[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])C[C@H](F)C4=CC(=O)C=C[C@]34C

InChI:
1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1

Img

Sigma Aldrich

F9507

--


biological source:
__

Quality Level:
200

form:
powder

color:
white to off-white

mp:
__

solubility:
acetic acid: 10 mg/mL

antibiotic activity spectrum:
__

Mode of action:
cell membrane | interferes

SMILES string:
[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])C[C@H](F)C4=CC(=O)C=C[C@]34C

InChI:
1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1

Img

Sigma Aldrich

F9512

affinity isolated antibody, buffere...


biological source:
goat

Quality Level:
200

form:
buffered aqueous solution

color:
__

mp:
__

solubility:
__

antibiotic activity spectrum:
__

Mode of action:
__

SMILES string:
__

InChI:
__