G1424
Globomycin from Streptomyces hagronensis
Manufacturer: Sigma Aldrich
CAS Number: 67076-74-8
Synonym(S): Globomycin, Glycine, N-(N-(N-(N-(N-(3-hydroxy-2-methyl-1-oxononyl)-N-methylleucyl)-L-alloisoleucyl)-L-seryl)-L-allothreonyl)-, rho-lactone, SF 1902
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | G1424-1-MG | In Stock | ₹ 40,918.50 |
G1424 - 1 MG
In Stock
Quantity
1
Base Price: ₹ 40,918.50
GST (18%): ₹ 7,365.33
Total Price: ₹ 48,283.83
biological source
Streptomyces hagronensis
Quality Level
200
Assay
≥98% (HPLC)
form
powder
color
white
solubility
DMSO: 1 mg/mL
antibiotic activity spectrum
Gram-negative bacteria
Mode of action
enzyme | inhibits
storage temp.
−20°C−20°C
InChI
1S/C32H57N5O9/c1-9-11-12-13-14-24-20(6)32(45)37(8)23(15-18(3)4)29(42)35-26(19(5)10-2)31(44)34-22(17-38)28(41)36-27(21(7)39)30(43)33-16-25(40)46-24/h18-24,26-27,38-39H,9-17H2,1-8H3,(H,33,43)(H,34,44)(H,35,42)(H,36,41)
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences Globomycin from Streptomyces hagronensis | 67076-74-8 | MFCD32661892 | 1MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 64,917.79 |
Related Products
Description
- General description: Globomycin is a cyclic peptide antibiotic, which inhibits the growth of enteric Gram-negative bacteria through cell wall synthesis inhibition.
- Application: Globomycin, a new peptide antibiotic with spheroplast-forming activity. I. Taxonomy of producing organisms and fermentation.: This study explores the taxonomy of the producing organisms of Globomycin and details the fermentation processes involved. This antibiotic shows spheroplast-forming activity, indicating its potential application in targeting bacterial cell wall synthesis (Inukai et al., 1978).
- Biochem/physiol Actions: Globomycin was found to inhibit LspA, a lipoprotein signal peptidase. It eliminates the maturation of pro-lipoproteins by inhibition of the enzyme that converts pro-lipoprotein to lipoprotein, acting as a substrate analog of the signal sequence in the outer membrane of Gram-negative bacteria.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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biological source: Streptomyces hagronensis
Quality Level: 200
Assay: ≥98% (HPLC)
form: powder
color: white
solubility: DMSO: 1 mg/mL
antibiotic activity spectrum: Gram-negative bacteria
Mode of action: enzyme | inhibits
storage temp.: −20°C−20°C
InChI: 1S/C32H57N5O9/c1-9-11-12-13-14-24-20(6)32(45)37(8)23(15-18(3)4)29(42)35-26(19(5)10-2)31(44)34-22(17-38)28(41)36-27(21(7)39)30(43)33-16-25(40)46-24/h18-24,26-27,38-39H,9-17H2,1-8H3,(H,33,43)(H,34,44)(H,35,42)(H,36,41)
biological source:
Streptomyces hagronensis
Quality Level:
200
Assay:
≥98% (HPLC)
form:
powder
color:
white
solubility:
DMSO: 1 mg/mL
antibiotic activity spectrum:
Gram-negative bacteria
Mode of action:
enzyme | inhibits
storage temp.:
−20°C−20°C
InChI:
1S/C32H57N5O9/c1-9-11-12-13-14-24-20(6)32(45)37(8)23(15-18(3)4)29(42)35-26(19(5)10-2)31(44)34-22(17-38)28(41)36-27(21(7)39)30(43)33-16-25(40)46-24/h18-24,26-27,38-39H,9-17H2,1-8H3,(H,33,43)(H,34,44)(H,35,42)(H,36,41)
biological source: __
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biological source: (Mytilus genus)
Quality Level: 200
Assay: ≥85% anhydrous basis (enzymatic)
form: powder
color: white to off-white
solubility: __
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storage temp.: 2-8°C
InChI: 1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-20(45-23-17(36)12(31)10(29)6(2-26)42-23)14(33)18(37)24(43-8)44-19-7(3-27)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23-,24-/m1/s1
biological source:
(Mytilus genus)
Quality Level:
200
Assay:
≥85% anhydrous basis (enzymatic)
form:
powder
color:
white to off-white
solubility:
__
antibiotic activity spectrum:
__
Mode of action:
__
storage temp.:
2-8°C
InChI:
1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-20(45-23-17(36)12(31)10(29)6(2-26)42-23)14(33)18(37)24(43-8)44-19-7(3-27)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23-,24-/m1/s1