T4014
Tobramycin
Aminoglycoside antibiotic
Manufacturer: Sigma Aldrich
CAS Number: 32986-56-4
Synonym(S): 3′-Deoxykanamycin B, Nebramycin Factor 6, O-[3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1→4)]-2-deoxy-D-streptamine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | T4014-100-MG | In Stock | ₹ 15,685.43 |
| 500 MG | T4014-500-MG | In Stock | ₹ 43,733.00 |
T4014 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 15,685.43
GST (18%): ₹ 2,823.377
Total Price: ₹ 18,508.807
biological source
Streptomyces tenebrarius
Quality Level
200
form
powder
storage condition
(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
concentration
≥900 μg/mg (anhydrous)
color
white to off-white
antibiotic activity spectrum
Gram-negative bacteria
Mode of action
protein synthesis | interferes
storage temp.
2-8°C
SMILES string
NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tobramycin Pharmaceutical Secondary Standard, MilliporeSigma™ Supelco™ | MilliporeSigma Supelco | ₹ 13,604.04 | |
 | Tobramycin | Supelco | ₹ 11,994.10 | |
| | Tobramycin | Sigma Aldrich | ₹ 44,230.95 | |
| | Tobramycin | Sigma Aldrich | ₹ 22,526.83 | |
| | Tobramycin | Sigma Aldrich | ₹ 15,685.43 - ₹ 43,733.00 | |
 | 32986-56-4 | Tobramycin | A2B Chem | ₹ 2,481.24 - ₹ 31,828.32 |
Related Products
Description
- General description: Chemical structure: aminoglycoside
- Application: Tobramycin has been used:to study the effect of tobramycin on bacteriophage infected biofilms[3]to study the effects of antibiotics on Pseudomonas aeruginosa strain[4]as a comparator antibiotic[5]
- Biochem/physiol Actions: Tobramycin binds irreversibly to one of two aminoglycoside binding sites on the 30S ribosomal subunit, inhibiting bacterial protein synthesis. Tobramycin may also destabilize bacterial membranes by binding to 16S rRNA (ribosomal RNA). It inhibits translocation and elicits miscoding.[6]Tobramycin is used to treat Pseudomonas aeruginosa lung infections and is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis, and other soft-tissue infections. It is a potential therapy for sinus infections.[7]
- Other Notes: Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Repr. 2
WGK
WGK 3
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biological source: Streptomyces tenebrarius
Quality Level: 200
form: powder
storage condition: (Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
concentration: ≥900 μg/mg (anhydrous)
color: white to off-white
antibiotic activity spectrum: Gram-negative bacteria
Mode of action: protein synthesis | interferes
storage temp.: 2-8°C
SMILES string: NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O
biological source:
Streptomyces tenebrarius
Quality Level:
200
form:
powder
storage condition:
(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
concentration:
≥900 μg/mg (anhydrous)
color:
white to off-white
antibiotic activity spectrum:
Gram-negative bacteria
Mode of action:
protein synthesis | interferes
storage temp.:
2-8°C
SMILES string:
NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O
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SMILES string: CC(O)=O.NC(CO)(CO)CO.OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O
biological source:
__
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200
form:
powder blend
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__
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8.5-10.5 ×
color:
__
antibiotic activity spectrum:
__
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__
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__
SMILES string:
CC(O)=O.NC(CO)(CO)CO.OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O