7180144

Tocris™ ZLD 1039

Potent and selective EZH2 inhibitor

Manufacturer: Fischer Scientific

CAS Number: 1826865-46-6

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Chemical Name or Material

3-[Ethyl(tetrahydro-2H-pyran-4-yl)amino]-N-[(2,3,5,6,7,8-hexahydro-1-methyl-3-oxo-4-isoquinolinyl)methyl]-2-methyl-5-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]benzamide

CAS

1826865-46-6

Molecular Formula

C36H48N6O3

Purity

98%

Other Options

Image Product Name Manufacturer Price Range
58-471-0
Tocris™ ZLD 1039
Fischer Scientific ₹ 24,018.40
58-475-0
Tocris™ ZLD 1039
Fischer Scientific ₹ 1,00,639.09
50-248-7159
eMolecules​ Medchem Express / ZLD1039 / 1mg / 783660389 / HY-116804 / / 1826865-46-6 / [null] / 612.819 / C36H48N6O3
eMolecules​ ₹ 7,556.66

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Description

  • Potent and selective EZH2 inhibitor (IC50 = 5.6 nM) Displays selectivity for EZH2 over a panel of HMTs (inhibition less than 30% at 16 μM) Blocks H3K27 methylation in breast cancer cell lines Induces tumor regression and metastasis in breast cancer xenograft-bearing mice Reactivates silenced tumor suppressors in vivo Orally bioavailable

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Chemical Name or Material:
3-[Ethyl(tetrahydro-2H-pyran-4-yl)amino]-N-[(2,3,5,6,7,8-hexahydro-1-methyl-3-oxo-4-isoquinolinyl)methyl]-2-methyl-5-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]benzamide

CAS:
1826865-46-6

Molecular Formula:
C36H48N6O3

Purity:
98%

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Molecular Formula:
C30H26F2N2O3

Purity:
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