72-401
Tocris Bioscience™ ZNL 02-096
Manufacturer: Tocris Bioscience™
CAS Number: 2414418-49-6
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 72-401-Each-of-1 | In Stock | ₹ 44,619.54 |
72-401 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,619.54
GST (18%): ₹ 8,031.517
Total Price: ₹ 52,651.057
Chemical Name or Material
4-((3-(4-(4-((2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-3-oxo-2,3-dihydro-1 H-pyrazolo[3,4-d]pyrimidin-6-yl)amino)phenyl)piperazin-1-yl)propyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Quantity
1 mg
Molecular Formula
C42H45N11O6
CAS
2414418-49-6
Target
Active Degraders
Purity
0.98
Related Products
Description
- ZNL 02-096 is a potent and selective Wee1 Degrader (PROTAC™) that comprises the Wee1 inhibitor AZD 1775 joined by a linker to the cereblon-binding ligand Pomalidomide (Cat
- No
- 6302)
- ZNL 02-096 selectively degrades Wee1 at submicromolar concentrations, while sparing PLK1, an AZD 1775 secondary target
- In MOLT-4 cells in vitro , ZNL 02-096 induces degradation of Wee1, accumulation of DNA damage, arrest of the cell cycle in the G2/M phase and apoptosis
- The compound shows antiproliferative effects in a panel of 300 cancer cell lines
- PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 4-((3-(4-(4-((2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-3-oxo-2,3-dihydro-1 H-pyrazolo[3,4-d]pyrimidin-6-yl)amino)phenyl)piperazin-1-yl)propyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Quantity: 1 mg
Molecular Formula: C42H45N11O6
CAS: 2414418-49-6
Target: Active Degraders
Purity: 0.98
Chemical Name or Material:
4-((3-(4-(4-((2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-3-oxo-2,3-dihydro-1 H-pyrazolo[3,4-d]pyrimidin-6-yl)amino)phenyl)piperazin-1-yl)propyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Quantity:
1 mg
Molecular Formula:
C42H45N11O6
CAS:
2414418-49-6
Target:
Active Degraders
Purity:
0.98
Chemical Name or Material: (2 S,4 R)-1-(-2-(2-(4-((4 '-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1 '-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxami
Quantity: 5 mg
Molecular Formula: C53H56F3N7O7S2
CAS: 1973403-00-7
Target: Active Degraders
Purity: 0.98
Chemical Name or Material:
(2 S,4 R)-1-(-2-(2-(4-((4 '-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1 '-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxami
Quantity:
5 mg
Molecular Formula:
C53H56F3N7O7S2
CAS:
1973403-00-7
Target:
Active Degraders
Purity:
0.98
Chemical Name or Material: __
Quantity: 1 Kit
Molecular Formula: __
CAS: __
Target: __
Purity: __
Chemical Name or Material:
__
Quantity:
1 Kit
Molecular Formula:
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CAS:
__
Target:
__
Purity:
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Chemical Name or Material: (2 S,4 R)-1-(-2-(2-(2-(2-(4-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6- yl)phenoxy)ethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Quantity: 5 mg
Molecular Formula: C55H57ClFN7O8S
CAS: 2230821-38-0
Target: Active Degraders
Purity: 0.98
Chemical Name or Material:
(2 S,4 R)-1-(-2-(2-(2-(2-(4-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6- yl)phenoxy)ethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Quantity:
5 mg
Molecular Formula:
C55H57ClFN7O8S
CAS:
2230821-38-0
Target:
Active Degraders
Purity:
0.98