74-815-0

Tocris Bioscience™ BCI

Manufacturer: Tocris Bioscience™

CAS Number: 15982-84-0

Select a Size

Pack Size SKU Availability Price
Each of 1 74-815-0-Each-of-1 In Stock ₹ 13,817.94

74-815-0 - Each of 1

₹ 13,817.94

In Stock

Quantity

1

Base Price: ₹ 13,817.94

GST (18%): ₹ 2,487.229

Total Price: ₹ 16,305.169

Chemical Name or Material

3-(Cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1 H-inden-1-one

Quantity

50 mg

Molecular Formula

C22H23NO

CAS

15982-84-0

Target

MKP-1/DUSP1

Purity

0.98

Other Options

Image Product Name Manufacturer Price Range
31-749-610MG
MilliporeSigma™ Calbiochem™ Dual Specificity Protein Phosphatase 1/6 Inhibitor, BCI
MilliporeSigma™ ₹ 14,736.00
NC1882384
Selleck Chemical LLC (E/Z)-BCI 25mg 15982-84-0 BCI, NSC 150117
Selleck Chemical LLC ₹ 89,026.89
AZ92054
15982-84-0 | BCI
A2B Chem ₹ 1,796.76 - ₹ 3,850.20

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Description

  • BCI is an allosteric inhibitor of dual specificity phosphatase DUSP6 and DUSP1 (EC50 values are 8.0 μM and 13.3 μM respectively)
  • Increases P2X7 receptor expression in neuroblastoma cells, reduces cell viability of EGFR or KRAS mutant lung cancer cells, and induces apoptosis in p53-null non-small cell lung cancer cells
  • In an animal model of myocardial infarction, BCI improves heart function, reduces fibrosis, and reduces inflammation by inhibiting macrophage formation
  • Activates FGF signaling in zebrafish embryo development to increase myocardial progenitor population and heart size.

SAFETY INFORMATION

  • Recommended Storage : Store at +4°C

Compare Similar Items

Show Difference

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Tocris Bioscience™

74-815-0

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Chemical Name or Material:
3-(Cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1 H-inden-1-one

Quantity:
50 mg

Molecular Formula:
C22H23NO

CAS:
15982-84-0

Target:
MKP-1/DUSP1

Purity:
0.98

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Fischer Scientific

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Chemical Name or Material:
N-[2-[[(2 S)-2-Methyl-1-pyrrolidinyl]methyl]-1 H-benzimidazol-6-yl]-6-isoquinolinecarboxamide

Quantity:
10 mg

Molecular Formula:
C23H23N5O

CAS:
2561471-13-2

Target:
Bromodomain Inhibitors

Purity:
0.98

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Fischer Scientific

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Chemical Name or Material:
N-[2-[[(2 S)-2-Methyl-1-pyrrolidinyl]methyl]-1 H-benzimidazol-6-yl]-6-isoquinolinecarboxamide

Quantity:
50 mg

Molecular Formula:
C23H23N5O

CAS:
2561471-13-2

Target:
Bromodomain Inhibitors

Purity:
0.98

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Chemical Name or Material:
3-[[4-(Methylamino)-2-quinazolinyl]amino]benzoic acid

Quantity:
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Molecular Formula:
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CAS:
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Target:
Antiviral Compounds

Purity:
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