SML0939
PFI-3
≥98% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 1819363-80-8
Synonym(S): (E)-1-(2-Hydroxyphenyl)-3-((1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | SML0939-5-MG | In Stock | ₹ 13,619.70 |
| 25 MG | SML0939-25-MG | In Stock | ₹ 54,945.00 |
SML0939 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 13,619.70
GST (18%): ₹ 2,451.546
Total Price: ₹ 16,071.246
Quality Level
100
Assay
≥98% (HPLC)
form
powder
color
yellow to orange
solubility
DMSO: 10 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC1=C(C(/C=C/N2[C@H](C3)CN(C4=NC=CC=C4)[C@H]3C2)=O)C=CC=C1
InChI
1S/C19H19N3O2/c23-17-6-2-1-5-16(17)18(24)8-10-21-12-15-11-14(21)13-22(15)19-7-3-4-9-20-19/h1-10,14-15,23H,11-13H2/b10-8+/t14-,15-/m1/s1
InChI key
INAICWLVUAKEPB-QSTFCLMHSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | eMolecules Ambeed / (E)-1-(2-Hydroxyphenyl)-3-((1R4R)-5-(pyridin-2-yl)-25-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one / 1mg / 552733100 / A455988 / / 1819363-80-8 / MFCD28100807 / 321.380 / C19H19N3O2 | eMolecules | ₹ 3,817.69 | |
 | 1819363-80-8 | PFI3 | A2B Chem | ₹ 2,481.24 - ₹ 1,26,543.24 |
Related Products
Description
- Biochem/physiol Actions: SMARCA4 (SWI/SNF related, Matrix associated, Actin dependent Regulator of Chromatin, subfamily A, member 4) is a transcriptional activator and is a component of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. SMARC4 (also known as BRG1) and the related protein SMARCA2 (also known as BRM) contain a bromodomain that is structurally similar to the PolyBromo1 (PB1) 5 bromodomain. PFI-3 is a selective chemical probe for SMARCA bromodomains that inhibits SMARCA2, SMARCA4 and PB1(5) bromodomains. For full characterization details, please visit the PFI-3 probe summary on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
- Features and Benefits: PFI-3 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
Show Difference
Quality Level: 100
Assay: ≥98% (HPLC)
form: powder
color: yellow to orange
solubility: DMSO: 10 mg/mL, clear
storage temp.: 2-8°C
SMILES string: OC1=C(C(/C=C/N2[C@H](C3)CN(C4=NC=CC=C4)[C@H]3C2)=O)C=CC=C1
InChI: 1S/C19H19N3O2/c23-17-6-2-1-5-16(17)18(24)8-10-21-12-15-11-14(21)13-22(15)19-7-3-4-9-20-19/h1-10,14-15,23H,11-13H2/b10-8+/t14-,15-/m1/s1
InChI key: INAICWLVUAKEPB-QSTFCLMHSA-N
Quality Level:
100
Assay:
≥98% (HPLC)
form:
powder
color:
yellow to orange
solubility:
DMSO: 10 mg/mL, clear
storage temp.:
2-8°C
SMILES string:
OC1=C(C(/C=C/N2[C@H](C3)CN(C4=NC=CC=C4)[C@H]3C2)=O)C=CC=C1
InChI:
1S/C19H19N3O2/c23-17-6-2-1-5-16(17)18(24)8-10-21-12-15-11-14(21)13-22(15)19-7-3-4-9-20-19/h1-10,14-15,23H,11-13H2/b10-8+/t14-,15-/m1/s1
InChI key:
INAICWLVUAKEPB-QSTFCLMHSA-N
Quality Level: 100
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 2 mg/mL, clear (warmed)
storage temp.: 2-8°C
SMILES string: CC1=NN=C2N1C3=C(C(C)=C(C)S3)C(C4=CC=C(Cl)C=C4)=NC2CC(OC(C)(C)C)=O
InChI: 1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3
InChI key: DNVXATUJJDPFDM-UHFFFAOYSA-N
Quality Level:
100
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 2 mg/mL, clear (warmed)
storage temp.:
2-8°C
SMILES string:
CC1=NN=C2N1C3=C(C(C)=C(C)S3)C(C4=CC=C(Cl)C=C4)=NC2CC(OC(C)(C)C)=O
InChI:
1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3
InChI key:
DNVXATUJJDPFDM-UHFFFAOYSA-N
Quality Level: 100
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 5 mg/mL, clear (warmed)
storage temp.: 2-8°C
SMILES string: FC(CC1)(F)CCN1C2=NC(NC3CCN(C(C)C)CC3)=C4C(C=C(OCCCN5CCCC5)C(OC)=C4)=N2
InChI: 1S/C29H44F2N6O2/c1-21(2)36-14-7-22(8-15-36)32-27-23-19-25(38-3)26(39-18-6-13-35-11-4-5-12-35)20-24(23)33-28(34-27)37-16-9-29(30,31)10-17-37/h19-22H,4-18H2,1-3H3,(H,32,33,34)
InChI key: RNAMYOYQYRYFQY-UHFFFAOYSA-N
Quality Level:
100
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 5 mg/mL, clear (warmed)
storage temp.:
2-8°C
SMILES string:
FC(CC1)(F)CCN1C2=NC(NC3CCN(C(C)C)CC3)=C4C(C=C(OCCCN5CCCC5)C(OC)=C4)=N2
InChI:
1S/C29H44F2N6O2/c1-21(2)36-14-7-22(8-15-36)32-27-23-19-25(38-3)26(39-18-6-13-35-11-4-5-12-35)20-24(23)33-28(34-27)37-16-9-29(30,31)10-17-37/h19-22H,4-18H2,1-3H3,(H,32,33,34)
InChI key:
RNAMYOYQYRYFQY-UHFFFAOYSA-N
Quality Level: 100
Assay: ≥98% (HPLC)
form: powder
color: white to beige
solubility: DMSO: 20 mg/mL, clear
storage temp.: −20°C
SMILES string: BrC1=CN([C@@H]2O[C@H](CN(CCCNC(NC3=CC=C(C(C)(C)C)C=C3)=O)C(C)C)[C@@H](O)[C@H]2O)C4=C1C(N)=NC=N4
InChI: 1S/C28H40BrN7O4/c1-16(2)35(12-6-11-31-27(39)34-18-9-7-17(8-10-18)28(3,4)5)14-20-22(37)23(38)26(40-20)36-13-19(29)21-24(30)32-15-33-25(21)36/h7-10,13,15-16,20,22-23,26,37-38H,6,11-12,14H2,1-5H3,(H2,30,32,33)(H2,31,34,39)/t20-,22-,23-,26-/m1/s1
InChI key: IQCKJUKAQJINMK-HUBRGWSESA-N
Quality Level:
100
Assay:
≥98% (HPLC)
form:
powder
color:
white to beige
solubility:
DMSO: 20 mg/mL, clear
storage temp.:
−20°C
SMILES string:
BrC1=CN([C@@H]2O[C@H](CN(CCCNC(NC3=CC=C(C(C)(C)C)C=C3)=O)C(C)C)[C@@H](O)[C@H]2O)C4=C1C(N)=NC=N4
InChI:
1S/C28H40BrN7O4/c1-16(2)35(12-6-11-31-27(39)34-18-9-7-17(8-10-18)28(3,4)5)14-20-22(37)23(38)26(40-20)36-13-19(29)21-24(30)32-15-33-25(21)36/h7-10,13,15-16,20,22-23,26,37-38H,6,11-12,14H2,1-5H3,(H2,30,32,33)(H2,31,34,39)/t20-,22-,23-,26-/m1/s1
InChI key:
IQCKJUKAQJINMK-HUBRGWSESA-N