3855716

RACK1 Mouse, Unlabeled, Clone: 20, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

RACK1

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgM

Purification Method

Affinity Purified

Clone

20

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Bovine, Canine, Chicken, Frog, Human, Mouse, Rat

Immunogen

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Several proteins which specifically bind to PKC have been classified as RACKs (receptors for activated C-kinase)
  • RACK1 was cloned from a rat brain cDNA expression library by screening for proteins that bind PKC in the presence of phosphatidylserine, diacylglycerol, and calcium in a PKC overlay assay
  • By sequence homology, RACK1 appears to belong to a superfamily that includes the β subunit of G proteins
  • All of these proteins contain five to eight internal repeat elements known as WD40 motifs, which appear to have a role in protein-protein interactions
  • In addition, RACK1 contains two short sequences homologous to a PKC-binding sequence identified in Annexin I and in the brain PKC inhibitor KCIP
  • The binding of RACK1 to PKC is dose-dependent and occurs at a site on PKC that is distinct from the catalytic domain, indicating that RACK1 is not a PKC substrate
  • Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

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3855716

Mouse Monoclonal Antibody...


Antigen:
RACK1

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgM

Purification Method:
Affinity Purified

Clone:
20

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Bovine, Canine, Chicken, Frog, Human, Mouse, Rat

Immunogen:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2a κ

Purification Method:
Affinity Purified

Clone:
36/E-CADHERIN

Applications:
Western Blot

Conjugate:
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Regulatory Status:
RUO

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Purification Method:
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Clone:
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Applications:
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Conjugate:
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Regulatory Status:
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Target Species:
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Primary or Secondary:
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Concentration:
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Isotype:
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Purification Method:
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Clone:
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Conjugate:
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Regulatory Status:
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