3970598

ERK (pan ERK) Mouse, Unlabeled, Clone: 16, BD

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

ERK (pan ERK)

Concentration

250μg/mL

Classification

Monoclonal

Host Species

Mouse

Research Discipline

Cell Biology

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype

IgG2a

Purification Method

Affinity Purified

Description

Extracellular signal Regulated Kinases

Clone

16

Applications

Western Blot

Conjugate

Unconjugated

Regulatory Status

RUO

Target Species

Canine, Chicken, Frog, Human, Mouse, Rat

Immunogen

Rat ERK2 aa. 219-358

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • The family of serine/threonine kinases known as ERKs (extracellular signal regulated kinases) or MAPKs (mitogen-activated protein kinases) are activated after cell stimulation by a variety of hormones and growth factors
  • Cell stimulation induces a signaling cascade that leads to phosphorylation of MEK (MAPK/ERK kinase) which, in turn, activates ERK via tyrosine and threonine phosphorylation
  • A myriad of proteins represent the downstream effectors for the active ERK and implicate it in the control of cell proliferation and differentiation, as well as regulation of the cytoskeleton
  • Activation of ERK is normally transient and cells possess dual specificity phosphatases that are responsible for its down-regulation
  • Furthermore, multiple studies have shown that elevated ERK activity is associated with some cancers
  • ERK1 may be observable migrating at 44kDa and ERK2 at 42kDa in addition to a 54kDa ERK and a MAP kinase in the 90kDa range
  • Host Species: Mouse Clone: 16 Isotype: IgG2a Species Reactivity: Mouse Immunogen: Rat ERK2 aa
  • 219-358 Formula Weight [Chemical]: 42-85kDa Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

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Fischer Scientific

3970598

Mouse Monoclonal Antibody...


Antigen:
ERK (pan ERK)

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG2a

Purification Method:
Affinity Purified

Description:
Extracellular signal Regulated Kinases

Clone:
16

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat

Immunogen:
Rat ERK2 aa. 219-358

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Mouse Monoclonal Antibody...


Antigen:
FAK

Concentration:
250μg/mL

Classification:
Monoclonal

Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1

Purification Method:
Affinity Purified

Description:
Focal Adhesion Kinase

Clone:
77/FAK

Applications:
Western Blot

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Canine, Chicken, Human, Mouse, Rat

Immunogen:
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Primary or Secondary:
Primary

Content And Storage:
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Antigen:
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Concentration:
250μg/mL

Classification:
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Host Species:
Mouse

Research Discipline:
Cell Biology

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Description:
FN; LETS

Clone:
10

Applications:
Flow Cytometry

Conjugate:
Unconjugated

Regulatory Status:
RUO

Target Species:
Bovine, Canine, Chicken, Human, Mouse, Rat

Immunogen:
Human Fibronectin

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
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Concentration:
0.2mg/mL

Classification:
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Host Species:
Rat

Research Discipline:
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Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG2b

Purification Method:
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Description:
Forkhead box p3; Forkhead box protein p3; JM2; Scurfin; Scurfy; Sf

Clone:
MF23

Applications:
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Conjugate:
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Regulatory Status:
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Target Species:
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Immunogen:
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Primary or Secondary:
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Content And Storage:
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