3970707
Glucocorticoid Receptor Mouse anti-Human, Unlabeled, Clone: 41, BD
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Glucocorticoid Receptor
Concentration
250μg/mL
Classification
Monoclonal
Host Species
Mouse
Research Discipline
Cell Biology
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype
IgG1
Purification Method
Affinity Purified
Clone
41
Applications
Western Blot
Conjugate
Unconjugated
Regulatory Status
RUO
Target Species
Human
Immunogen
Human Glucocorticoid Receptor α aa. 176-289
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
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Description
- Steroid hormone receptors are hormone activated transcriptional regulators that influence genes required for embryonic development and adult homeostasis
- One member of the steroid hormone family is the glucocorticoid receptor
- It contains AF1 and AF2 transactivation domains, a DNA binding domain, and ligand binding domain
- Ligand bound glucocorticoid receptors dimerize at specific palindromic sequences called glucocorticoid response elements (GREs) in the cis-regulatory region of target genes
- Both AF1 and AF2 may be important for initiation or regulation of transcription by interacting with components of the initiation complex or other intermediary factors
- In addition to transactivation, glucocorticoid receptors may also regulate transcription through transrepression of target genes
- Although mechanisms of transrepression are not completely understood; DNA binding alone, DNA binding plus interaction with other transcription factors, or protein-protein interaction without DNA binding are mechanisms that have been implicated
- Thus, glucocorticoid receptors function in the regulation of specific genes that are essential for human development and homeostasis
- Host Species: Mouse Clone: 41 Isotype: IgG1 Species Reactivity: Human Immunogen: Human Glucocorticoid Receptor α aa
- 176-289 Formula Weight [Chemical]: 94kDa Immunofluorescence, Western Blotting
Compare Similar Items
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Antigen: Glucocorticoid Receptor
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 41
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Human
Immunogen: Human Glucocorticoid Receptor α aa. 176-289
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Glucocorticoid Receptor
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
41
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Human
Immunogen:
Human Glucocorticoid Receptor α aa. 176-289
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: gp91[phox]
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 53
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Mouse, Rat
Immunogen: Mouse gp91[phox] aa. 450-556
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
gp91[phox]
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
53
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Mouse, Rat
Immunogen:
Mouse gp91[phox] aa. 450-556
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: GRB2
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 81
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Canine, Chicken, Frog, Human, Mouse, Rat
Immunogen: Rat GRB2 aa. 1-217
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
GRB2
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
81
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Canine, Chicken, Frog, Human, Mouse, Rat
Immunogen:
Rat GRB2 aa. 1-217
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Hic5
Concentration: 250μg/mL
Classification: Monoclonal
Host Species: Mouse
Research Discipline: Cell Biology
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype: IgG1
Purification Method: Affinity Purified
Clone: 34
Applications: Western Blot
Conjugate: Unconjugated
Regulatory Status: RUO
Target Species: Canine, Human, Mouse, Rat
Immunogen: Mouse Hic-5 aa. 73-186
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Hic5
Concentration:
250μg/mL
Classification:
Monoclonal
Host Species:
Mouse
Research Discipline:
Cell Biology
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Isotype:
IgG1
Purification Method:
Affinity Purified
Clone:
34
Applications:
Western Blot
Conjugate:
Unconjugated
Regulatory Status:
RUO
Target Species:
Canine, Human, Mouse, Rat
Immunogen:
Mouse Hic-5 aa. 73-186
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.