5539691

IFN-alpha 2 Antibody (N39), Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

IFN-alpha 2

Concentration

0.2 mg/mL

Applications

Flow Cytometry, SDS-Page, Immunofluorescence

Conjugate

Unconjugated

Host Species

Mouse

Research Discipline

Apoptosis, Cytokine Research

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene ID (Entrez)

3440

Immunogen

Purified recombinant human IFN-alpha2

Primary or Secondary

Primary

Content And Storage

Store at 4C.

Clone

N39

Dilution

Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human

Gene Alias

alpha-2a interferon, IFNA, IFN-alpha-2, IFN-alphaA, INFA2, interferon alpha 2b, interferon alpha A, interferon alpha-2, Interferon alpha-A, interferon, alpha 2, LeIF A, MGC125764, MGC125765

Gene Symbols

IFNA2

Isotype

IgG1 κ

Purification Method

Protein A or G purified

Test Specificity

Recognizes a protein of 16-27kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This MAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this MAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 MAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I an

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Description

  • Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence IFN-alpha 2 Monoclonal specifically detects IFN-alpha 2 in Human samples
  • It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunofluorescence.

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Fischer Scientific

5539691

Mouse Monoclonal Antibody...


Antigen:
IFN-alpha 2

Concentration:
0.2 mg/mL

Applications:
Flow Cytometry, SDS-Page, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Apoptosis, Cytokine Research

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene ID (Entrez):
3440

Immunogen:
Purified recombinant human IFN-alpha2

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Clone:
N39

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Alias:
alpha-2a interferon, IFNA, IFN-alpha-2, IFN-alphaA, INFA2, interferon alpha 2b, interferon alpha A, interferon alpha-2, Interferon alpha-A, interferon, alpha 2, LeIF A, MGC125764, MGC125765

Gene Symbols:
IFNA2

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
Recognizes a protein of 16-27kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This MAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this MAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 MAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I an

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5539697

Mouse Monoclonal Antibody...


Antigen:
IgA

Concentration:
0.2 mg/mL

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Adaptive Immunity, Immunology

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene ID (Entrez):
3493

Immunogen:
Purified human IgA

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Clone:
HISA43

Dilution:
Flow Cytometry 1 - 2 ug/million cells in 0.1ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Alias:
Immunoglobulin A

Gene Symbols:
IGHA1

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
This MAb is specific to heavy chain of IgA and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with both IgA1 and IgA2 subclasses of Alpha heavy chain. It reacts with the third constant domain (CH3) of the alpha chain of IgA molecules. Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through inter-chain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin A (IgA) is the main protein of the mucosal immune system. It is generated by B-cells in gut-associated lymphoid tissues. Daily production of IgA exceeds that of any of the other immunoglobulins. IgA exists mainly in dimers but can also exist as polymers or as monomers. Dimers and polymers contain a joining (J) chain that can be bound by the polymeric immunoglobulin receptor (pIgR) for transportation of the molecule to mucosa

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5539704

Mouse Monoclonal Antibody...


Antigen:
IGF-I

Concentration:
0.2 mg/mL

Applications:
Flow Cytometry, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cell Cycle and Replication

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene ID (Entrez):
3479

Immunogen:
Full-length recombinant human IGF-1 protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Clone:
IGF1/1020

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 1 - 2 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat, Rabbit

Gene Alias:
IBP1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, somatomedin-C

Gene Symbols:
IGF1

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

Img

Fischer Scientific

5539704

Mouse Monoclonal Antibody...


Antigen:
IGF-I

Concentration:
0.2 mg/mL

Applications:
Flow Cytometry, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cell Cycle and Replication

Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene ID (Entrez):
3479

Immunogen:
Full-length recombinant human IGF-1 protein

Primary or Secondary:
Primary

Content And Storage:
Store at 4C.

Clone:
IGF1/1020

Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 1 - 2 ug/ml

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human, Mouse, Rat, Rabbit

Gene Alias:
IBP1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, somatomedin-C

Gene Symbols:
IGF1

Isotype:
IgG1 κ

Purification Method:
Protein A or G purified

Test Specificity:
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.