ABN1640MI

MilliporeSigma™ Prodynorphin/Leumorphin (dynorphin B29) , Rabbit, Unlabeled, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN1640MI-Each-of-1 In Stock ₹ 38,734.72

ABN1640MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

Prodynorphin/Leumorphin (dynorphin B29)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Pdyn

Host Species

Rabbit

Purification Method

Unpurified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This polyclonal antiserum recognizes preproenkephalin-B (a.a. 1-248 of rat sequence), proenkephalin-B (a.a. 22-248 of rat sequence), and leumorphin/dynorphin B-29 (a.a. 221-248 of rat sequence), but not other peptides derived from Proenkephalin-B.

Content And Storage

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications

Western Blot

Concentration

Please refer to lot specific datasheet.

Formulation

Rabbit polyclonal antibody serum with 0.05% Sodium Azide.

Gene Accession No.

P06300

Immunogen

Linear peptide corresponding to rat leumorphin (dynorphin B-29) C-terminal half sequence.

Quantity

50 μL

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_062247

Target Species

Human

Form

Serum

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Description

  • Proenkephalin-B (UniProt P06300; also known as Beta-neoendorphin-dynorphin, Preprodynorphin) is encoded by the Pdyn gene (Gene ID 29190) in rat species
  • Proenkephalin B is an opioid polypeptide hormone involved with chemical signal transduction and cell communication
  • Prodynorphin is a basic building-block of endorphins, the chemical messengers in the brain that appear most heavily involved in the anticipation and experience of pain and the formation of deep emotional bonds critical in learning and memory
  • Prodynorphin is produced with a signal peptide (a.a
  • 1-21) and a propeptide (a.a
  • 22-163) sequence
  • Following the removal of the signal and propeptide sequences, the protein is further processed by proeolytic cleavages to form Alpha-neoendorphin (a.a
  • 166-175), Beta-neoendorphin (a.a
  • 166-174), Big dynorphin (a.a
  • 202-233; Big Dyn), Dynorphin A(1-17) (a.a
  • 202-218; Dyn-A17; Dynorphin A); Dynorphin A(1-13) (a.a
  • 202-214), Dynorphin A(1-8) (a.a
  • 202-209), Leu-enkephalin (a.a
  • 202-206 and 221-225), Leumorphin (Dynorphin B-29; a.a
  • 221-248), and Rimorphin (a.a
  • 221-233; Dynorphin B; Dyn-B; Dynorphin B(1-13)).

Compare Similar Items

Show Difference

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MilliporeSigma™

ABN1640MI

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Antigen:
Prodynorphin/Leumorphin (dynorphin B29)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pdyn

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antiserum recognizes preproenkephalin-B (a.a. 1-248 of rat sequence), proenkephalin-B (a.a. 22-248 of rat sequence), and leumorphin/dynorphin B-29 (a.a. 221-248 of rat sequence), but not other peptides derived from Proenkephalin-B.

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Rabbit polyclonal antibody serum with 0.05% Sodium Azide.

Gene Accession No.:
P06300

Immunogen:
Linear peptide corresponding to rat leumorphin (dynorphin B-29) C-terminal half sequence.

Quantity:
50 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_062247

Target Species:
Human

Form:
Serum

Img

Fischer Scientific

ABN1641-25UL

--


Antigen:
APP585C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antibody detects amyloid precursor protein in human Alzheimer's disese brain. It targets an epitope within 9 amino acids in the vicintiy of APP585 in the C-terminal region.

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
A linear peptide corresponding to 9 amino acids from the C-terminal region of human Amyloid beta A4 protein.

Quantity:
25 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
__

Target Species:
Mouse, Human

Form:
Serum

Img

Fischer Scientific

ABN1641MI

--


Antigen:
APP585C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antibody detects amyloid precursor protein in human Alzheimer's disese brain. It targets an epitope within 9 amino acids in the vicintiy of APP585 in the C-terminal region.

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
A linear peptide corresponding to 9 amino acids from the C-terminal region of human Amyloid beta A4 protein.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_000475

Target Species:
Mouse, Human

Form:
Serum

Img

MilliporeSigma

ABN1642MI

--


Antigen:
APP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This antiserum detects the N-terminal fragment of AEP-cleaved APP at residue 585 (585N), but not the C-terminal fragment (585C) or uncleaved APP. The 585 numbering is based on isoform APP695/PreA4 695 (UniProt P05067-4) sequence. Equivalent site is also present in isoforms APP770 (Asn660; P05067-1), L-APP677 (Asn567; P05067-3), L-APP696 (Asn586; P05067-5), APP714 (Asn604; P05067-6), L-APP733 (Asn623; P05067-7), APP751/PreA4 751 (Asn641; P05067-8), L-APP752 (Asn642; P05067-9), APP639 (Asn529; P05067-10), and isoform 11 (Asn636; P05067-11). Cleavage site is not present in APP305 (P05067-2).

Content And Storage:
Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Western Blot, Immunohistochemistry

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
Synthetic peptide corresponding to the C-terminal end sequence of AEP-cleaved APP 585N fragment.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_958817

Target Species:
Mouse, Human

Form:
Serum