ABS1642
MilliporeSigma™ Rabbit anti-SPTLC1, Polyclonal,
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABS1642-Each-of-1 | In Stock | ₹ 38,734.72 |
ABS1642 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
SPTLC1
Classification
Polyclonal
Gene Accession No.
O15269
Host Species
Rabbit
Purification Method
Unpurified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Serum
Applications
Western Blot
Formulation
Rabbit polyclonal antibody serum with 0.05% sodium azide.
Gene Symbols
SPTLC1; HSAN1; HSAN1A; LCB1
Immunogen
Two linear peptides corresponding to sequences from the N- and a C-terminal regions of human SPTLC1 cytoplasmic domain.
Quantity
100 μL
Research Discipline
Signaling
Gene ID (Entrez)
NP_006406
Content And Storage
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
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Description
- Specifically detects SPTLC1 in Human samples, and it is validated for Western Blotting Serine palmitoyltransferase 1 (EC 2.3.1.50; UniProt O15269; also known as LCB 1, Long chain base biosynthesis protein 1, Serine-palmitoyl-CoA transferase 1, SPT 1, SPT1) is encoded by the SPTLC1 (also known as HSAN1, HSAN1A, LCB1) gene (Gene ID 10558) in human
- Serine palmitoyltransferase (SPT) catalyzes pyridoxal 5-phosphate-/PLP-dependent condensation of L-serine with palmitoyl-CoA to generate 3-ketodihydrosphingosine, the rate-limiting step for the de novo synthesis of sphingolipids
- SPT belongs to the POAS (PLP-dependent α-oxoamine synthase) family of enzymes, members of this family also include 5-amino-levulinic acid synthase, KBL (2-amino-3 ketobutyrate ligase) and AONS (8-amino-7-oxononanoate synthase)
- Unlike the other known POAS family members that all exist as soluble homodimers, SPT is bound to the outer membrane of the endoplasmic reticulum (ER) as a multisubunit complex composed of three distinct subunits, SPTLC1, SPTLC2 and SPTLC3
- SPTLC1 is a 473-amino acid sigle-transmembrane (a.a
- 16-36) protein with a short N-terminal lumenal domain (a.a
- 1-15) and a large C-terminal cytoplasmic domain (a.a
- 37-473)
- Alternative splicing generates an isoform with a truncated cytoplasmic domain (D143 switched to E143, a.a
- 144-473 truncated).
Compare Similar Items
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Antigen: SPTLC1
Classification: Polyclonal
Gene Accession No.: O15269
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Serum
Applications: Western Blot
Formulation: Rabbit polyclonal antibody serum with 0.05% sodium azide.
Gene Symbols: SPTLC1; HSAN1; HSAN1A; LCB1
Immunogen: Two linear peptides corresponding to sequences from the N- and a C-terminal regions of human SPTLC1 cytoplasmic domain.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_006406
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen:
SPTLC1
Classification:
Polyclonal
Gene Accession No.:
O15269
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Serum
Applications:
Western Blot
Formulation:
Rabbit polyclonal antibody serum with 0.05% sodium azide.
Gene Symbols:
SPTLC1; HSAN1; HSAN1A; LCB1
Immunogen:
Two linear peptides corresponding to sequences from the N- and a C-terminal regions of human SPTLC1 cytoplasmic domain.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_006406
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Antigen: DsbA-L
Classification: Polyclonal
Gene Accession No.: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: __
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Formulation: Rabbit polyclonal antiserum with 0.05% sodium azide with 20% glycerol.
Gene Symbols: Gstk1
Immunogen: Myc-tagged full length recombinant protein from mouse.
Quantity: 25 μL
Research Discipline: Signaling
Gene ID (Entrez): __
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Antigen:
DsbA-L
Classification:
Polyclonal
Gene Accession No.:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
__
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Formulation:
Rabbit polyclonal antiserum with 0.05% sodium azide with 20% glycerol.
Gene Symbols:
Gstk1
Immunogen:
Myc-tagged full length recombinant protein from mouse.
Quantity:
25 μL
Research Discipline:
Signaling
Gene ID (Entrez):
__
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Antigen: GSTA4
Classification: Polyclonal
Gene Accession No.: P14942
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Rat
Form: Serum
Applications: Immunohistochemistry (Paraffin), Western Blot
Formulation: Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols: Gsta4
Immunogen: Purified rat liver GST K (YkYk).
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_001100310
Content And Storage: −20°C for one year
Antigen:
GSTA4
Classification:
Polyclonal
Gene Accession No.:
P14942
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Form:
Serum
Applications:
Immunohistochemistry (Paraffin), Western Blot
Formulation:
Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols:
Gsta4
Immunogen:
Purified rat liver GST K (YkYk).
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001100310
Content And Storage:
−20°C for one year
Antigen: GSTT1
Classification: Polyclonal
Gene Accession No.: P30711
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Serum
Applications: Immunohistochemistry (Paraffin), Western Blot
Formulation: Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols: GSTT1
Immunogen: His-tagged recombinant full-length human GSTT1.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_000844
Content And Storage: −20°C for one year
Antigen:
GSTT1
Classification:
Polyclonal
Gene Accession No.:
P30711
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Serum
Applications:
Immunohistochemistry (Paraffin), Western Blot
Formulation:
Rabbit polyclonal antibody in serum with 0.05% sodium azide.
Gene Symbols:
GSTT1
Immunogen:
His-tagged recombinant full-length human GSTT1.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000844
Content And Storage:
−20°C for one year