ABS516AF488

MilliporeSigma™ Adiponectin, Rabbit, Unlabeled, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABS516AF488-Each-of-1 In Stock ₹ 44,491.20

ABS516AF488 - Each of 1

₹ 44,491.20

In Stock

Quantity

1

Base Price: ₹ 44,491.20

GST (18%): ₹ 8,008.416

Total Price: ₹ 52,499.616

Antigen

Adiponectin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Adipoq, Acdc, Acrp30

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This Alexa Fluor™ 488 conjugate was prepared from purified rabbit polyclonal antibody (Mfr. No. ABS516) that was raised against rat adiponectin collagen-like domain and validated for target band detection in both rat and mouse serum samples by Western blotting. Human and Rat adiponectins share 82% sequence identity in the collagen-like domain.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Applications

Immunofluorescence

Concentration

Please refer to lot specific datasheet.

Formulation

Purified rabbit polyclonal antibody conjugate in PBS with 1.5% BSA and 0.05% Sodium Azide.

Gene Accession No.

Q8K3R4

Immunogen

GST-tagged recombinant rat adiponectin collagen-like domain.

Quantity

100 μL

Research Discipline

Signaling

Gene ID (Entrez)

NP_653345

Target Species

Mouse

Form

Purified

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Description

  • Adiponectin (UniProt Q8K3R4; also known as 30kDa adipocyte complement-related protein, ACRP30, Adipocyte complement-related 30kDa protein, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein, apM-1, Gelatin-binding protein) is encoded by the Adipoq (also known as Acdc, Acrp30) gene (Gene ID 246253) in rat
  • Adipokines are adipose tissue-secreted factors involved in vascular function and metabolic disease
  • While most adipokines are proinflammatory and directly responsible for the development of the chronic inflammatory state in obesity, adiponectin is an adipokine with anti-inflammatory and insulin-sensitizing properties
  • Adiponectin mediates it biological activity via adiponection receptor protein 1 and 2 (AdipoR1 and AdipoR2)
  • Both AdipoR1 and AdipoR2 are reported to be ubiquitously expressed with the highest expression in skeletal muscle and liver, respectively
  • Circulating adiponectin levels are reduced in obesity and type II diabetes, whereas weight loss elevates serum adiponectin
  • Likewise, adiponectin overexpression is reported to alleviate metabolic dysfunction independent of weight loss in both genetic and diet-induced animal models of obesity
  • Aadiponectin deficiency is associated with various clinical cardiovascular disorders including myocardial infarction, peripheral artery disease, and endothelial dysfunction
  • Adiponectin is produced with a signal peptide sequence (a.a
  • 1-18 in human and rat sequence; a.a
  • 1-17 in mouse), which is removed postranslationally to yield the mature protein with a collagen-like domain (a.a
  • 42-107 in human and rat, a.a
  • 45-110 in mouse) and a C1q domain (a.a
  • 108-244 in human and rat, a.a
  • 111-247 in mouse).

Compare Similar Items

Show Difference

Img

MilliporeSigma™

ABS516AF488

--


Antigen:
Adiponectin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Adipoq, Acdc, Acrp30

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This Alexa Fluor™ 488 conjugate was prepared from purified rabbit polyclonal antibody (Mfr. No. ABS516) that was raised against rat adiponectin collagen-like domain and validated for target band detection in both rat and mouse serum samples by Western blotting. Human and Rat adiponectins share 82% sequence identity in the collagen-like domain.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Immunofluorescence

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody conjugate in PBS with 1.5% BSA and 0.05% Sodium Azide.

Gene Accession No.:
Q8K3R4

Immunogen:
GST-tagged recombinant rat adiponectin collagen-like domain.

Quantity:
100 μL

Research Discipline:
Signaling

Gene ID (Entrez):
NP_653345

Target Species:
Mouse

Form:
Purified

Img

MilliporeSigma

ABS518MI

--


Antigen:
SLC5A3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2-8°C for 12 months

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
__

Formulation:
Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
__

Immunogen:
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human SLC5A3.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
NP_008864

Target Species:
Human

Form:
__

Img

MilliporeSigma

ABS523MI

--


Antigen:
Lipin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
-20°C in undiluted aliquots for up to 12 months, Avoid Freeze/Thaw Cycles

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide with 50% glycerol.

Gene Accession No.:
__

Immunogen:
linear peptide corresponding to human Lipin-1.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
NP_001248356

Target Species:
Human, Mouse

Form:
__

Img

MilliporeSigma

ABS524MI

--


Antigen:
Lipin-2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
-20°C in undiluted aliquots for up to 12 months, Avoid Freeze/Thaw Cycles

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide with 50% glycerol.

Gene Accession No.:
__

Immunogen:
Linear peptide corresponding to mouse Lipin-2.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
NP_075020

Target Species:
Mouse

Form:
__