ABN1718MI

MilliporeSigma™ SLC4A11, Rabbit, Unlabeled, Polyclonal,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ABN1718MI-Each-of-1 In Stock ₹ 38,734.72

ABN1718MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

SLC4A11

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Slc4a11, BTR1

Host Species

Rabbit

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Specificity of this polyclonal antibody was verified by antigen peptide blocking of target band detection in Western blotting application (Jalimarada, S.S., et al. (2013). Invest. Ophthalmol. Vis. Sci. 54(6):4330-4340). Epitope sequence is conserved between murine and human (UniProt A2AJN7 and Q8NBS3) and present in all four human SLC4A11 spliced isoforms reported by UniProt.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Applications

Western Blot

Concentration

Please refer to lot specific datasheet.

Formulation

Purified rabbit polyclonal antibody in PBS with 0.05% Sodium Azide.

Gene Accession No.

A2AJN7

Immunogen

Linear peptide corresponding to a sequence near the C-terminus of mouse SLC4A11.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_001074631

Target Species

Bovine

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Description

  • Sodium bicarbonate transporter-like protein 11 (UniProt A2AJN7; also known as Bicarbonate transporter-related protein 1, NaBC1, Sodium borate cotransporter 1, Solute carrier family 4 member 11) is encoded by the Slc4a11 (also known as BTR1) gene (Gene ID 269356) in murine species
  • Bicarbonate (HCO3-) transporters are the principal regulators of pH in cells and play a vital role in acid-base movement in various tissues
  • There exist four types of HCO3- transporters, namely Cl-/-HCO3- exchangers, Na+/HCO3- cotransporters (NBCs), a K+/HCO3- cotransporter, and a Na+-driven Cl-/-HCO3- exchanger
  • SLC4A11 is a ubiquitously expressed 14-transmembrane protein existing as dimers within the plasma membrane
  • Originally classified as bicarbonate transporter, later stiudy conducted with cultured primary bovine corneal endothelial cells (BCECs) indicated that SLC4A11 mediates Na+-coupled hydroxide (OH-) transport, but not borate (B(OH)4-) or bicarbonate (HCO3-) transport in corneal endothelium
  • SLC4A11 gene mutations in human are linked to endothelial dystrophies, including CDPD (Corneal dystrophy and perceptive deafness), CHED2 (Corneal dystrophy, endothelial 2, autosomal recessive), and FECD4 (Corneal dystrophy, Fuchs endothelial, 4).

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MilliporeSigma™

ABN1718MI

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Antigen:
SLC4A11

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Slc4a11, BTR1

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Specificity of this polyclonal antibody was verified by antigen peptide blocking of target band detection in Western blotting application (Jalimarada, S.S., et al. (2013). Invest. Ophthalmol. Vis. Sci. 54(6):4330-4340). Epitope sequence is conserved between murine and human (UniProt A2AJN7 and Q8NBS3) and present in all four human SLC4A11 spliced isoforms reported by UniProt.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Applications:
Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody in PBS with 0.05% Sodium Azide.

Gene Accession No.:
A2AJN7

Immunogen:
Linear peptide corresponding to a sequence near the C-terminus of mouse SLC4A11.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_001074631

Target Species:
Bovine

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ABN1720MI

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Antigen:
Ninein

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nin, Kiaa1565

Host Species:
Rabbit

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This polyclonal antiserum targets region between EF-hands 2&5 present in all murine and human ninein spliced isoforms reported by UniProt (Q61043 & Q8N4C6).

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Applications:
Immunofluorescence, Immunohistochemistry, Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Rabbit polyclonal antibody serum with 0.05% Sodium Azide.

Gene Accession No.:
Q61043

Immunogen:
His-tagged recombinant mouse ninein fragment corresponding to the region between EF-hands 2&5.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_001273008

Target Species:
Human

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ABN1721-25UG

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Antigen:
TMEM100

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Host Species:
Rabbit

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
This rabbit polyclonal antibody detects transmembrane protein 100 (TMEM100) in murine cells. It targets an epitope with the 19 amino acids from the N-terminal end.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Accession No.:
__

Immunogen:
KLH-conjugated linear peptide corresponding to 19 amino acids from the N-terminus region of murine Transmembrane protein 100 (TMEM100).

Quantity:
25 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
__

Target Species:
Mouse

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Sigma Aldrich

ABN1721M

from rabbit, purified by affinity c...


Antigen:
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Classification:
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Conjugate:
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Gene:
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Host Species:
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Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Test Specificity:
__

Content And Storage:
__

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
__