ABT1383MI
MilliporeSigma™ phospho-Keratin-18 (Ser51), Rabbit, Unlabeled, Polyclonal,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | ABT1383MI-Each-of-1 | In Stock | ₹ 40,196.94 |
ABT1383MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,196.94
GST (18%): ₹ 7,235.449
Total Price: ₹ 47,432.389
Antigen
phospho-Keratin-18 (Ser51)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KRT18, CYK18, PIG46
Host Species
Rabbit
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This rabbit polyclonal antibody detected upregulated cellular Keratin-18 Ser52 phosphorylation upon phosphatase inhibitors treatment. The Ser52 numbering is based on keratin-18 sequence without the initiation Met1, which was removed posttranslationally.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Applications
Western Blot
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P05783
Immunogen
KLH-conjugated linear peptide corresponding to human Keratin-18 target region sequence containing phosphorylated Ser52.
Quantity
100 μL
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_000215
Target Species
Human
Related Products
Description
- Keratin, type I cytoskeletal 18 (UniProt P05783; also known as Cell proliferation-inducing gene 46 protein, CK-18, Cytokeratin-18, K18, Keratin-18) is encoded by the KRT18 (also known as CYK18, PIG46) gene (Gene ID 3875) in human
- Cytokeratin-18 (Keratin-18 or K18) belongs to a family of highly conserved epithelial-specific intermediate filament (IF) proteins that play an important role in the mechanical stability and integrity of epithelial cells and tissues
- Each epithelium is characterized by its unique keratin expression pattern
- All epithelial cells typically express at least one type-I and one type-II keratin, which form noncovalent heteropolymers
- Keratin 18 is a type I intermediate filament protein that pairs with keratin 8 (K8/K18) in simple epithelia and plays an important role in protecting cells from stress, injury, and apoptosis
- K18 is the only type-I keratin in adult hepatocytes and the major type-I keratin in many colonic tumor cell lines.The structure and function of K8/18 are regulated by posttranslational modifications, such as glycosylation, ubiquitination, and phosphorylation, including K8 phosphorylation on Ser8, Ser23, Ser73, Ser431, and K18 phosphorylation on Ser33 and Ser52
- K18 phosphorylation has been proposed as a progression marker for human chronic hepatitis B (CHB)
- Progressively higher Ser52 phosphorylation is reported in non-cirrhotic and cirrhotic CHB livers, and progressive increase of Ser33 and Ser52 phosphorylation correlates with the elevation of both histological lesions and enzymatic activities of alanine aminotransferase in non-cirrhotic CHB livers.
Compare Similar Items
Show Difference
Antigen: phospho-Keratin-18 (Ser51)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KRT18, CYK18, PIG46
Host Species: Rabbit
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detected upregulated cellular Keratin-18 Ser52 phosphorylation upon phosphatase inhibitors treatment. The Ser52 numbering is based on keratin-18 sequence without the initiation Met1, which was removed posttranslationally.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Applications: Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P05783
Immunogen: KLH-conjugated linear peptide corresponding to human Keratin-18 target region sequence containing phosphorylated Ser52.
Quantity: 100 μL
Research Discipline: Cell Structure
Gene ID (Entrez): NP_000215
Target Species: Human
Antigen:
phospho-Keratin-18 (Ser51)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KRT18, CYK18, PIG46
Host Species:
Rabbit
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detected upregulated cellular Keratin-18 Ser52 phosphorylation upon phosphatase inhibitors treatment. The Ser52 numbering is based on keratin-18 sequence without the initiation Met1, which was removed posttranslationally.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Applications:
Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rabbit polyclonal antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P05783
Immunogen:
KLH-conjugated linear peptide corresponding to human Keratin-18 target region sequence containing phosphorylated Ser52.
Quantity:
100 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_000215
Target Species:
Human
Antigen: __
Classification: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Applications: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Applications:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Antigen: Neurocan, N-terminal
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects Neurocan in fetal and adult rat brain.
Content And Storage: Stable for 1 year at -20°C from date of receipt.
Applications: Immunofluorescence, Immunohistochemistry, Immunoradiometric Assay
Concentration: Please refer to lot specific datasheet.
Formulation: Rabbit polyclonal antiserum with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: GST-tagged recombinant fragement corresponding to 164 amino acids from the N-terminal region of rat Neurocan.
Quantity: 25 μL
Research Discipline: Cell Structure
Gene ID (Entrez): __
Target Species: Mouse, Rat
Antigen:
Neurocan, N-terminal
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects Neurocan in fetal and adult rat brain.
Content And Storage:
Stable for 1 year at -20°C from date of receipt.
Applications:
Immunofluorescence, Immunohistochemistry, Immunoradiometric Assay
Concentration:
Please refer to lot specific datasheet.
Formulation:
Rabbit polyclonal antiserum with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
GST-tagged recombinant fragement corresponding to 164 amino acids from the N-terminal region of rat Neurocan.
Quantity:
25 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
__
Target Species:
Mouse, Rat
Antigen: Glypican-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: __
Host Species: Rabbit
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This rabbit polyclonal antibody detects Glypican-1 in Rat C6 glioma cells.
Content And Storage: Stable for 1 year at -20°C from date of receipt.
Applications: Immunocytochemistry, Western Blot
Concentration: Please refer to lot specific datasheet.
Formulation: Rabbit polyclonal antiserum with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: GST-tagged recombinant fragment corresponding to the first 423 amino acids of rat Glypican-1.
Quantity: 25 μL
Research Discipline: Cell Structure
Gene ID (Entrez): __
Target Species: Rat
Antigen:
Glypican-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rabbit
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This rabbit polyclonal antibody detects Glypican-1 in Rat C6 glioma cells.
Content And Storage:
Stable for 1 year at -20°C from date of receipt.
Applications:
Immunocytochemistry, Western Blot
Concentration:
Please refer to lot specific datasheet.
Formulation:
Rabbit polyclonal antiserum with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
GST-tagged recombinant fragment corresponding to the first 423 amino acids of rat Glypican-1.
Quantity:
25 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
__
Target Species:
Rat