BDB612054
TAF(II)135 Mouse, Unlabeled, Clone: 22, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB612054-Each-of-1 | In Stock | ₹ 24,598.50 |
BDB612054 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,598.50
GST (18%): ₹ 4,427.73
Total Price: ₹ 29,026.23
Antigen
TAF(II)135
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Human TAF[II]135 aa. 454-565
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Human, Mouse
Isotype
IgG1
Applications
Western Blot
Clone
22
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
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Description
- Tightly associated factors (TAFs) play an essential role in transcriptional activation through their interaction with a variety of activators
- TAF[II]135 (a.k.a
- TAF[II]130) is a human homologue of Drosophila TAF[II]110, the first TAF shown to have coactivator activity
- TAF[II]135 contains multiple glutamine-rich regions, as well as a coactivator domain (CAD)
- The glutamine-rich regions of TAF[II]135 facilitate interaction with Sp1 and CREB, which leads to enhancement of both Sp1- and CREB-mediated transcription
- In addition, TAF[II]135 can potentiate transcriptional stimulation by AF-2 of the retinoic acid, thyroid hormone, and vitamine D3 receptors
- However TAF[II]135 does not interact with the AF-2s of the estrogen and retinoid X receptors
- Interestingly, TAF[II]135 enhancement of CREB transcriptional activity may be disrupted by expanded polyglutamine (CAG) repeats found in at least eight different neurodegenerative disorders
- Thus, TAF[II]135 may have important coactivator activities in many different transcription-regulating cell signaling pathways, and interference of TAF[II]135 activity by CAG repeats may be a common mechanism of specific types of neuropathologies
- Host Species: Mouse Clone: 22 Isotype: IgG1 Species Reactivity [for Features Main]: Human Immunogen: Human TAF[II]135 aa
- 454-565 Immunofluorescence, Western Blotting
Compare Similar Items
Show Difference
Antigen: TAF(II)135
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human TAF[II]135 aa. 454-565
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG1
Applications: Western Blot
Clone: 22
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
TAF(II)135
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human TAF[II]135 aa. 454-565
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG1
Applications:
Western Blot
Clone:
22
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: __
Classification: __
Concentration: 1 mg/mL
Formulation: __
Immunogen: __
Quantity: 500 μg
Research Discipline: __
Target Species: __
Isotype: __
Applications: __
Clone: __
Conjugate: __
Host Species: Mouse
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Content And Storage: -20°C
Antigen:
__
Classification:
__
Concentration:
1 mg/mL
Formulation:
__
Immunogen:
__
Quantity:
500 μg
Research Discipline:
__
Target Species:
__
Isotype:
__
Applications:
__
Clone:
__
Conjugate:
__
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Content And Storage:
-20°C
Antigen: BAF47
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Mouse BAF47 aa. 257-359
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat
Isotype: IgG2a
Applications: Western Blot
Clone: 25
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
BAF47
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Mouse BAF47 aa. 257-359
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat
Isotype:
IgG2a
Applications:
Western Blot
Clone:
25
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: BAF47
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Mouse BAF47 aa. 257-359
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat
Isotype: IgG2a
Applications: Western Blot
Clone: 25
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
BAF47
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Mouse BAF47 aa. 257-359
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat
Isotype:
IgG2a
Applications:
Western Blot
Clone:
25
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.