BDB611378
Ataxin-2 Mouse, Unlabeled, Clone: 22, BD
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB611378-Each-of-1 | In Stock | ₹ 24,598.50 |
BDB611378 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,598.50
GST (18%): ₹ 4,427.73
Total Price: ₹ 29,026.23
Antigen
Ataxin-2
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Human Ataxin-2 aa. 713-904
Quantity
50 μg
Research Discipline
Cell Biology
Target Species
Human, Rat
Isotype
IgG1
Applications
Western Blot
Clone
22
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
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Description
- The hereditary ataxias are neurodegenerative disorders characterized by abnormalities of balance due to dysfunction of the cerebellum and cerebellar pathways
- Spinocerebellar ataxias (SCAs) represent a heterogeneous group of disorders with a prevalence of about 1 in 10^5
- Moderate expansion (36 or 37 units) of CAG repeats on the SCA2 gene leads to a gene product, ataxin-2, that has a long polyglutamine tract
- Ataxin-2 is a basic protein with two domains (Sm1 and Sm2) that have been implicated in RNA splicing and protein interaction
- Human ataxin-2 has significant homology with mouse ataxin-2 and ataxin-2 related protein
- Ataxin-2 is expressed as early as day 8 of mouse embryogenesis and is detected in brain, heart, placenta, liver, skeletal muscle, and pancreas, but not in lung or kidney
- Expression increases with age and the protein is localized to the cytoplasm in purkinje cells and other neuronal cell types
- Thus, ataxin-2 is thought to be important for RNA splicing or protein complex formation in many normal tissues, while polyglutamine containing ataxin-2 leads to neuropathology.
Compare Similar Items
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Antigen: Ataxin-2
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human Ataxin-2 aa. 713-904
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 22
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Ataxin-2
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human Ataxin-2 aa. 713-904
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
22
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Mint3
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Mouse Mint3 aa. 63-185
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human, Mouse
Isotype: IgG1
Applications: Western Blot
Clone: 32
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Mint3
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Mouse Mint3 aa. 63-185
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse
Isotype:
IgG1
Applications:
Western Blot
Clone:
32
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: MSH3
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human MSH3 aa. 136-349
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human
Isotype: IgG1
Applications: Western Blot
Clone: 52
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
MSH3
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human MSH3 aa. 136-349
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human
Isotype:
IgG1
Applications:
Western Blot
Clone:
52
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: PI3-Kinase p110α
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human PI3-Kinase p110α aa. 101-300
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Human, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 19
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
PI3-Kinase p110α
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human PI3-Kinase p110α aa. 101-300
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Human, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
19
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.