BDB740411

CD8 Mouse anti-Human, Brilliant Violet 605, Clone: HIT8a, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB740411-Each-of-1 In Stock ₹ 47,614.14

BDB740411 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

CD8

Classification

Monoclonal

Concentration

0.2mg/mL

Description

CD8α; CD8A; CD8 alpha; Leu2a; MAL; T8; p32

Host Species

Mouse

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications

Flow Cytometry

Clone

HIT8a

Conjugate

Brilliant Violet 605

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG1 κ

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Description

  • The HIT8a monoclonal antibody specifically binds to CD8a ( CD8α )
  • CD8α is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily
  • CD8α is expressed by the majority of thymocytes, by subpopulations of αβ T cells and γδ T cells and by some NK cells
  • Cell surface CD8α is expressed either as a disulfide-linked homodimer (CD8αα) or as a heterodimer (CD8αβ) when disulfide-bonded to a CD8 beta chain (CD8β)
  • CD8-positive αβ T cells coexpress both CD8αα homodimers and CD8αβ heterodimers whereas some γδ T cells and NK cells express CD8αα homodimers
  • CD8 plays important roles in T cell activation and selection
  • The extracellular IgSF domain of CD8α binds to a non-polymorphic determinant on HLA class I molecules (α3 domain) and enables CD8 to function as a co receptor with MHC class I-restricted TCR during T cell recognition of antigen
  • The cytoplasmic domain of CD8α associates with Lck, a Src family protein tyrosine kinase that is involved in intracellular signaling
  • Clones HIT8a and RPA-T8 are not cross-blocking.

Compare Similar Items

Show Difference

Img

BD Biosciences

BDB740411

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Antigen:
CD8

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
CD8α; CD8A; CD8 alpha; Leu2a; MAL; T8; p32

Host Species:
Mouse

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
HIT8a

Conjugate:
Brilliant Violet 605

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB740412

--


Antigen:
CD123

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
IL3RA; IL-3RA; IL-3Rα; IL-3R-alpha; Interleukin-3 receptor subunit alpha

Host Species:
Mouse

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
9F5

Conjugate:
Brilliant Violet 605

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB740413

--


Antigen:
CD81

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
TAPA1; Tetraspanin-28; Tspan-28; TSPAN28; CVID6; S5.7; M38

Host Species:
Mouse

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
JS-81

Conjugate:
Brilliant Violet 605

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ

Img

BD Biosciences

BDB740414

--


Antigen:
CD23

Classification:
Monoclonal

Concentration:
0.2mg/mL

Description:
FCER2; FcεRII; Low affinity immunoglobulin epsilon Fc receptor; BLAST-2

Host Species:
Mouse

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Applications:
Flow Cytometry

Clone:
M-L233

Conjugate:
Brilliant Violet 605

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ